New U.S. COVID cases fall for third week, deaths lowest since July

(Reuters) – New cases of COVID-19 in the United States fell for a third week in a row, dropping 15% last week to 347,000, the lowest weekly total since October, according to a Reuters analysis of state and county data.

Nearly a third of the country’s population has been fully vaccinated as of Sunday, and 44% has received at least one dose of a COVID-19 vaccine, according to the U.S. Centers for Disease Control and Prevention.

Michigan again led the states in new cases per capita, though new infections fell 26% last week compared with the previous seven days, the Reuters analysis showed. New cases also fell in Colorado and Minnesota, the states with the next highest rates of infection based on population.

Health officials have warned that more contagious variants of the coronavirus are still circulating, such as the B.1.1.7 variant first detected in the United Kingdom and partly responsible for the surge in Michigan.

In Oregon, where the B.1.1.7 variant is now the dominant strain, the governor last week placed nearly half the state’s counties in the extreme risk category for COVID-19, banning indoor dining and restricting capacity at other businesses.

Oregon reported a 1.2% rise in new cases last week to about 5,600, double the weekly cases seen in early April.

Nationally, deaths from COVID-19 fell 3% to 4,819 in the week ended May 2, the fewest deaths in a week since July.

The average number of COVID-19 patients in hospitals fell 8%, the first weekly decrease after rising or holding steady for four weeks.

Vaccinations fell for a second week in a row, dropping 12% after falling 14% in the previous week.

(Graphic by Chris Canipe, writing by Lisa Shumaker, editing by Tiffany Wu)

India’s vaccinations plummet as coronavirus infections soar

By Krishna N. Das

NEW DELHI (Reuters) -India’s daily COVID-19 shots have fallen sharply from an all-time high reached early last month as domestic companies struggle to boost supplies and imports are limited, even as the country fights the world’s worst surge in infections.

Daily inoculations have averaged 2.5 million since hitting a peak of 4.5 million on April 5. A quadrupling of coronavirus cases during the period has collapsed the public health system in many regions of the country.

India, with the world’s biggest vaccine making capacity, has partially or fully immunized only 12% of its 1.35 billion people, according to data from the government’s Co-Win.

Public forecasts by its only two current vaccine producers show their total monthly output of 70-80 million doses would increase only in two months or more, though the number of people eligible for vaccines has doubled to an estimated 800 million since May 1.

India on Saturday received 150,000 doses of Russia’s Sputnik V vaccine and the government said “millions of doses” more will come in.

Pfizer said on Monday it was in discussions with the Indian government seeking an “expedited approval pathway” for its vaccine.

“Unfortunately, our vaccine is not registered in India although our application was submitted months ago,” CEO Albert Bourla said.

“We are currently discussing with the Indian government an expedited approval pathway to make our Pfizer-BioNTech vaccine available for use in the country.”

Pfizer was the first company to seek emergency use authorization for its vaccine in India late last year. It withdrew its application in February after the drugs regulator sought a small, local safety study for the shot before considering its request.

But as cases surged, India said last month it would fast-track approval for some foreign shots, with companies now required to do a local trial within 30 days of approval, not before.

GlobalData analyst Prashant Khadayate said Pfizer will become a “vaccine of choice among people who can afford it” but that its need to be stored in ultra-low temperatures would be a challenge.

India has also invited Johnson & Johnson and Moderna to sell their vaccines to the country.

(Reporting by Krishna N. Das; Additional reporting by Manash Mishra; Editing by Tom Hogue and Nick Macfie)

EU aims to open up to foreign tourists this summer amidst COVID-19

By Gabriela Baczynska

BRUSSELS (Reuters) -The European Union’s executive has recommended easing COVID-19 travel restrictions next month to let foreign travelers from more countries enter the bloc, hoping to boost the stricken tourism industry this summer.

Under current restrictions, people from only seven countries, including Australia and Singapore, can enter the EU on holiday, regardless of whether they have been vaccinated but subject to tests or quarantine.

