Trial wraps up for pharmacist in deadly U.S. meningitis outbreak

Trial wraps up for pharmacist in deadly U.S. meningitis outbreak

By Nate Raymond

BOSTON (Reuters) – Closing arguments are set for Friday in the trial of a Massachusetts pharmacist accused of murder and fraud for his role in a 2012 fungal meningitis outbreak that killed 76 people and sickened hundreds more across the United States.

Federal prosecutors in Boston contend that Glenn Chin, a former supervisory pharmacist at New England Compounding Center, cut corners while overseeing the production of drugs the company produced in filthy conditions.

Those drugs included steroids tainted with mold that were shipped out to healthcare facilities nationally and then injected into patients, leading to an outbreak that sickened 778 people nationally, prosecutors said.

They said that Chin, 49, recklessly failed to ensure the compounding pharmacy’s drugs were produced in sanitary conditions to keep up with demand from hospitals for its products.

Prosecutors claim Chin directed staff in NECC’s so-called clean rooms where the drugs were made, to skip cleaning, despite the presence of insects, mice and mold.

Chin has pleaded not guilty to charges including racketeering and mail fraud. He faces up to life in prison if he is convicted of second-degree murder charges brought under racketeering law.

Defense lawyers counter that Chin did nothing to kill the 25 people who are the subject of those murder allegations and say blame instead lies with Barry Cadden, NECC’s co-founder and former president.

They say that Cadden directed the corner-cutting at NECC, and note that at his trial earlier this year, prosecutors said people died because Cadden decided to put profits before patient safety.

Cadden was sentenced in June to nine years in prison after he was found guilty of racketeering and fraud charges but cleared of murder.

Lesser charges were filed against 12 other people. Three have pleaded guilty, while a federal judge dismissed charges against two defendants in October 2016. Charges remain pending against the other seven.

(Reporting by Nate Raymond; Editing by Scott Malone and Bernadette Baum)

Cholera claims unborn children as epidemic spreads Yemen misery

Children wait to be treated at a cholera treatment center in Sanaa, Yemen May 15, 2017. Picture taken May 15, 2017.

By Abduljabbar Zeyad

HODEIDAH, Yemen (Reuters) – One of the latest victims of the cholera epidemic that has killed more than 2,000 people in Yemen had yet to even take her first breath.

Her mother Safaa Issa Kaheel, then nine months pregnant, was brought into a crowded clinic in the Western port city of Hodeidah by her husband, who had to borrow the travel fare from a neighbor. “My stomach started hurting more and more,” said Kaheel, 37, a hydrating drip hooked into her arm.

Once there, she was referred by nurse Hayam al-Shamaa for an ultrasound scan which showed her baby had died of dehydration – one of 15 to perish in the womb due to cholera in September and October, according to doctors at the city’s Thawra hospital.

“I felt like death,” Kaheel said, her voice strained. “Thank god I survived the (delivery), but my diarrhea hasn’t stopped.”

The Red Cross has warned that cholera, a diarrheal disease that has been eradicated in most developed countries, could infect a million people in Yemen by the end of the year.

Two and a half years of war have sapped Yemen of the money and medical facilities it needs to battle the contagion, to which aid agencies and medics say the poor, the starving, the pregnant and the young are most vulnerable.

The cholera ward is full of children – some writhing in agony, others eerily still. The blanket over one boy too weak to move rises and falls with his shallow breathing.

Save the Children said in August that children under 15 represent nearly half of new cases and a third of deaths, with malnourished children more than six times more likely to die of cholera than well-fed ones.

Millions of Yemenis are struggling to find food and the baking desert plains around Hodeidah are hotspots both of hunger and sickness.

Yemen’s war pits the armed Houthi movement against the internationally recognized government of President Abd-Rabbu Mansour Hadi, which is backed by a Saudi-led coalition that has launched thousands of air strikes to restore him to power.

At least 10,000 people have been killed in the conflict.

