As U.S. surpasses 200,000 COVID-19 deaths, Wisconsin sounds alarm over surges in cases

By Maria Caspani and Steve Holland

NEW YORK (Reuters) – Wisconsin Governor Tony Evers on Tuesday declared a new public health emergency and extended a face mask mandate into November to fight a coronavirus flareup in his state, as the number of people who have died across the United States since the pandemic began passed 200,000.

In-person social gatherings have led to cases in Wisconsin skyrocketing among people aged 18 to 24, Evers said, as he pleaded with students who returned to colleges for the fall semester to stay out of bars and wear masks.

“We are seeing an alarming increase in cases across our state, especially on campus,” the governor said in a statement announcing his decision.

The mask mandate, part of a second public health emergency the Democratic governor declared in late July, was due to expire on Monday. A conservative group is contesting the order in court, arguing Evers violated state law by using emergency powers more than once.

Wisconsin has experienced one of the highest percentage increases of coronavirus cases nationwide over the past two weeks, and has the second-highest rate of positive coronavirus tests in the nation at 17%, according to a Reuters tally.

The spike landed Wisconsin back on Chicago’s quarantine travel list, which requires people coming from the state to the city’s north to self-quarantine for 14 days.

“Unfortunately Wisconsin is currently in very poor control when it comes to COVID,” Chicago Department of Public Health Commissioner Allison Arwady said during an afternoon news conference. She said people traveling to and from Wisconsin for work are exempt from the order.

The United States continues to have world’s highest number of COVID-19 deaths. On a weekly average, it is losing about 800 lives each day to the virus, according to a Reuters tally, down from a peak of 2,806 daily deaths recorded on April 15.

In New York City, a global epicenter of the pandemic in the spring, health officials on Tuesday identified a new cluster of COVID-19 cases in the borough of Brooklyn, and noted a marked uptick in infections there and in some other neighborhoods.

‘SOBERING’ AND ‘STUNNING’

During the early months of the pandemic, many experts expected the maximum number of deaths in the United States from the pandemic to be around 200,000.

“The idea of 200,000 deaths is really very sobering and in some respects stunning,” Dr. Anthony Fauci, the top U.S. infectious diseases expert, told CNN.

Thousands of tiny U.S. flags covered part of the National Mall in the nation’s capital on Tuesday to commemorate the lives lost.

The University of Washington’s health institute is forecasting coronavirus fatalities will reach 378,000 by the end of the year, with the daily death toll potentially skyrocketing to 3,000 per day in December.

Six out of every 10,000 residents in the United States has died from COVID-19, one of the highest rates among developed nations.

More than 70% of those who died from the virus in the United States were over the age of 65, according to Centers for Disease Control and Prevention data.

(Reporting by Maria Caspani in New York, Steve Holland, Susan Heavey and Doina Chiacu in Washington and Sangameswaran S in Bengaluru, Editing by Bill Berkrot and Sonya Hepinstall)

U.S. CDC reports 199,462 coronavirus deaths

(Reuters) – The U.S. Centers for Disease Control and Prevention (CDC) on Tuesday reported 6,825,697 cases of the new coronavirus, an increase of 39,345 cases from its previous count, and said that the number of deaths had risen by 438 to 199,462.

The CDC reported its tally of cases of the respiratory illness known as COVID-19, caused by the new coronavirus, as of 4 pm ET on Sept. 21 compared with its previous report a day earlier.

The CDC figures do not necessarily reflect cases reported by individual states.

(Reporting by Vishwadha Chander in Bengaluru; Editing by Vinay Dwivedi)

COVID-19 may damage bone marrow immune cells; another reinfection reported

By Nancy Lapid

(Reuters) – The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

COVID-19 may damage immune cells in the bone marrow

Even bone marrow may not be a safe harbor from the ravages of COVID-19, according to a study that found previously unrecognized changes in newly produced immune cells, called monocytes, released into the blood from bone marrow. To learn more about how the body responds to COVID-19, researchers obtained serial “snapshots” of patients’ immune health by analyzing their immune cells at multiple points during their hospital stays. In COVID-19 patients with more severe disease, the monocytes do not function properly, researchers reported last week in Science Immunology. It was not yet clear whether the monocytes are being released from the bone marrow in an altered state or whether the alterations happen after monocytes enter the blood, coauthor Tracy Hussell of the University of Manchester in the UK told Reuters. Either way, she said, treatments that prevent their release from the bone marrow may help reduce the exaggerated immune response that contributes to poor outcomes in patients with severe COVID-19.