New proposals from the European Commission on Monday, but still requiring approval by the EU’s 27 member states, would allow in fully vaccinated foreign citizens and those from countries with a “good epidemiological situation”.

“Time to revive tourism industry and for cross-border friendships to rekindle – safely,” Commission President Ursula von der Leyen wrote on Twitter.

People arriving from Britain, Russia and a number of other countries would meet the new criteria, according to data provided by the Centre for Disease Control and Prevention (CDC). U.S. citizens would not currently do so.

“We want to have this done before the mass summer travel starts,” an EU official said.

EU member states are due to start discussing the proposal on Tuesday and the official hoped it would be approved this month.

BIG LOSSES

Travel restrictions because of COVID-19 have inflicted heavy losses on the tourism industry in the EU, which at times has struggled to agree a common response to the pandemic.

If the new proposals are agreed, specific EU countries would be expected – but not legally obliged – to follow the new joint approach. Greece has already agreed to welcome vaccinated tourists from Israel.

Other measures to support tourism this summer include a central EU register allowing free travel for the bloc’s citizens holding a so-called “green certificate” proving they have been vaccinated, have had a negative COVID-19 test or have immunity after recovering.

“The green certificate, for the Luxembourg government is one of the elements that would allow us to get back to normality as fast as possible,” Prime Minister Xavier Bettel said in separate comments on Monday.

The Commission recommended allowing people fully inoculated with EU-recognized vaccines to be able to enter from any country, and said other vaccines could be added if they are approved by the World Health Organization (WHO).

The European Medicines Agency has authorized the use of shots by Pfizer, Moderna, Johnson & Johnson and AstraZeneca in the EU.

The WHO has also approved those vaccines for use and is expected to decide on the use of two Chinese vaccines this week. Both agencies are considering Russia’s Sputnik V vaccine.

The Commission said reciprocity should be considered when deciding to allow leisure travel from third countries.

To limit the risk of importing new coronavirus variants, the Commission also proposed a new “emergency brake” that would allow the swift introduction of travel restrictions from countries where the health situation deteriorates sharply.

EU countries would review the situation every two weeks.

(Reporting by Gabriela Baczynska, Editing by John Chalmers, Timothy Heritage and Giles Elgood)

Vaccine protects COVID-19 survivors against variants; virus’ spike protein damages blood vessels

By Nancy Lapid

(Reuters) – The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

Vaccine protects COVID-19 survivors against variants

In COVID-19 survivors, the Pfizer/BioNTech mRNA vaccine protects not only against the original virus strain but also against worrisome variants, two studies show. UK researchers analyzed immune responses after a single dose of the vaccine in 51 people, including 25 people previously infected with an early version of the novel coronavirus. Survivors showed enhanced antibody responses against the newer, more infectious variants first seen in the UK and South Africa, whereas people who had not previously been infected did not produce antibodies that could neutralize the variants, according to a report on Friday in Science. Separately, U.S researchers studied 30 people after two doses of the vaccine. Immune responses were 3.4 times better at neutralizing the coronavirus in the 10 COVID-19 survivors than in the 20 who were not previously infected, they reported on medRxiv on Thursday ahead of peer review. The difference was even greater when looking at neutralization of new variants from the UK, South Africa and Brazil, said coauthor Fikadu Tafesse of Oregon Health & Science University. “For example, the South African variant, which is the best at evading neutralizing antibodies, was 6.5 times better blocked,” or neutralized, in blood samples from people who were vaccinated after infection, he said. “Our findings give people another reason to go out and get vaccinated even if they have already had COVID-19.”

