UK COVID-19 variant has significantly higher death rate, study finds

By Kate Kelland

LONDON (Reuters) – A highly infectious variant of COVID-19 that has spread around the world since it was first discovered in Britain late last year is between 30% and 100% more deadly than previous dominant variants, researchers said on Wednesday.

In a study that compared death rates among people in Britain infected with the new SARS-CoV-2 variant – known as B.1.1.7 – against those infected with other variants of the COVID-19-causing virus, scientists said the new variant’s mortality rate was “significantly higher”.

The B.1.1.7 variant was first detected in Britain in September 2020, and has since also been found in more than 100 other countries.

It has 23 mutations in its genetic code – a relatively high number – and some of them have made it far more easily spread. Scientists say it is about 40%-70% more transmissible than previous dominant variants that were circulating.

In the UK study, published in the British Medical Journal on Wednesday, infection with the new variant led to 227 deaths in a sample of 54,906 COVID-19 patients, compared with 141 among the same number of patients infected with other variants.

“Coupled with its ability to spread rapidly, this makes B.1.1.7 a threat that should be taken seriously,” said Robert Challen, a researcher at Exeter University who co-led the research.

Independent experts said this study’s findings add to previous preliminary evidence linking infection with the B.1.1.7 virus variant with an increased risk of dying from COVID-19.

Initial findings from the study were presented to the UK government earlier this year, along with other research, by experts on its New and Emerging Respiratory Virus Threats Advisory Group, or NERVTAG, panel.

Lawrence Young, a virologist and professor of molecular oncology at Warwick University, said the precise mechanisms behind the higher death rate of the B.1.1.7 variant were still not clear, but “could be related to higher levels of virus replication as well as increased transmissibility”.

He warned that the UK variant was likely fueling a recent surge in infections across Europe.

(Reporting by Kate Kelland; Editing by Pravin Char and Bernadette Baum)

U.S. lawmakers ask Blinken for briefing on Nord Stream 2 natgas pipeline

By Timothy Gardner

WASHINGTON (Reuters) – Several U.S. Representatives on Wednesday raised pressure on the State Department to share plans on potential sanctions on the Nord Stream 2 natural gas pipeline Russia is racing to finish to take fuel to Europe.

“If completed, Nord Stream 2 would enable the Putin regime to further weaponize Russia’s energy resources to exert political pressure throughout Europe,” two Republicans including Michael McCaul, and two Democrats including Marcy Kaptur, wrote in a letter to Secretary of State Antony Blinken.

U.S. representatives and senators have said that the Biden administration has missed a deadline of Feb. 16 to issue Congress a report required by recently passed law on companies helping Russia’s state energy company Gazprom lay pipeline, insure vessels, and certify construction work.

Several companies, including Zurich Insurance Group have already left fearing sanctions and companies listed in report could drop out of the project, making completion difficult.

Nord Stream 2 is more than 90% complete but requires additional tricky work in deep waters of the Baltic Sea off Denmark. The pipeline would bypass Ukraine, through which Russia has sent gas to Europe for decades, depriving it of lucrative transit fees and potentially undermining its struggle against Russian aggression.

The representatives asked Blinken for a briefing with State Department officials to inform them of the status of the report and their assessment of possible sanctionable activity of vessels believed to be helping to finish the project.

President Joe Biden believes the $11 billion pipeline, which would double the existing capacity of the Nord Stream system to take gas undersea to Germany, is a “bad deal for Europe” according to his press secretary Jen Psaki.

State Department spokesman Ned Price told reporters last week that “sanctions are only one” of many tools and that the department will work closely with allies and partners to reinforce European energy security and to safeguard against “predatory behavior”. The department did not immediately respond to a request about the requested briefing.

The representatives said the briefing should include details on “any proposals offered to the Biden administration on the future of the pipeline that aim to persuade the administration to forego or weaken the mandatory sanctions,” apparently referring to any talks between Washington and Germany for a deal on the project.

Gazprom insists the project will be completed in 2021.

(Reporting by Timothy Gardner; Editing by Marguerita Choy)

In first for Europe, Iran envoy sentenced to 20-year prison term over bomb plot

By Clement Rossignol and Robin Emmott

ANTWERP, Belgium (Reuters) – An Iranian diplomat accused of planning to bomb a meeting of an exiled opposition group was sentenced to 20 years in prison on Thursday in the first trial of an Iranian official for suspected terrorism in Europe since Iran’s 1979 revolution.