COVID-19 reinfections occur, but remain rare

Another case of reinfection after recovery from COVID-19 has been reported, this time in a healthy young military healthcare provider at a U.S. Department of Defense hospital in Virginia. He was first infected by a patient in March. He recovered within 10 days and “returned … to excellent health,” his doctors reported on Saturday in Clinical Infectious Diseases. Fifty-one days later, he was reinfected by a household member. Genetic studies showed the first and second infections to be from slightly different strains of the virus. The reinfection made him sicker, perhaps because the second strain was more potent, or the household contact infected him with a higher load of virus, doctors said. It was also possible antibodies from the first infection may have triggered his immune system to respond more strongly to the virus the second time his body encountered it. COVID-19 reinfections are still rare, they said. Kristian Anderson, professor of immunology and microbiology at Scripps Research in La Jolla, California, recently told Reuters virus reinfections are always possible. “We don’t know at what frequency reinfections (with the new coronavirus) occur and how that might change over time,” Anderson said. Without further studies, “we can’t conclude what a single case of reinfection means for longevity and robustness of COVID-19 immunity and relevance for a future vaccine,” she added.

Proven immunotherapy approach might be possible in COVID-19

A proven approach to severe virus infections, known as cytotoxic T cell therapy, may be applicable to COVID-19 despite a potential hurdle, researchers said. The approach involves treating critically ill patients with infusions of key immune cells known as T-lymphocytes obtained from people who successfully fought off the same virus. These donor T cells have learned to recognize and target the invading virus. But steroids, which are being increasingly used to treat COVID-19 patients, are toxic to lymphocytes, likely canceling out any beneficial effects of the immunotherapy. In a new report posted on bioRxiv ahead of peer review, researchers describe a possible workaround. They say they have figured out a way to take donor T cells that target the novel coronavirus and make them resistant to the deadly effects of steroids. “We are currently working on … developing clinical trials to determine safety and efficacy,” coauthor Dr. Katy Rezvani of The University of Texas MD Anderson Cancer Center told Reuters.

High COVID-19 mortality seen in assisted-living facilities

Data compiled from more than 4,600 assisted living facilities in seven U.S. states through the end of May showed a four-fold higher COVID-19 fatality rate than in the nearby communities, researchers reported on Monday in the Journal of the American Geriatric Society. In North Carolina and Connecticut, for example, the proportions of COVID-19 cases that were fatal across the state were 3.3% and 9.3%, respectively. In assisted living facilities in those states, the fatality rate climbed to 13% and 31.6%. Unlike nursing homes, assisted living communities are not subject to federal regulation and are not required to collect and report data on COVID-19, coauthor Helena Temkin-Greener of the University of Rochester School of Medicine & Dentistry said in a news release. In this study, and in a separate study of nursing homes her team published on Monday in the same journal, COVID-19 cases were more common in facilities with more minority residents and more residents with dementia, chronic obstructive pulmonary disease, and obesity. “Assisted living communities and their residents urgently need local, state, and the federal governments to pay at least the same level of attention as that given to nursing homes,” Temkin-Greener and colleagues conclude.

(Reporting by Nancy Lapid and Deena Beasley; Editing by Bill Berkrot)

U.S. surpasses grim milestone of 200,000 COVID-19 deaths

By Sangameswaran S

(Reuters) – The death toll from the spread of the coronavirus in the United States exceeded 200,000 on Tuesday, by the far the highest number of any nation.

The United States, on a weekly average, is now losing about 800 lives each day to the virus, according to a Reuters tally. That is down from a peak of 2,806 daily deaths recorded on April 15.

During the early months of the pandemic, 200,000 deaths was regarded by many as the maximum number of lives likely to be lost in the United States to the virus.