COVID-19 spike protein damages blood vessels

The “spike” proteins that the coronavirus uses to help it break into cells inflicts other damage as well, according to a new study that shines a spotlight on the many ways COVID-19 attacks organs other than the lungs. The spike proteins themselves cause direct damage to the cells that line the blood vessels, scientists found in test tube experiments using an engineered version of the spike and artery-lining cells obtained from mice. After attaching itself to the ACE2 protein on healthy cells, the spike disrupts signaling from ACE2 to the mitochondria – the cell’s energy-generating structures – causing the mitochondria to become damaged, researchers reported on Friday in Circulation Research. COVID-19 is really a disease of the blood vessels, coauthor Uri Manor of the Salk Institute for Biological Studies in La Jolla, California said in a statement. The new findings could help explain the blood clots associated with COVID-19. They could also explain “why some people have strokes, and why some people have issues in other parts of the body,” Manor said. “The commonality between them is that they all have vascular underpinnings.”

Cancer screenings in U.S. plummeted during pandemic

Nearly 10 million screenings for three common cancers were missed in the U.S. because of the COVID-19 pandemic, a new study suggests. Researchers who compared monthly spring and summer screening rates in 2020 to rates in 2018 and 2019 found a 90.8% decline in breast cancer screening, a 79.3% decline in colorectal cancer screening and a 63.4% decline in prostate cancer screening just in the month of April 2020, researchers reported on Thursday in JAMA Oncology. “There was a deficit of 9.4 million in screening for the three major cancers across the United States that was most likely related to the COVID-19 pandemic,” said coauthor Dr. Ronald Chen of the University of Kansas Cancer Center in Kansas City. “This is a deficit we have to make up for in 2021.” One bit of good news from the study: telehealth visits seemed to be associated with getting cancer screenings back on track. Healthcare teams that could reach patients through telehealth “were able to come up with a plan for screening,” Chen said. “This emphasizes the importance of telehealth and the importance of continuing it after the pandemic is over.”

(Reporting by Nancy Lapid and Linda Carroll; Editing by Bill Berkrot)

Canada’s oil sands region becomes country’s COVID-19 hotspot

By Nia Williams

CALGARY, Alberta (Reuters) – Canada’s remote oil sands region in northern Alberta has become a COVID-19 hotspot, disrupting essential annual maintenance work at its massive oil sands plants.

The oil-rich province of Alberta is battling the highest rate of COVID-19 in Canada as the country grapples with a third wave of the pandemic, and on Thursday hit a record for new daily infections, topping 2,000 a day for the first time. The Regional Municipality of Wood Buffalo, home to the oil sands, has the highest rate of active cases per capita in the province.

Maintenance work is critical for production from Canada’s oil sands, which hold the world’s third-largest crude reserves and produce 3.1 million barrels per day, accounting for roughly three-quarters of the country’s total output.

Twelve oil sands plants including Canadian Natural Resources Ltd.’s Horizon and the Suncor Energy-owned Syncrude project are tackling outbreaks while in the middle of annual maintenance projects that require flying in extra workers from as far away as Atlantic Canada.

In total, there are 822 active cases at oil sands sites, according to Alberta Health. One worker has died.

Suncor has pushed back the maintenance turnaround on the U2 upgrader at its base plant site by at least a month to see if infections subside, said Terry Parker, executive director of the Building Trades of Alberta, representing 18 local unions.

“It’s a very stressful situation right now that they are facing,” Parker said, adding some workers were leaving the oil sands because of fears about becoming infected. “The owners are taking the precautions necessary, and we are still contracting this disease.”

A Suncor spokeswoman said the company is making minor adjustments to pre-work and day-to-day activities, but it remains on track with its planned maintenance.

CNRL, Suncor and Syncrude said COVID-19 safety protocols are in place. They have implemented rapid testing and isolation camps in a bid to slow the COVID-19 surge.

One contractor at CNRL’s Horizon plant, which has 328 active cases, the highest among the oil sands sites, said workers are tested every four days but that seemed to be having little impact on the outbreak.

“You have 8,000 people on site for four weeks, it’s going to be a thing,” he said, declining to be named because he is not authorized to speak to media.