Assadolah Assadi was found guilty of attempted terrorism after a foiled plot to bomb a rally of the National Council of Resistance of Iran (NCRI) near Paris in June 2018, Belgian prosecution lawyers and civil parties to the prosecution said.

The third counsellor at Iran’s embassy in Vienna, he was arrested in Germany before being transferred to Belgium for trial. French officials said he was running an Iranian state intelligence network and was acting on orders from Tehran.

Assadi did not attend his hearings, which were held behind closed doors under high security, and neither he nor his lawyer have commented.

In March, Assadi warned authorities of possible retaliation by unidentified groups if he was found guilty, according to a police document obtained by Reuters. The courtroom was heavily guarded, with armored vehicles outside and police helicopters overhead.

In a statement carried by Iranian state television, Foreign Ministry spokesman Saeed Khatibzadeh said: “Unfortunately, Belgium and some European countries, under the influence of the hostile atmosphere of a terrorist group, have taken such an illegal and unjustifiable action.

“Therefore,” he said, “they must be held accountable for the gross violation of the rights of our country’s diplomats.”

Prosecution lawyer Georges-Henri Beauthier said outside the court in Antwerp: “The ruling shows two things: A diplomat doesn’t have immunity for criminal acts…and the responsibility of the Iranian state in what could have been carnage.”

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Investigators assessed that Assadi brought the explosives for the plot with him on a commercial flight to Austria from Iran, according to Belgium’s federal prosecutor.

Then-U.S. President Donald Trump’s lawyer Rudy Giuliani gave the keynote address at the rally, which was attended by diplomats from many countries.

The ruling came at a sensitive time for Western relations with Iran. New U.S. President Joe Biden is considering whether to lift economic sanctions on Iran re-imposed by Trump and rejoin fellow world powers in the historic 2015 accord with the Islamic Republic aimed at containing its nuclear program.

While the European Union has imposed human rights sanctions on Iranian individuals, Brussels has sought closer diplomatic and business ties with Tehran.

But it says it cannot turn a blind eye to terrorism, including the two killings in the Netherlands and a failed assassination attempt in Denmark, blamed on Iran.

“This case is not an aberration but rather is part of a pattern of the Islamic Republic’s terrorism in Europe and around the world,” said Toby Dershowitz at the Foundation for Defense of Democracies, a nonpartisan think-tank in Washington D.C.

Three other Iranians were sentenced in the trial for their role as accomplices, with 15-, 17- and 18-year sentences handed down respectively by three judges who did not comment on Thursday. One of their lawyers said he would recommend an appeal, although it was not clear if Assadi would do so.

In an interview with Reuters, NCRI chief Maryam Rajavi called the ruling a turning point as it proved Iran was carrying out state-sponsored terrorism. She said the EU could not stand by without reacting even if some in the 27-nation bloc were pushing for more dialogue with Tehran.

“Silence and inaction would be the worst policy and embolden the regime in its behavior,” she said, speaking through an interpreter, calling for EU sanctions on key officials, including Foreign Minister Mohammad Javad Zarif, who heads up nuclear diplomacy with the major powers.

“The European Union and governments must hold the regime accountable,” Rajavi said.

The EU declined to comment. French officials did not immediately respond to request for comment.

The Islamic Republic has repeatedly dismissed the charges, calling the attack allegations a “false flag” stunt by the NCRI, which it considers a terrorist group.

(Reporting by Clement Rossignol in Antwerp and Robin Emmott in Brussels with additional reporting by John Irish in Paris and Parisa Hafezi in Dubai; Editing by Marine Strauss, Philippa Fletcher and Mark Heinrich)

Second year of pandemic ‘could even be tougher’: WHO’s Ryan

GENEVA (Reuters) – The second year of the COVID-19 pandemic may be tougher than the first given how the new coronavirus is spreading, especially in the northern hemisphere as more infectious variants circulate, the World Health Organization (WHO) said on Wednesday.

“We are going into a second year of this, it could even be tougher given the transmission dynamics and some of the issues that we are seeing,” Mike Ryan, the WHO’s top emergencies official, said during an event on social media.

The worldwide death toll is approaching 2 million people since the pandemic began, with 91.5 million people infected.

