Fauci bullish on prospects for U.S. vaccine, not worried about China winning race

By Julie Steenhuysen

(Reuters) – The leading U.S. expert on infectious diseases, Dr. Anthony Fauci, predicted on Wednesday the country will meet its goal of a coronavirus vaccine by year’s end and was unmoved by the prospect that China would get there first.

While there are no guarantees, “I feel good about the projected timetable,” Fauci told Reuters in an interview.

His comments follow promising early stage data for the Moderna Inc’s coronavirus vaccine, released on Tuesday, that was developed with scientists at the National Institute of Allergy and Infectious Diseases, which Fauci directs.

Many experts see a safe and effective vaccine as the only way out of the pandemic that has infected millions and killed more than 575,000 people worldwide.

Fauci said Moderna’s results were especially promising because the vaccine appeared to offer the type of protection seen in a natural infection.

In vaccine development, “one of the things that you hope for is that your vaccine induces a response that’s comparable to a natural infection, because theoretically, the best vaccine you could possibly ever get is a natural infection.”

Moderna’s candidate, which is set to enter the last stage of testing on July 27, is just one of more than a hundred vaccines in development globally, but only one of a few contenders that have earned millions of dollars in backing from Operation Warp Speed, the White House program that aims to deliver more than 300 million doses of a safe and effective COVID-19 vaccine by January.

Fauci, who has become a popular and trusted figure during the coronavirus outbreak, came under criticism from President Donald Trump and some of his Republican allies as Fauci cautioned against reopening the U.S. economy too soon.

Asked how he copes with the attacks on his character and allegiance to the president, Fauci told Reuters, “I don’t let it bother me. What we’re doing with vaccines, what we’re doing with therapeutics, what we’re doing with clinical trials is the real substance,” Fauci said.

VACCINE RACE

As U.S. states have begun to reopen businesses and coronavirus infections have soared, some White House officials have pointed fingers at China, where the virus first emerged late last year.

Fauci was unmoved by the prospect that China could cross the finish line first. Although he said he hopes China succeeds, he does not think they will win the vaccine race, at least not by much.

“I think everybody’s sort of on the same track.” If they do get there, he said, “They’re not going to get it particularly sooner than we get it. That’s for sure.”

Ultimately, he hopes multiple successful candidates prevail. “I don’t worry about anybody getting there first.”

Even if a vaccine succeeds in provoking an immune response, Fauci said it is still not clear how long that protection will last.

“These are questions that don’t have answers right now, because we’re only six months into the outbreak.” He said it may take a year before that immunity question is answered.

A recent Reuters poll found that a quarter of Americans are hesitant about taking a vaccine, voicing concern that the record pace of development could compromise safety. Fauci said he is aware of such concerns.

“It’s understandable, but unjustified,” he said. “We’re not compromising safety; we’re not compromising scientific integrity.”

Fauci said the normal development process of waiting for a vaccine to be proven effective before manufacturing begins wastes precious time.

“If the vaccine doesn’t work, the only thing you’ve lost is money.”

(Reporting by Julie Steenhuysen in Chicago; Editing by Lisa Shumaker)

New York’s Cuomo announces new restrictions on bars and restaurants after compliance issues

(Reuters) – Bars and restaurants in New York City that receive three “strikes” for failing to enforce social distancing will be forced to close, Governor Andrew Cuomo said on Thursday.

In addition, bars and restaurants across the state will be allowed to serve alcohol only to patrons also ordering food, and walk-up bar service will not be allowed.

The governor announced the restrictions after numerous reports of compliance issues.

“There is significant evidence of failure to comply,” Cuomo said during a conference call with reporters. “It’s wrong, it’s dangerous, it’s selfish, it’s unacceptable. It’s also illegal.” Separately, an announcement on whether New York City would enter Phase 4 of reopening will be made at 4 p.m. EST on Friday, Cuomo said.

(Reporting by Maria Caspani, Editing by Chizu Nomiyama)

Florida reports biggest one-day increase in COVID-19 deaths since pandemic started

(Reuters) – Florida reported on Thursday the largest one-day increase in deaths from the novel coronavirus since the pandemic began and its second-largest increase in cases ever.

Florida announced 13,965 new cases on Thursday, bringing the total number of cases in the state and the center of the latest outbreak to over 315,775, according to the state health department.