The University of Washington’s health institute is forecasting coronavirus fatalities reaching 378,000 by the end of 2020, with the daily death toll skyrocketing to 3,000 per day in December.

Over 70% of those in the United States who have lost their lives to the virus were over the age of 65, according to CDC data.

The southern states of Texas and Florida contributed the most deaths in the United States in the past two weeks and were closely followed by California.

California, Texas and Florida – the three most populous U.S. states – have recorded the most coronavirus infections and have long surpassed the state of New York, which was the epicenter of the outbreak in early 2020. The country as a whole is reporting over 42,000 new infections on average each day and saw cases last week rise on a weekly basis after falling for eight weeks in a row.

Deaths rose 5% last week after falling for four weeks in a row, according to a Reuters analysis.

Six out of every 10,000 residents in the United States has died of the virus, according to Reuters data, one of the highest rates among developed nations.

Brazil follows the United States in the number of overall deaths due to the virus, with over 137,000 fatalities. India has had the world’s highest daily death rate over the last week with total deaths now approaching 100,000.

(Reporting by Sangameswaran S in Bengaluru; Additional reporting by Susan Heavey in Washington; Editing by Lisa Shumaker and Rosalba O’Brien)

New U.S. COVID-19 cases rise 17% in past week, deaths up 5%

(Reuters) – The weekly number of new COVID-19 cases in the United States rose last week for the first time after falling for eight straight weeks, an increase that health experts attributed to schools reopening and parties over the Labor Day holiday.

New cases rose 17% to about 287,000 for the week ended Sept. 20, while deaths rose 5.5% to about 5,400 people after falling for the previous four weeks, according to a Reuters analysis of state and county reports.

Thirteen states have seen weekly infections rise for at least two weeks, up from nine states the previous week, according to the Reuters tally. In Arizona, new cases doubled last week.

On average, more than 776 people a day died from COVID-19 last week, with deaths rising in Arkansas, Kansas and Virginia.

After weeks of declining test rates, an average of 812,000 people a day were tested last week. The country set a record of testing over 1 million people on Saturday.

Nationally, the share of all tests that came back positive for COVID-19 fell for a seventh week to 5.0%, well below a recent peak of nearly 9% in mid-July, according to data from The COVID Tracking Project, a volunteer-run effort to track the outbreak.

However, 26 of the 50 states still have positive test rates above the 5% level that the World Health Organization considers concerning. The highest positive test rates are in the Midwest at over 16% in Idaho, Wisconsin, Iowa and South Dakota.

(Writing by Lisa Shumaker; Graphic by Chris Canipe; Editing by Tiffany Wu)

U.S. CDC reports 199,024 coronavirus deaths

(Reuters) – The U.S. Centers for Disease Control and Prevention (CDC) on Monday reported 6,786,352 cases of the new coronavirus, an increase of 37,417 cases from its previous count, and said that the number of deaths had risen by 270 to 199,024.

The CDC reported its tally of cases of the respiratory illness known as COVID-19, caused by the new coronavirus, as of 4 pm ET on Sept. 20 versus its previous report a day earlier.

The CDC figures do not necessarily reflect cases reported by individual states.

(Reporting by Manojna Maddipatla in Bengaluru; Editing by Aditya Soni)

Factbox: Latest on the worldwide spread of coronavirus

(Reuters) – Coronavirus infections slowed in Australia and New Zealand, while Britain said it was at a “tipping point” on COVID-19 as European countries mulled tightening restrictions to curb a sharp resurgence in cases.

EUROPE

* Britain is at a tipping point on COVID-19, health minister Matt Hancock said, warning that a second national lockdown could be imposed if people don’t follow government rules designed to stop the spread of the virus.

* The Czech government could declare a state of emergency if a recent spike in cases continues in the coming days, Health Minister Adam Vojtech said.

* Protesters in some poorer areas of Madrid that are facing a lockdown to stem a soaring infection rate took to the streets on Sunday to call for better health provisions, complaining of discrimination by the authorities.

* Russia reported 6,148 new cases on Sunday, the second straight day when the daily number of cases exceeded 6,000.

* French health authorities reported 10,569 new confirmed COVID-19 cases on Sunday, down from the previous day’s record increase of 13,498.