The country’s health sector has been badly battered while a struggle over the central bank has left public sector salaries for doctors and sanitation workers unpaid.

Soumaya Beltifa, spokesperson for the Red Cross in Sanaa, warned that a lack of funds and health personnel were blunting efforts to eradicate the disease, making it unlikely Yemen would be healthy again soon.

“The cholera epidemic has become a norm, leading to complacency in dealing with the disease, not only by civilians but also from the various (aid) organizations,” she warned.

 

Plague outbreak in Madagascar kills 20: WHO

NAIROBI (Reuters) – An outbreak of plague has killed 20 people in the space of a month in Madagascar, with a further 84 infected, the World Health Organisation (WHO) said on Friday.

Plague is mainly spread by flea-carrying rats. Humans bitten by an infected flea usually develop a bubonic form of plague, which swells lymph nodes and can be treated with antibiotics.

But the more dangerous pneumonic form invades the lungs and can kill a person within 24 hours if not treated. About half of the 104 known cases are pneumonic, the WHO said.

WHO spokesman Tarik Jasarevic told reporters in Geneva that areas affected included the capital Antananarivo and the port cities of Mahajenga and Toamasina.

The U.N. health agency said it feared that the outbreak could worsen because the season for plague, which is endemic in Madagascar, had only just begun, and runs until April. On average, 400 cases are reported each year.

“The overall risk of further spread at the national level is high,” WHO said in a statement.

(Reporting by Stephanie Nebehay in Geneva; writing by Elias Biryabarema; Editing by Kevin Liffey)

Yemen cholera cases could hit 1 million by year-end: Red Cross

Yemen cholera cases could hit 1 million by year-end: Red Cross

By Stephanie Nebehay

GENEVA (Reuters) – The humanitarian situation in Yemen is a “catastrophe”, and cholera cases could reach a million by the end of the year, the International Committee of the Red Cross said on Friday.

Warring parties in Yemen – including the western-backed Saudi-led coalition – are all using disproportionate force, leading to “very excessive” civilian casualties, said Alexandre Faite, the head of the Red Cross delegation in Yemen.

In addition, suspected cases of cholera have reached 750,000, with 2,119 deaths, Faite said, and the Red Cross expects at least 900,000 cases by the end of the year.

“The situation has really evolved in a very dramatic way and I think that it’s nothing short of a catastrophe,” Faite told a news briefing in Geneva.

Civil war in Yemen has killed more than 10,000 people since it began in March 2015. Control of the country is split between the Iran-aligned Houthis, who control much of northern Yemen, including the capital, Sanaa. Opposed to the Houthis are a Saudi-led coalition.

With the main port of Hodeidah damaged, the Red Cross brings medical aid, including insulin, into Yemen with occasional cargo planes to Sanaa. Other goods come by land convoys from Jordan and Oman and by ship from Jordan, Oman and Dubai.

A ship from Karachi with 500 metric tonnes of rice is now due on Oct 7 in Hodeidah, the first ICRC shipment there since early February.

Faite called on all sides to open Sanaa airport to commercial flights for essential aid supplies and to make progress toward allowing the Red Cross to visit prisoners of war.

“I don’t think political settlement is coming soon and I’m very worried that the extension of the conflict would lead to more problems,” Faite said.

“This is why humanitarian aid, access of essential goods should be there,” he said. “There is a bottleneck”.

Although the death rate for cholera victims has dropped to less than 0.3 percent, Faite said Yemen’s “health sector is really on its knees in Yemen … the health staff is on its knees as well because they are not paid.”

For the first time, the Red Cross is now providing health workers with food parcels, he said.

“In terms of access to even water, electricity, there isn’t a power grid in the main cities in Yemen. Without the ICRC and other organizations fixing (pumping stations) there wouldn’t be any running water in Sanaa,” he said.