Florida’s COVID deaths rose by 156 to a total of 4,782, surpassing its previous one-day record of 133 new deaths on July 12.

Hospitalizations of patients with COVID-19 was the highest ever reported at 8,626 currently hospitalized, up 321 in the past 24 hours, according to a state agency.

(Writing by Lisa Shumaker, Editing by Franklin Paul)

Target, CVS, Walgreens to require customers wear masks at U.S. stores

(Reuters) – Target Corp, CVS Health Corp and Walgreens Boots Alliance Inc said on Thursday they would require customers wear face coverings while shopping at their U.S. stores, adopting a widely accepted way to curb the spread of the coronavirus.

The move by consumer-facing companies comes as virus cases continue to surge in the United States and deaths exceed 137,000.

On Wednesday, Walmart Inc, Kroger Co and Kohls Corp had decided to implement the policy at all their outlets.

Target said it would launch the policy from August 1, with an exception for those with underlying medical conditions and young children.

Local and state regulations already require shoppers at over 80% of its stores to wear face masks, the retailer said.

Walgreens’ policy will come into effect on Monday, with the company saying it will add store signage and intercom messages to remind shoppers of the new rule.

CVS will also launch the rule at its pharmacies from Monday, but said it was not asking its employees to act as enforcers.

While many companies have recommended masks for months, they were hesitant to make it a requirement over fears of drawing the ire of shoppers, especially after several videos posted online showed confrontations between customers and store staff.

“What we are asking is that customers help protect themselves,” CVS said in a statement.

(Reporting by Uday Sampath in Bengaluru; Editing by Anil D’Silva and Arun Koyyur)

Americans on COVID-19 jobless benefits spent more than when working, study shows

By Jonnelle Marte

(Reuters) – Americans who received enhanced unemployment benefits due to the coronavirus pandemic spent more than when they were working, a study released on Thursday said, adding to concerns about a steep fall in spending when the emergency benefits expire.

The $600 weekly supplement added to jobless benefits as part of the CARES Act helped unemployed households spend 10% more after receiving benefits than they did before the pandemic, according to research by the JP Morgan Chase Institute.

Researchers analyzed transactions for 61,000 households that received unemployment benefits between March and May. Spending dropped for all households as the virus spread and led to business shutdowns, but then rose when households began receiving jobless benefits, the study found.

That contrasts with a typical recession, when households receiving unemployment benefits usually cut spending by 7% because regular jobless benefits amount to only a fraction of a person’s prior earnings, the research found.

The analysis highlighted how the additional unemployment benefits are helping to prop up the U.S. economy and consumer spending after the pandemic led to a surge in joblessness across the country.

More than 30 million Americans are estimated to be receiving unemployment benefits – and they could be pushed off an income cliff when the supplemental benefits, which are due to expire at the end of July, are withdrawn.

“Our estimates suggest that expiration will result in large spending cuts, with potentially negative effects on both households and macroeconomic activity,” the researchers wrote.

The data also reflected the financial pain faced by households that encountered big delays in collecting benefits after states across the country were overwhelmed by applications.

Households that had to wait several weeks for their first unemployment check to arrive cut spending by about 20%, the study found. Spending recovered after the checks arrived.

(Reporting by Jonnelle Marte; editing by Richard Pullin)

Lung radiation shows promise for COVID-19 pneumonia; smoking raises risks

By Nancy Lapid

(Reuters) – The following is a brief roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

Lung radiation may hasten COVID-19 pneumonia recovery

A low dose of radiation to the lungs of COVID-19 pneumonia patients can help them recover more quickly, a small study suggests. Doctors at Emory University in Atlanta treated 10 such patients with lung radiation and compared them to 10 patients of similar ages who received usual care, without radiation. With radiation, the average time to significant improvement was three days, compared to 12 days in the control group.

Other potential effects included a shorter average time to hospital discharge (12 days with radiation versus 20 days without it) and a lower risk of mechanical ventilation (10% with radiation versus 40% without it). But those two differences were too small to rule out the possibility they were due to chance, the researchers found.

The radiation group was “a little older, a little sicker, and their lungs were a little more damaged … but despite that we saw a strong signal of efficacy,” Emory’s Dr. Mohammad Khan told Reuters.

Khan noted that in the radiation group, COVID-19 medications were withheld before and after the treatment, so the results reflect the effect of the radiation alone.