ASIA-PACIFIC

* Schools in Seoul and nearby areas resumed in-person classes for the first time in almost a month after daily cases dropped to the lowest levels since mid-August.

* Australia’s coronavirus hotspot of Victoria reported on Monday its lowest daily rise in infections in three months, although state Premier Daniel Andrews said there were no plans yet to ease restrictions sooner than expected.

* New Zealand Prime Minister Jacinda Ardern lifted all coronavirus restrictions across the country, except in second-wave hotspot Auckland, as the number of new infections slowed to a trickle.

AMERICAS

* The United States set a one-day record with over 1 million coronavirus diagnostic tests being performed, but the country needs 6 million to 10 million a day to bring outbreaks under control, according to various experts.

* Brazil and Argentina, Latin American nations seeking more time to commit to the global COVID-19 vaccine facility known as COVAX, said they intend to do so as soon as possible after missing Friday’s deadline.

MIDDLE EAST AND AFRICA

* Morocco signed a deal with Russia’s R-Pharm to buy a COVID-19 vaccine produced under a license from Britain’s AstraZeneca, the health ministry said, as its total number of cases approached 100,000.

* Israel entered a second nationwide lockdown at the onset of the Jewish high-holiday season, forcing residents to stay mostly at home amid a resurgence in new cases.

MEDICAL DEVELOPMENTS

* Moderna Inc said it was on track to produce 20 million doses of its experimental coronavirus vaccine by the end of the year, while maintaining its goal of readying 500 million to 1 billion doses in 2021.

ECONOMIC IMPACT

* British manufacturers see no evidence of a ‘V’-shaped recovery from the pandemic underway and many are planning to slash investment, a business survey showed.

(Compiled by Devika Syamnath and Alex Richardson; Edited by Shounak Dasgupta)

U.S. to surpass grim milestone of 200,000 COVID-19 deaths

By Sangameswaran S

(Reuters) – The death toll from the spread of coronavirus in the United States was approaching over 200,000 lives on Monday, more than double the number of fatalities in India, the country reporting the second-highest number of cases in the world.

The United States, on a weekly average, is now losing about 800 lives each day to the virus, according to a Reuters tally. That is down from a peak of 2,806 daily deaths recorded on April 15.

During the early months of the pandemic, 200,000 deaths was regarded by many as the maximum number of lives likely to be lost in the United States to the virus.

U.S. Centers for Disease Control and Prevention (CDC) Director Robert Redfield recently told Congress that a face mask would provide more guaranteed protection than a vaccine, which would only be broadly available by “late second quarter, third quarter 2021.”

The CDC currently predicts that the U.S. death toll will reach as high as 218,000 by Oct. 10.

The University of Washington’s health institute is forecasting coronavirus fatalities reaching 378,000 by the end of 2020, with the daily death toll skyrocketing to 3,000 per day in December.

Over 70% of those in the United States who have lost their lives to the virus were over the age of 65, according to CDC data.

The southern states of Texas and Florida contributed the most deaths in the United States in the past two weeks and was closely followed by California.

California, Texas and Florida – the three most populous U.S. states – have recorded the most coronavirus infections and have long surpassed the state of New York, which was the epicenter of the outbreak in early 2020. The country as a whole is reporting over 40,000 new infections on average each day.

As it battles a second wave of infections, the United States reported a 17% increase in the number of new cases last week compared with the previous seven days, with deaths rising 7% on average in the last, according to a Reuters analysis.

Six out of every 10,000 residents in the United States has died of the virus, according to Reuters data, one of the highest rates among developed nations.

Brazil follows the United States in the number of overall deaths due to the virus, with over 136,000 fatalities.

(Reporting by Sangameswaran S in Bengaluru; Editing by Lisa Shumaker and Rosalba O’Brien)

Second UK lockdown? PM says second wave inevitable, new restrictions possible

By Guy Faulconbridge, Kate Holton and Andy Bruce

LONDON (Reuters) – British Prime Minister Boris Johnson said he did not want another national lockdown but that new restrictions may be needed because the country was facing an “inevitable” second wave of COVID-19.