(Reporting by Stephanie Nebehay; editing by John Stonestreet)

Floods, landslides kill more than 800 people across South Asia

People use a boat as they try to move to safer places along a flooded street in West Midnapore district, in West Bengal

By Ruma Paul and Zarir Husain

DHAKA/GUWAHATI, India (Reuters) – Widespread floods have killed more than 800 people and displaced over a million in India, Nepal and Bangladesh, with aid workers warning of severe food shortages and water-borne diseases as rains continue to lash the affected areas.

Seasonal monsoon rains, a lifeline for farmers across South Asia, typically cause loss of life and property every year between July and September, but officials say this year’s flooding is the worst in several years.

At least 115 people have died and more than 5.7 million are affected in Bangladesh as floods submerged more than a third of the low-lying and densely populated country.

“The water level has gradually dropped. The flood situation will improve if it does not rain upstream any further,” Sazzad Hossain, executive engineer of Bangladesh’s Flood Forecasting and Warning Center, told Reuters.

Reaz Ahmed, the director general of Bangladesh’s Disaster Management Department, said there are rising concerns about food shortages and the spread of disease.

“With the flood waters receding, there is a possibility of an epidemic. We fear the outbreak of water-borne diseases if clean water is not ensured soon,” Ahmed told Reuters.

With some rivers running above danger levels, 225 bridges have been damaged in Bangladesh, disrupting food and medicine supplies to people displaced from their homes, said aid workers.

In the Indian state of Assam bordering Bangladesh, at least 180 people have been killed in the past few weeks.

“With the floods washing away everything… there is not even a trace of our small thatched hut,” said Lakshmi Das, a mother of three, living in Kaliabor, Assam.

“We do not even have a second pair of clothes to wear. The government is not providing any aid.”

Villagers use a boat as they row past partially submerged houses at a flood-affected village in Morigaon district in Assam,

Villagers use a boat as they row past partially submerged houses at a flood-affected village in Morigaon district in Assam, July 14, 2017. REUTERS/Anuwar Hazarika

Torrential rains have also hit the northeastern states of Arunachal Pradesh, Nagaland and Manipur, killing at least 30 people.

Flood waters of the Brahmaputra river had earlier in July submerged the Kaziranga wildlife sanctuary in Assam. The floods have since killed more than 350 animals, including 24 endangered one-horned rhinoceros, five elephants and a tiger.

“We are facing a wildlife disaster,” Assam Forest Minister Pramila Rani Brahma told Reuters.

Meanwhile, in the eastern state of Bihar, at least 253 people lost their lives where incessant rains washed away crops, destroyed roads and disrupted power supplies.

A senior official in Bihar’s disaster management department, Anirudh Kumar, said nearly half a million people have been provided with shelter.

In Nepal, 141 people were confirmed dead, while thousands of survivors returned to their semi-destroyed homes.

“Their homes are in a state of total destruction,” said Francis Markus from International Federation of Red Cross and Red Crescent Societies.

 

(Reporting by Gopal Sharma in Kathmandu, Zarir Husain in Assam, Jatindra Das in Bhubaneswar, Ruma Paul in Dhaka; Writing by Rupam Jain in New Delhi,; Editing by Tommy Wilkes and Sherry Jacob-Phillips)

 

270 bodies recovered from Sierra Leone mudslide: mayor

270 bodies recovered from Sierra Leone mudslide: mayor

By Christo Johnson and Umaru Fofana

FREETOWN (Reuters) – Rescue workers have recovered 270 bodies so far from a mudslide in the outskirts of Sierra Leone’s capital Freetown, the mayor said on Tuesday, as rescue operations continued and morgues struggled to find space for all the dead.

President Ernest Bai Koroma urged residents of Regent and other flooded areas around Freetown to evacuate immediately so that military personnel and other rescue workers could continue to search for survivors that might be buried underneath debris.

Dozens of houses were covered in mud when a mountainside collapsed in the town of Regent on Monday morning, one of the deadliest natural disasters in Africa in recent years.

“We have a total of 270 corpses which we are now preparing for burial,” Freetown mayor Sam Gibson told reporters outside city hall.