“Radiotherapy,” Khan said, “can reduce the inflammation in the lungs of COVID-19 patients and reduce the cytokines that are causing the inflammation.” Cytokines are proteins made by the immune system. The results on the first five patients have been accepted for publication by the journal Cancer.

The results on all 10 were posted on Tuesday ahead of peer review on the website medRxiv. The researchers have launched a randomized controlled trial of the treatment and expect to eventually include multiple centers.

Smoking may boost severe COVID-19 risk among young adults

Close to one third of young U.S. adults appear to have an elevated risk for severe COVID-19, with smoking their strongest risk factor, according to survey data.

Researchers looked at data from more than 8,000 participants, ages 18 to 25, in the nationally representative National Health Interview Survey for 2016 to 2018. They also looked at participants’ medical conditions identified by the U.S. Centers for Disease Control and Prevention as making people of any age “medically vulnerable” to severe illness from the coronavirus.

Among these are diabetes, heart disease, immune problems, smoking, poorly controlled HIV or AIDS, and respiratory diseases. Overall, 32% of the young adults surveyed were seen as medically vulnerable to severe COVID-19. Among non-smoking young adults, however, only 16% were seen as medically vulnerable.

“Efforts to reduce smoking and e-cigarette use among young adults would likely reduce their medical vulnerability to severe illness,” the researchers said on Monday in the study published in the Journal of Adolescent Health. “Our analysis suggests that risk from smoking and e-cigarette use is highest among young adults who are male, white, and lower income and who are fully or partially uninsured.”

Coronavirus may rarely pass through placenta

It is unclear whether the coronavirus can pass through the womb from mother to fetus.

On Tuesday, doctors in France reported a very rare case that suggests transmission through the placenta may be possible. In the journal Nature Communications, they described a baby born prematurely to a mother with COVID-19. They found the virus in placental tissue as well as in the mother’s and baby’s blood, which suggests that trans-placental transmission of the novel coronavirus virus may be possible, although further studies are needed. Both mother and baby recovered well.

Marian Knight, a professor of maternal and child population health at Oxford University, said the case should not be a major worry for pregnant women. Among the many thousands of babies born to mothers infected with the virus, only around 1% to 2% have been reported to also have had a positive test, Knight said.

Promising results from early trial of new vaccine

Moderna Inc’s experimental vaccine for COVID-19, mRNA-1273, was safe and provoked immune responses in all 45 healthy volunteers in a first-in-humans phase 1 study, researchers reported on Tuesday in the New England Journal of Medicine. Volunteers who got two doses of the vaccine had levels of virus-killing antibodies that exceeded the average levels seen in recovered COVID-19 patients.

Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases, whose researchers developed Moderna’s vaccine candidate, called the results good news. Fauci noted that the study found no serious adverse events and the vaccine produced “reasonably high” levels of virus-killing or neutralizing antibodies.

“If your vaccine can induce a response comparable with natural infection, that’s a winner,” Fauci told Reuters. “That’s why we’re very pleased by the results.” A phase 2 trial testing the vaccine’s efficacy in a larger group started in May.

A much larger phase 3 trial to confirm efficacy and identify rare side effects will begin this month, ultimately including 30,000 participants. Separately, early-stage human trial data on a vaccine being developed by AstraZeneca and Oxford University will be published on July 20, the Lancet medical journal said on Wednesday.

(Reporting by Nancy Lapid, Kate Kelland and Julie Steenhuysen; Editing by Will Dunham)

Rose Parade in California canceled for first time in 76 years due to coronavirus

(Reuters) – The 2021 Tournament of Roses Parade, an annual spectacle held each New Year’s Day since 1891 in Pasadena, California, has been called off due to the coronavirus pandemic, its first cancellation in 76 years, organizers said on Wednesday.

The Rose Parade, an internationally televised procession of flower-bedecked floats, marching bands and equestrian teams, has only been canceled three other times in its history – during the World War Two years of 1942, ’43 and ’45.

“With reluctance and tremendous disappointment, the Pasadena Tournament of Roses Association announces that, in accordance with Governor (Gavin) Newsom’s Phase IV re-opening schedule, and after thoughtful consideration of the restrictions and guidelines in place as a result of COVID-19, we are unable to host the 2021 Rose Parade,” the association said in a statement.

While the 132nd edition of the parade itself was still five months away, preparation for the event typically begins in February.