Ministers were on Friday reported to be considering a second national lockdown, after new COVID-19 cases almost doubled to 6,000 per day, hospital admissions rose and infection rates soared across parts of northern England and London.

That rise in cases was part of a second wave that was now unstoppable, the prime minister said.

“We are now seeing a second wave coming in…It is absolutely, I’m afraid, inevitable, that we will see it in this country,” Johnson told UK media.

Asked about whether the whole of the country should brace for a new lockdown, rather than just local restrictions, he said: “I don’t want to get into a second national lockdown at all.”

But he did not rule out further national restrictions being brought in.

“When you look at what is happening, you’ve got to wonder whether we need to go further than the rule of six that we brought in on Monday,” he said, referring to the ban on gatherings of more than six people.

The United Kingdom has reported the fifth largest number of deaths from COVID-19 in the world, after the United States, Brazil, India and Mexico, according to data collected by Johns Hopkins University of Medicine.

The UK’s official number of new positive cases shot up by nearly a thousand on Friday to 4,322, the highest since May 8, after a separate ONS model pointed to about 6,000 new cases a day in England in the week to Sept. 10.

That was up from modelling of 3,200 cases per day in the previous week, with the North West and London seen as hotspots.

Health Minister Matt Hancock called a second national lockdown a last resort earlier on Friday and when he was asked about it said: “I can’t give you that answer now.”

SPREADING WIDELY ACROSS ALL AGES

The UK said its reproduction “R” number of infections has risen to a range of 1.1-1.4 from last week’s 1.0-1.2.

“We’re seeing clear signs this virus is now spreading widely across all age groups and I am particularly worried by the increase in rates of admission to hospital and intensive care among older people,” said Yvonne Doyle, Medical Director at Public Health England.

“This could be a warning of far worse things to come.”

Britain imposed new COVID regulations on the North West, Midlands and West Yorkshire from Tuesday. More than 10 million people in the United Kingdom are already in local lockdown, and restrictions for millions more could be on the way.

London Mayor Sadiq Khan said later on Friday that it was “increasingly likely” that additional measures would soon be required in Britain’s biggest city. He said he had seen evidence about the spread of the virus in London which was “extremely” concerning.

COVID-19 cases started to rise again in Britain in September, with between 3,000 and 4,000 positive tests recorded daily in the last week. This is still some way behind France, which is seeing more than 10,000 new cases a day.

“COVID-19 infection rates have increased in most regions, particularly the North West and London,” the ONS said.

The ONS said there had been clear evidence of an increase in the number of people testing positive aged 2 to 11 years, 17 to 24 years and 25 to 34 years.

Johnson was criticized by opposition politicians for his initial response to the outbreak and the government has struggled to ensure sufficient testing in recent weeks.

Asked by LBC radio why the testing system was such a “shambles”, Hancock said Dido Harding, who is in charge of the system, had done an “an extraordinary job.”

(Reporting by Guy Faulconbridge, Kate Holton and Sarah Young; Editing by Raissa Kasolowsky, Mike Collett-White, Philippa Fletcher, William Maclean)

Whole of Iran on coronavirus red alert due to rise in deaths, health official says

(Reuters) – A senior Iranian health official has declared a coronavirus red alert covering the entire country as daily deaths and cases increase at an alarming rate, Iranian state TV reported on Friday.

Iran, one of the Middle Eastern countries hardest hit by the pandemic, has been divided up into white, orange/yellow and red regions based on the number of infections and deaths.

The death toll rose by 144 to 23,952 on Friday, while the total number of identified cases spiked by 3,049 to 416,198, health ministry spokeswoman Sima Sadat Lari said on television.

“The color classification doesn’t make sense anymore. We no longer have orange and yellow. The entire country is red,” deputy health minister Iraj Harirchi said on television.

“If the current course continues, the death toll will reach 45,000,” he added, without giving a time frame.

In the northwestern city of Tabriz, for instance, the number of hospitalized patients had jumped from under 40 a day to 160, and in the Shi’ite Muslim holy city of Qom it had increased from 10 a day to 160, Harirchi said, again without providing a time period for the increases.

He said only a 95% use of masks and a 50% fall in gatherings could reduce the death toll.

(Editing by Hugh Lawson, London Editing Desk)