Bodies have continued to arrive at the city’s central morgue. Corpses are lying on the floor and on the ground outside because the morgue is overloaded, a Reuters witness said.

“Our problem here is space. We are trying to separate, quantify, and examine quickly and then we will issue death certificates before the burial,” said Owiz Koroma, head of the morgue.

He did not have an updated death toll but said: “It’s in the hundreds, hundreds!”

270 bodies recovered from Sierra Leone mudslide: mayor

The surface of a hillside is pictured after a mudslide in the mountain town of Regent, Sierra Leone August 14, 2017. REUTERS/Ernest Henry

FEAR OF DISEASE

Sierra Red Cross Society spokesman Abu Bakarr Tarawallie said by phone he estimated that at least 3,000 people were homeless and in need of shelter, medical assistance and food. The Red Cross said another 600 were missing.

“We are also fearful of outbreaks of diseases such as cholera and typhoid,” he told the Thomson Reuters Foundation from Freetown. “We can only hope that this does not happen.”

Contaminated water and water-logging often lead to potentially deadly diseases like cholera and diarrhea after floods and mudslides.

Crowds of people gathered, waiting for news of missing family members.

“I’ve been looking for my aunt and her two children, but so far no word about them,” said Mohamed Jalloh, crying. He said he feared the worst.

President Koroma said in a television address on Monday evening that rescue centers had been set up around the capital to register and assist victims.

Bulldozers dug through mud and rubble at the foot of Mount Sugar Loaf, where many residents had been asleep when part of the mountainside collapsed. The government said a number of illegal buildings had been erected in the area.

(Writing by Nellie Peyton; additional reporting by Kieran Guilbert; Editing by Ralph Boulton)

Dengue outbreak kills 300 in Sri Lanka, hospitals at limit

A mosquito landing on a person. Courtesy of Pixabay

COLOMBO (Reuters) – An outbreak of dengue virus has killed around 300 people so far this year in Sri Lanka and hospitals are stretched to capacity, health officials said on Monday.

They blamed recent monsoon rains and floods that have left pools of stagnant water and rotting rain-soaked trash — ideal breeding sites for mosquitoes that carry the virus.

The International Federation of Red Cross and Red Crescent Societies is scaling up emergency assistance to Sri Lanka with the Sri Lanka Red Cross to help contain the outbreak.

“Dengue patients are streaming into overcrowded hospitals that are stretched beyond capacity and struggling to cope, particularly in the country’s hardest hit western province,” Red Cross/Red Crescent said in a statement.

According to the World Health Organization, dengue is one of the world’s fastest growing diseases, endemic in 100 countries, with as many as 390 million infections annually. Early detection and treatment save lives when infections are severe, particularly for young children.

The Sri Lankan government is struggling to control the virus, which causes flu-like symptoms and can develop into the deadly hemorrhagic dengue fever.

The ministry of health said the number of dengue infections has climbed above 100,000 since the start of 2017, with 296 deaths.

“Ongoing downpours and worsening sanitation conditions raise concerns the disease will continue to spread,” Red Cross/Red Crescent said.

Its assistance comes a week after Australia announced programs to help control dengue fever in Sri Lanka.

“Dengue is endemic here, but one reason for the dramatic rise in cases is that the virus currently spreading has evolved and people lack the immunity to fight off the new strain,” Novil Wijesekara, head of health at the Sri Lanka Red Cross said in a statement.

(Reporting by Ranga Sirilal and Shihar Aneez Editing by Jeremy Gaunt.)

Senator McCain diagnosed with aggressive brain cancer

FILE PHOTO: U.S. Senator John McCain attends a news conference at the Benjamin Franklin Library in Mexico City, Mexico December 20, 2016. REUTERS/Henry Romero/File Photo

By Patricia Zengerle

WASHINGTON (Reuters) – U.S. Senator John McCain, the 2008 Republican presidential nominee known for political independence during more than three decades in the Senate, has been diagnosed with an aggressive form of brain cancer, his office said on Wednesday.