The WHO, in its latest epidemiological update issued overnight, said after two weeks of fewer cases being reported, some five million new cases were reported last week, the likely result of a letdown of defenses during the holiday season in which people – and the virus – came together.

“Certainly in the northern hemisphere, particularly in Europe and North America we have seen that sort of perfect storm of the season – coldness, people going inside, increased social mixing and a combination of factors that have driven increased transmission in many, many countries,” Ryan said.

Maria Van Kerkhove, WHO’s technical lead for COVID-19, warned: “After the holidays, in some countries the situation will get a lot worse before it gets better.”

Amid growing fears of the more contagious coronavirus variant first detected in Britain but now entrenched worldwide, governments across Europe on Wednesday announced tighter, longer coronavirus restrictions.

That includes home-office requirements and store closures in Switzerland, an extended Italian COVID-19 state of emergency, and German efforts to further reduce contacts between people blamed for failed efforts, so far, to get the coronavirus under control.

“I worry that we will remain in this pattern of peak and trough and peak and trough, and we can do better,” Van Kerkhove said.

She called for maintaining physical distancing, adding: “The further, the better…but make sure that you keep that distance from people outside your immediate household.”

(Reporting by Stephanie Nebehay in Geneva and John Miller in Zurich; editing by Mark Heinrich)

Europe extends and tightens lockdowns, with fingers crossed for vaccines

By Claudia Cristoferi and John Revill

ROME/ZURICH (Reuters) – Governments across Europe announced tighter and longer coronavirus lockdowns and curbs on Wednesday amid fears of a fast-spreading variant first detected in Britain, with vaccinations not expected to help much until the spring.

Vaccines are being rolled out across the continent, but not as quickly as many countries had wished, and the effects are not expected until inoculations are widespread among the population.

Italy will extend its COVID-19 state of emergency to the end of April, Health Minister Roberto Speranza said as infections show no sign of abating.

Switzerland announced tighter measures to tackle new variants of the COVID-19 virus and extended the closure of restaurants, cultural and sport sites by five weeks to run until the end of February.

Germany is also likely to have to extend COVID-19 curbs into February, Health Minister Jens Spahn said, stressing the need to further reduce contacts to fend off the more infectious variant first identified in Britain.

The German cabinet approved stricter entry controls to require people arriving from countries with high caseloads or where the more virulent variant is circulating to take coronavirus tests.

Chancellor Angela Merkel told a meeting of lawmakers on Tuesday that the coming 8 to 10 weeks would be very hard if the more infectious variant spread to Germany, according to a participant at the meeting.

Health Minister Spahn told Deutschlandfunk radio it would take another two or three months before the vaccination campaign really started to help.

The Dutch government said late on Tuesday it would extend the lockdown, including the closure of schools and shops, by at least three weeks until Feb. 9.

“This decision does not come as a surprise, but it is an incredible disappointment,” Prime Minister Mark Rutte told a news conference, adding that the threat posed by the new variant was “very, very worrying”.

He said the government was considering imposing a curfew, but was reluctant and had sought outside advice before deciding on such severe restrictions.

In France, President Emmanuel Macron was discussing possible tighter rules with senior ministers. A nationwide curfew could be brought forward to 6 p.m. from 8 p.m., as has already happened in parts of the country, French media reported.

The French government’s top scientific adviser said new restrictions were needed in light of the variant first detected in Britain, adding that if vaccines were more widely accepted the crisis could be over by September.

“The coming three months will be difficult, the situation will slightly improve during the spring but should really get better at the end of the summer,” Jean-François Delfraissy told franceinfo radio.

In Switzerland, officials cancelled the Lauberhorn World Cup downhill race, out of fear that the new variant – brought in by what health authorities said was a single British tourist – was spreading now spreading rapidly among locals.

At least 60 people have tested positive in the Alpine resort of Wengen in the last four weeks.

Switzerland, which has so far taken a lighter touch to restricting business and public life than its neighbors, said it will close shops selling non-essential supplies from Monday.

It also ordered companies to require that employees work from home where possible. The country also eased rules on allowing pandemic-hit businesses to apply for state financial aid in hardship cases.

There was more optimistic news from Poland, where COVID-19 case numbers have stabilized after surging in the autumn.

“I hope that in two to three weeks the restrictions will be a little smaller, the vaccine will work,” Poland’s Finance Minister Tadeusz Koscinski said in an interview for Money.pl.