The Tournament of Roses Association also hosts the Rose Bowl football game each Jan. 1, and planning for this year’s college playoff semifinal is still ongoing, the organization said.

(Reporting by Daniel Trotta and Steve Gorman; editing by Jonathan Oatis and Tom Brown)

Trump rebukes aide Navarro for attacking popular Fauci

By Steve Holland

WASHINGTON (Reuters) – President Donald Trump issued a rare rebuke of his senior adviser Peter Navarro on Tuesday, saying Navarro should not have written a scathing opinion piece about Anthony Fauci, a top government coronavirus expert who is hugely popular.

Navarro, a trade adviser who at times has expanded his reach within the Trump White House, launched an attack on Fauci in an article for USA Today.

“Dr. Anthony Fauci has a good bedside manner with the public, but he has been wrong about everything I have interacted with him on,” Navarro wrote.

The initial lack of a push-back from the White House for the article fed a belief that Navarro’s article was supported at the top levels of the White House.

But departing for a trip to Atlanta, Trump was asked whether Navarro had gone rogue.

“Well he made a statement representing himself. He shouldn’t be doing that. No, I have a very good relationship with Anthony,” Trump said.

A White House official said Trump did not endorse Navarro’s op-ed and that Navarro was told “explicitly in recent days to de-escalate the situation.” The official said that White House chief of staff Mark Meadows is “fully engaged” on the matter and that Meadows thought Navarro’s article was “unacceptable.”

Fauci is a member of the government’s coronavirus task force led by Vice President Mike Pence. The 79-year-old infectious diseases expert aided the search to treat the HIV disease in the 1980’s and is a revered figure for not letting politics intrude on his judgment.

“We’re all on the same team, including Dr. Fauci,” Trump said. “We all want to get rid of this mess.”

Tensions between Trump and Fauci have emerged at times with the president focused on getting Americans back to work and school while Fauci has urged caution to prevent the spread of infection.

Fauci, in an interview with The Atlantic, said the White House’s recent attacks have been a “major mistake on their part.”

“I can’t explain Peter Navarro. He’s in a world by himself,” Fauci said.

He said he had not spoken with Trump “in a while,” but had been working with Pence on the U.S. struggle to gain control of the virus.

(Reporting by Steve Holland; Editing by Howard Goller)

Coronavirus resurgence sidelines Israel’s annexation planning

By Dan Williams

JERUSALEM (Reuters) – A coronavirus resurgence in Israel and divisions within Prime Minister Benjamin Netanyahu’s government have sidelined its plans to annex parts of the occupied West Bank, officials said.

Although the conservative Netanyahu and Defense Minister Benny Gantz, his centrist coalition partner, agreed the government could begin moving on annexation as of July 1, there has been “close to zero” cabinet-level discussion on the issue, one senior minister told Reuters.

And with no agreement with Washington yet on the modalities of the move under a peace proposal announced by President Donald Trump, any step soon to extend Israeli sovereignty to Jewish settlements and the Jordan Valley in the West Bank seems unlikely.

The Palestinians have rejected the Trump plan. European and Arab powers have warned of diplomatic blow-back if Israel unilaterally annexes land Palestinians seek for a state.

Netanyahu, meanwhile, is preoccupied with new coronavirus transmissions that aides said could necessitate renewed lockdowns. Unemployment has hit a record 21% and anti-government protests have turned increasingly violent.

A poll by the non-partisan Israel Democracy Institute on Tuesday found only 29.5% of the public trust Netanyahu’s handling of the crisis.

There has been open opposition from Gantz’s Blue and White party, which makes it hard to persuade Washington that any annexations would enjoy sweeping Israeli support.

“It’s a matter of right plan, wrong time,” a senior Blue and White minister said. “We are in the middle of the biggest crisis Israel has seen in decades…and it would be irresponsible and insensitive to tend to anything else at the moment.”

Gantz has predicted the crisis could last until late 2021.

Another official, who requested anonymity, said more than a week had passed since Israeli delegates last spoke to U.S. envoys on annexation under the Trump blueprint, which envisages Israeli sovereignty over up to 30% of West Bank land.

Asked for comment, Netanyahu’s office said it had “no updates at this time”.

Several ministers from Netanyahu’s Likud party want the move implemented now. Some privately voice concern that Trump’s attention will drift as the November presidential election approaches, and that presumptive Democratic candidate Joe Biden has come out against annexation.