The 80-year-old lawmaker and former Navy pilot, who was re-elected to a sixth Senate term in November, has been recovering at home in Arizona since undergoing surgery at the Mayo Clinic in Phoenix last Friday to remove a blood clot from above his left eye.

Tissue analysis since that procedure revealed that a brain tumor known as a glioblastoma was associated with the clot, his office said.

McCain’s doctors said he was recovering from surgery “amazingly well” and that his underlying health was excellent. Treatment options include a combination of chemotherapy and radiation.

However, glioblastoma is considered a grade IV tumor, the most malignant of gliomas. Medical experts said it can be very aggressive and spread into other parts of the brain quickly.

“It takes people’s lives almost uniformly … The tumor cells are very resistant to conventional therapy, such as radiation and chemotherapy. It’s a poor prognosis,” said Dr. Richard Ellenbogen, who chairs the Department of Neurological Surgery at the University of Washington.

McCain’s daughter, Meghan McCain, said the family was shocked by the diagnosis but that her father was the “most confident and calm” of them all as he prepared for a new battle against cancer.

McCain has had non-invasive melanomas removed at least three times. He also overcame injuries suffered as a prisoner of war in Vietnam, where he endured beatings and torture by his North Vietnamese captors.

Questions about McCain’s health arose during a recent Senate hearing when the lawmaker, normally a keen interrogator of witnesses, rambled during questioning of former FBI Director James Comey. His doctors told CNN on Wednesday, however, that he had no sign of neurological impairment before or during his surgery.

His fellow members of Congress rushed to offer tributes to McCain and wishes for his quick recovery. Known for an independent political streak, ready wit and strong opinions, McCain is one of the best-known and most popular U.S. lawmakers among his peers and the media.

Senator Lindsey Graham, a long-time friend, said McCain was “resolved and determined” when they spoke by telephone. “This disease has never had a more worthy opponent.”

While known as a fierce advocate for strong U.S. military action overseas, McCain also has a reputation for working with Democrats on issues from clamping down on campaign finance abuses to immigration reform. This week, McCain called for a bipartisan approach to overhauling the U.S. healthcare system.

‘GIVE IT HELL, JOHN’

“Senator John McCain has always been a fighter,” said President Donald Trump. “Get well soon.”

Former Democratic President Barack Obama, who defeated McCain for the White House in 2008, called McCain “an American hero and one of the bravest fighters I’ve ever known. Cancer doesn’t know what it’s up against. Give it hell, John.”

McCain was one of Congress’ most vocal critics of Obama’s foreign policy, but he has also raised questions about Trump, a fellow Republican.

McCain found himself to be a brief side issue in the race for the 2016 Republican presidential nomination when he criticized Trump, who responded by saying McCain was not a war hero because he had been captured by the Vietnamese.

Senate Majority Leader Mitch McConnell called McCain, the chairman of the Armed Services Committee, a hero and said he looked forward to having him back in Washington.

McCain, the son and grandson of admirals, was a U.S. Navy pilot. His plane was shot down over Vietnam in 1967 and he spent 5-1/2 years as a prisoner of war.

One of McCain’s proudest moments as a U.S. senator was working to pass legislation banning torture in 2015.

When he was offered release because of his father’s rank, McCain refused to be freed before those who had been held captive longer. He finally returned to the United States in 1973, with other prisoners of war.

McCain’s absence this week has complicated efforts by Trump and his fellow Republicans to repeal Obama’s Affordable Care Act, popularly known as Obamacare. McCain’s absence from Washington makes it difficult for McConnell to gather the 50 votes he needs in a chamber where the party holds only a 52-48-seat margin.

His absence could also complicate progress toward passing the annual National Defense Authorization Act, a $700 billion piece of legislation setting policy for the Department of Defense that must pass every year.