“Some restrictions will remain for quite a long time, but I think that 80% of these restrictions will start to disappear at the turn of the first and second quarter.”

(Reporting by Anthony Deutsch and Bart Meijer in Amsterdam, John Miller in Zurich, Benoit Van Overstraeten in Paris, Sabine Siebold and Hans-Edzard Busemann in Berlin, Pawel Florkiewicz in Warsaw, writing by Emma Thomasson; editing by Philippa Fletcher and Nick Macfie)

Europe crosses 500,000 COVID-19 deaths as new variant spreads

By Anurag Maan and Shaina Ahluwalia

(Reuters) – Europe became the first region worldwide to cross 500,000 COVID-19 deaths on Tuesday, according to a Reuters tally, as a new variant of the coronavirus discovered in Britain threatened the region’s prevention measures to curb the pandemic.

Reports of the mutated variant out of England prompted a pre-Christmas lockdown and have forced dozens of countries to close their borders to British travelers this week.

Italy, the nation with the highest death toll in Europe, on Sunday detected a patient infected with the new variant as have Denmark and France.

To curb the spread, European countries are considering screening passengers on flights from UK and obligating quarantine for travelers upon arrival.

Earlier this month, the United Kingdom became the first nation to approve the Pfizer Inc – BioNTech vaccine followed by the United States, European Union and other countries.

Europe has reported about 30% of the global COVID-19 fatalities and cases so far, according to a Reuters tally.

Europe’s death toll has accelerated in recent months. Since the first COVID-19 death was reported in France in February, it took eight months for the region to reach 250,000 deaths. It took only 60 days for the region to go from 250,000 to 500,000 deaths.

France, Spain, Italy, the United Kingdom and Russia have reported hundreds of deaths a day and the five countries account for almost 60% of the region’s total fatalities.

Globally there have been 77.52 million cases and 1.71 million deaths, according to a Reuters tally.

(Reporting by Anurag Maan and Shaina Ahluwalia in Bengaluru; Editing by Lisa Shumaker)

Moderna says UK deal will supply COVID-19 vaccine from March

(Reuters) – Moderna Inc confirmed on Tuesday it had agreed to supply its COVID-19 vaccine candidate, mRNA-1273, to the United Kingdom starting from the beginning of March, as long as it succeeds in gaining local regulatory approval.

The company’s statement did not disclose other terms of the agreement, including the number of doses it agreed to supply.

UK Health Minister Matt Hancock told a news conference on Monday that the deal would see the U.S. startup, one of two vaccine makers who have so far published positive data on final-stage trials, supply five million doses from next spring.

Moderna on Monday said mRNA-1273 was 94.5% effective in preventing COVID-19 based on interim data from its late-stage clinical trial.

Britain’s Medicines and Healthcare products Regulatory Agency (MHRA) in October started a real-time review of the vaccine candidate, a process which allows for a faster approval of a treatment.

The company on Tuesday also said it was on track to deliver about 500 million doses per year and possibly up to 1 billion doses per year, beginning in 2021.

It has tied up with manufacturing partners Lonza of Switzerland and ROVI of Spain, for manufacturing and fill-finish outside of the United States, to supply the vaccine to Europe and other countries outside U.S.

(Reporting by Manojna Maddipatla in Bengaluru; Editing by Krishna Chandra Eluri and Patrick Graham)

Moderna vaccine is second to exceed expectations; mutated virus may be more vulnerable to new vaccines

By Nancy Lapid

(Reuters) – The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

Vaccine from Moderna is second to exceed expectations in pivotal trial

Moderna Inc’s experimental vaccine was 94.5% effective in preventing COVID-19 based on interim data from a late-stage trial, the company said on Monday. That followed last week’s news that Pfizer Inc’s vaccine was also more than 90% effective based on initial data. Pending more safety data and regulatory review, the United States could have two vaccines authorized for emergency use in December. Both vaccines employ synthetic messenger RNA (mRNA), which coaxes cells to make certain virus proteins that the immune system sees as a threat and mounts a response against. Moderna’s trial involved 30,000 racially diverse U.S. adults, including people at high risk for severe COVID-19. Only five of the 95 COVID-19 cases in the initial analysis occurred in participants who received the vaccine, while the rest had received a placebo. The vaccine, administered in two shots 28 days apart, also appeared to prevent cases of severe COVID-19. Side effects, largely occurring after the second shot, included muscle aches, fever, headache and redness at the injection site. Moderna’s vaccine does not need ultra-cold storage like Pfizer’s, making it easier to distribute. Moderna expects it to be stable at normal refrigerator temperatures of 2 to 8 degrees Celsius (36 to 48°F) for 30 days and can be stored for up to 6 months at -20C.