(Editing by Jeffrey Heller and Mark Heinrich)

Quarantine or not, tourists still flock to New Mexico

By Andrew Hay

RED RIVER, N.M. (Reuters) – In the New Mexico mountain resort of Red River, tourists from Texas stroll along Main Street, most disregarding Governor Michelle Lujan Grisham’s orders they quarantine and wear masks.

It’s the same in other New Mexican tourist towns such as Taos and Santa Fe, except nearly all their visitors wear face coverings – surrounded by signs warning of fines if they don’t.

Like governors in at least 15 states, Democrat Lujan Grisham has ordered out-of-state tourists to self-isolate, citing data that about one in 10 of New Mexico’s spiking COVID-19 cases comes from visitors.

Enforcing the orders is proving difficult, given the lack of a national plan, police reluctance to take on the massive task, and Americans’ penchant for driving hundreds or thousands of miles to vacation, even in a pandemic.

A U.S. road trip this summer means navigating through a patchwork of quarantine regulations across various states, most of them voluntary.

New York, New Jersey and Connecticut require travelers from 19 states with high COVID-19 infection rates to self-quarantine for two weeks upon arrival. New York imposes fines.

Hard-hit Florida requires travelers from those three states to self-isolate for 14 days whether arriving by plane or car, or face a $500 fine.

Kansas, Maine, Massachusetts, Pennsylvania and Vermont all have varying self-isolation rules.

‘TAKING AWAY OUR LIBERTY’

New Mexico published newspaper ads in neighboring Arizona and Texas, states respectively reporting 27% and 18% positive coronavirus test rates, urging their residents not to visit. Health experts consider a 5% rate to be worrisome.

But tourists keep coming.

“I think it’s bullshit. They’re saying the masks should work, so why should you be quarantined?” said Chris Fry, 59, a feed company manager from Dimmitt, Texas, staying in his cabin near Red River and stopping in town for ice before going fishing.

A 45-minute drive south in Taos Plaza, Louisiana tourist Christy Brasiel was frustrated the historic Native American community was closed to visitors and compared Lujan Grisham’s rules to “communism or socialism.”

“They’re taking away our liberty,” said Brasiel, 49, staying in an Airbnb rental to avoid her voluntary quarantine order enforced by local hotels that turn away out-of-state visitors.

As in cities across New Mexico, police in Red River have yet to issue citations for non-compliance to COVID-19 rules, said Mayor Linda Calhoun, a Republican, adding that she is encouraging businesses to require masks.

“We live off of tourists, that’s all we have, so it’s very difficult for us to enforce the order,” Calhoun said of the quarantine rule in her town nicknamed “Little Texas” for the number of visitors from that state.

Many locals in Taos County, where COVID-19 cases have doubled in the last month, are dismayed by the rule breaking.

“It doesn’t make any sense to be so selfish,” said lawyer Maureen Moore, 67.

“WE DON’T WANT YOU HERE”

Only three weeks ago, as outbreaks raged across the U.S. Sunbelt, New Mexico reported stable or declining daily cases.

A poor state with limited hospital capacity, New Mexico used early, tough restrictions to curb the pandemic.

But with its positive test rate rising above 4%, Lujan Grisham has scolded New Mexicans for letting down their guard since she eased restrictions on June 1, and on Monday re-closed indoor restaurant dining.

On a shortlist as a running mate to presumptive Democratic presidential nominee Joe Biden, Lujan Grisham has also rounded on tourism, the state’s second-largest industry.

“We don’t want you here now,” she told potential visitors in a July 9 press briefing, taking special aim at Texans. “I want you to stay in Texas.”

Lujan Grisham said New Mexico State Police would “aggressively” enforce her quarantine and mask orders. The force has handed out 13 verbal warnings for mask violations but none for quarantine non-compliance, a spokeswoman said on Monday.

The rules are piling pandemic pain on businesses in the state. Standing outside his Red River supermarket, business owner Ted Calhoun said Lujan Grisham had gone too far.

“Ordering visitors to do a 14-day quarantine is killing the tourist industry of New Mexico,” said Calhoun, the mayor’s husband.

(Reporting by Andrew Hay in Red River, New Mexico; editing by Bill Tarrant, Tom Brown and Alistair Bell)