(Reporting by Patricia Zengerle; Additional reporting by Steve Holland, Richard Cowan and Yasmeen Abutaleb in Washington, Eric M. Johnson in Seattle and Dan Whitcomb in Los Angeles; Editing by Kieran Murray and Peter Cooney)

Cholera kills four in Kenyan capital since May, government shuts hotels

Cholera patients receive treatment and care inside a special ward at the Kenyatta National Hospital in Nairobi, Kenya July 19, 2017. REUTERS/Thomas Mukoya

By George Obulutsa

NAIROBI (Reuters) – A cholera outbreak in the Kenyan capital has killed four people since May and the government has shut down a three-star hotel and a popular restaurant there to control its spread, the health minister said on Wednesday.

At least 79 people with confirmed cases of cholera were being treated in various Nairobi hospitals and authorities were setting up 10 more treatment centers to cope with the outbreak, Cleopa Mailu, the minister, told a news conference.

“We have so far closed two hotels … and we shall continue to do so if there is evidence there is risk to the public,” Mailu said, after visiting some of the patients.

The government had ordered the immediate testing of about half a million people in the food handling business in the next 21 days, he said.

Mailu said local authorities in Nairobi would be required to repair all broken sewer lines, ensure all water vendors and their water sources were certified, and ban hawking of food.

“Some of them (measures) will not be pleasant,” he said.

Containing cholera in Nairobi is critical, given it is a major hub, not just in Kenya, but in the region.

Mailu said the Kenya Red Cross and UNICEF were also helping to contain the cholera, a diarrhoeal disease transmitted by infected food and water. It can kill within hours unless treated with intravenous fluids and antibiotics.

Kenya has suffered several waves of cholera since 1971, according to the World Health Organization. An outbreak in March last year killed 216 people with 13,000 hospitalized across the country.

Two ministers, Henry Rotich and Adan Mohamed, sought treatment with cholera-like symptoms after eating food during a government event in the capital last week, local newspapers reported.

Rotich’s ministry of finance said he did not wish to comment. Mohamed, who is industrialization minister, was not available immediately.

(Editing by Duncan Miriri and Richard Balmforth)

Chipotle to reopen Virginia restaurant after norovirus reports

FILE PHOTO - A Chipotle Mexican Grill is seen in Los Angeles, California, U.S. on April 25, 2016. REUTERS/Lucy Nicholson/File Photo

BOSTON (Reuters) – Chipotle Mexican Grill Inc said it will reopen a Virginia restaurant on Wednesday, two days after it was closed due to reports that several customers had fallen ill with suspected norovirus.

Shares of the restaurant chain tumbled more than 4 percent on Tuesday after Chipotle reported the closure. The former high-flying chain is still fighting to repair its reputation and resuscitate its sales after a string of high-profile food safety lapses in late 2015.

Chipotle voluntarily closed the restaurant in Sterling, Virginia, on Monday, according to a health official for the Loudoun County Public Health Department, which has jurisdiction over the restaurant, about 30 miles (48 km) northwest of Washington.

About 13 people became sick last week, according to a website that follows incidents of foodborne illness. Test results are still pending.

Chipotle stock, which traded well above $700 prior to 2015 reports linking the chain to outbreaks of E. coli, salmonella and norovirus, was off 1.4 percent at $369.56 on Wednesday.

“It is unfortunate that anyone became ill after visiting our restaurant, and when we learned of this issue, we took aggressive action to correct the problem and protect our customers,” Chipotle Chief Executive Officer Steve Ells said in a statement.

“While the restaurant was closed, multiple teams performed complete sanitization of all surfaces,” Ells said.

Norovirus, is the leading cause of illness and outbreaks from contaminated food in the United States, according to the Centers for Disease Control and Prevention.

It can spread from person to person, as well as through food prepared by an infected person. It often hits closed environments such as daycare centers, schools and cruise ships. Most outbreaks happen from November to April in the United States.

(Reporting by Lisa Baertlein in Boston; Editing by Jeffrey Benkoe)