Mutated virus may be more vulnerable to new vaccines

The mutated form of the new coronavirus that is now the most common strain worldwide is more infectious but may also be more vulnerable to vaccines under development, new research suggests. In experiments reported on Thursday in Science, researchers saw that the newer strain, which originated in Europe, is more efficient at infecting airway cells and at making copies of itself, although it does not appear to produce more severe illness. The D614G mutation causes a “flap” to open on the tip of a spike on the surface of the virus, improving its ability to break into cells, but also creating a pathway for antibodies in vaccines to enter the virus and disable it, the researchers explained in a statement. New SARS-CoV-2 mutations are continually emerging, “like the recently discovered mink SARS-CoV-2 cluster 5 variant in Denmark that also encodes D614G,” coauthor Ralph Baric of the University of North Carolina School of Medicine said in the statement. “We must continue to track and understand the consequences of these new mutations on disease severity, transmission, host range and vulnerability to vaccine-induced immunity,” he added.

Paper forms pose coronavirus risk for lab staff

When laboratory personnel are processing COVID-19 tests, there is a small risk that the paper forms accompanying the specimens can be contaminated with the new coronavirus, a new report cautions. Researchers at the Birmingham Public Health Laboratory in the UK analyzed randomly selected paper forms and specimen packaging during a period when the team was processing about 700 COVID-19 tests daily. Of the 37 items they tested, one piece of paperwork carried genetic material from the coronavirus. The form had come from a low-risk hospital ward, and the specimen from the patient was negative for the virus, “indicating contamination may be occurring as a result of environmental or healthcare worker contamination,” the researchers wrote on Thursday in the Journal of Hospital Infection. They call for “stringent laboratory practices” – hand hygiene, appropriate personal protective equipment – and “use of electronic test requesting where possible.”

(Reporting by Nancy Lapid, Julie Steenhuysen and Michael Erman; Editing by Bill Berkrot)

Europe COVID death toll tops 300,000 as winter looms and infections surge

By Shaina Ahluwalia, Anurag Maan and Roshan Abraham

(Reuters) – More than 300,000 people have died of COVID-19 across Europe, according to a Reuters tally on Tuesday, and authorities fear that fatalities and infections will continue to rise as the region heads into winter despite hopes for a new vaccine.

With just 10% of the world’s population, Europe accounts for almost a quarter of the 1.2 million deaths globally, and even its well-equipped hospitals are feeling the strain.

After achieving a measure of control over the pandemic with broad lockdowns earlier this year, case numbers have surged since the summer and governments have ordered a second series of restrictions to limit social contacts.

In all, Europe has reported some 12.8 million cases and about 300,114 deaths. Over the past week, it has seen 280,000 cases a day, up 10% from the week earlier, representing just over half of all new infections reported globally.

Hopes have been raised by Pfizer Inc’s announcement of a potentially effective new vaccine, but it is not expected to be generally available before 2021 and health systems will have to cope with the winter months unaided.

Britain, which has imposed a fresh lockdown in England, has the highest death toll in Europe at around 49,000, and health experts have warned that with a current average of more than 20,000 cases daily, the country will exceed its “worst case” scenario of 80,000 deaths.

France, Spain, Italy and Russia have also reported hundreds of deaths a day and together, the five countries account for almost three quarters of the total fatalities.

Already facing the prospect of a wave of job losses and business failures, governments across the region have been forced to order control measures including local curfews, closing non-essential shops and restricting movement.

France, the worst-affected country in the EU, has registered more than 48,700 infections per day over the past week and the Paris region’s health authority said last week that 92% of its ICU capacity was occupied.

Facing similar pressures, Belgian and Dutch hospitals have been forced to send some severely ill patients to Germany.

In Italy, which became a global symbol of the crisis when army trucks were used to transport the dead during the early months of the pandemic, daily average new cases are at a peak at more than 32,500. Deaths have been rising by more than 320 per day over the past three weeks.

While the new vaccine being developed by Pfizer and German partner BioNTech will take time to arrive, authorities are hoping that once winter is passed, it will stem further outbreaks next year.

Citi Private Bank analysts described the news as “the first major advance toward a Post-COVID world economy”.

“More than any fiscal spending package or central bank lending program, a healthcare solution to COVID has the greatest potential to restore economic activity to its full potential…” it said in a note.

European Commission President Ursula von der Leyen on Monday said the European Union would soon sign a contract for 300 million doses of the vaccine, just hours after the drugmaker announced promising late-stage trials.

Yet health experts cautioned that the vaccine, should it be approved, was no silver bullet – not least because the genetic material it’s made from needs to be stored at temperatures of minus 70 degrees Celsius (-94 F) or below.

Such requirements pose a challenge for countries in Asia, as well as Africa and Latin America, where intense heat is often compounded by poor infrastructure.

(Reporting by Anurag Maan, Shaina Ahluwalia, Chaithra J and Roshan Abraham in Bengaluru, Sujata Rao-Coverley in London; editing by Jane Wardell, James Mackenzie, Nick Macfie and Mike Collett-White)

Pandemic takes center stage in holiday shopping ad campaigns

By Sheila Dang

(Reuters) – After spending the summer convincing consumers to take socially distanced breaks from grim reality, advertisers are now returning to the pandemic as the central focus in holiday shopping campaigns launching this month.

U.S. companies from carmakers to retailers are under pressure to make the shopping season a success after retail sales crashed 21% earlier this year as millions of Americans lost jobs and cut their budgets. They face the challenge of convincing consumers to open their wallets for the holidays even as the coronavirus pandemic rages anew across the United States and Europe.

As new campaigns roll out, brands feel it is their responsibility to inspire optimism for the coming year, but also empathize with “the hurt that people have,” said Jason Schragger, chief creative officer at ad agency Saatchi & Saatchi.

Carmaker Lexus’ iconic “December to Remember” campaign, which features cars wrapped in giant red bows on picturesque snowy driveways, will focus on the different role that driveways have played this year, as people sought ways to celebrate birthdays, anniversaries and other milestones despite stay-at-home orders.

New TV commercials launching on Monday feature family and friends doing a drive-by graduation party in their Lexus vehicles as a student in a cap and gown waves from her driveway. In another, a man greets his children and grandkids from a distance as they drive by, waving a homemade “Happy Birthday, Grandpa” sign.

“We wanted to make sure we weren’t showing large gatherings of people,” said Lisa Materazzo, vice president of marketing at Lexus, owned by Toyota Motor Corp. “But it’s nice to have a live interaction, and that can happen when you’re safe in the car and waving from the driveway.”

Staying connected during the pandemic is the message behind ads for the department store Macy’s, whose window displays and Santa land attraction have been hallmarks of the holidays since the late 19th century.

At a time when flying home or hosting big family gatherings can be dangerous, Macy’s Inc is focusing on how finding and giving the perfect gift plays an even bigger role in connecting with people you can not see in person this year, according to Macy’s chief customer officer Rich Lennox.

A similar theme underpins Etsy’s commercial, in which a woman who longs to see her grandson opens a gift of a handmade doll that matches a picture he had drawn.

“You’re supposed to hug it when you can’t see us,” her grandson said over a video call while holding up the drawing.

PANDEMIC ADJUSTMENTS

Apparel retailer H&M has taken the pandemic-themed ad campaign a step further by changing how commercials are produced in keeping with the times.

The company will lean on influencers working from home to create content, and plans to provide them with outfits and holiday prop kits so they can take festive photos on their own, said Mario Moreno, H&M USA’s head of marketing.

Toy maker Mattel, which has targeted young fans directly on kids’ TV shows, is directing some marketing messages to parents this season.

The owner of the Barbie and Fisher-Price brands will craft digital and social media ads that address the struggle parents have with keeping their kids entertained and engaged after months of schooling from home, said Jason Horowitz, senior vice president of U.S. marketing at Mattel.

The ads will focus on gifts that can offer hours of playtime and mental stimulation while cooped up inside, such as a Thomas & Friends toy that lets kids make-believe that they are taking a trip from their living room, he said.

Expect optimism with a dose of reality at this dark time, ad executives said.

“There’s a lot of 2020 we want to leave behind,” Materazzo said. “But there are nuggets worth celebrating.”

(Reporting by Sheila Dang; Editing by Kenneth Li and Daniel Wallis)