Indigenous leaders this week called for stricter measures to control the spread of the virus and accused Alberta Premier Jason Kenney of “prioritizing profits over lives” by allowing infected workers to come to the region.

Gil McGowan, president of the Alberta Federation of Labor, called on Kenney to shut down work sites with outbreaks across the province, including the oil sands, to get the virus under control.

“This is a recipe for needless infection and needless deaths,” McGowan told Reuters.

Alberta has more than 21,000 active COVID-19 cases, including 632 people in hospital.

(Reporting by Nia Williams; Editing by Christopher Cushing)

Costa Rica to close non-essential businesses next week over COVID-19

SAN JOSE (Reuters) -Costa Rica will for the next week close non-essential businesses, including restaurants and bars, across the center of the country due to a sharp increase in new cases of COVID-19 and hospitalizations, the government said on Thursday.

From May 3-9, restaurants, bars, department stores, beauty salons, gyms and churches must close in 45 municipalities in central Costa Rica, where almost half the population lives and over two-thirds of new cases have been registered.

“We are in an unprecedented situation, and many people are going to die,” Health Minister Daniel Salas said after announcing 2,781 new daily infections, a record number. “There are already waiting lists to enter intensive care.”

The government is also imposing some restrictions on car travel inside the country, excepting car rentals.

Costa Rica, which remains open to international tourism, has so far reported almost 249,000 cases of COVID-19 and some 3,200 fatalities.

Some 10.5% of the population had been vaccinated as of Thursday, most of them over the age of 58, official data show.

(Reporting by Alvaro Murillo; Editing by Leslie Adler)

Exclusive: India’s oxygen crisis to ease by mid-May, output to jump 25% – executive

By Shivani Singh and Devjyot Ghoshal

NEW DELHI (Reuters) – India’s severe medical oxygen supply crisis is expected to ease by mid-May, a top industry executive told Reuters, with output rising by 25% and transport infrastructure ready to cope with a surge in demand caused by a dramatic rise in coronavirus cases.

Dozens of hospitals in cities such as New Delhi and Mumbai have run short of the gas this month, sending relatives of patients scrambling for oxygen cylinders, sometimes in vain.

Medical oxygen consumption in India has shot up more than eight-fold from usual levels to about 7,200 tonnes per day this month, said Moloy Banerjee of Linde Plc, the country’s biggest producer.

“This is what is causing the crisis because no one was prepared for it, particularly the steep curve up,” Banerjee, who heads the company’s South Asia gas business, told Reuters on Thursday.

Linde – whose two affiliates in the country are Linde India and Praxair India – and other suppliers are ramping up production to a total of more than 9,000 tonnes per day by the middle of next month, he said.

A logistics crisis impeding the speedy movement of oxygen from surplus regions in eastern India to hard-hit northern and western areas would also be resolved in the coming weeks as more distribution assets are deployed, Banerjee said.

“My expectation is that by the middle of May we will definitely have the transport infrastructure in place that allows us to service this demand across the country,” he said.

Banerjee said India was importing around 100 cryogenic containers to transport large quantities of liquid medical oxygen, with Linde providing 60 of those. Some are being flown in by Indian Air Force aircraft.

Many of these containers will be placed on dedicated trains that would cut across the country, each carrying between 80-160 tonnes of liquid oxygen and delivering to multiple cities.

The company is also looking to double the number of oxygen cylinders in its distribution network to at least 10,000, which would improve supply to rural areas with weak infrastructure.

“We are trying to create a hub-and-spoke type of system so that we make a lot of liquid oxygen available at the local area, from where the local dealers can pick it up,” Banerjee said.

India’s total COVID-19 cases passed 18 million on Thursday after another world record number of daily infections.

(Reporting by Shivani Singh and Devjyot Ghoshal; Editing by Krishna N. Das and Giles Elgood)

France’s Macron charts way out of third COVID-19 lockdown

By Elizabeth Pineau

PARIS (Reuters) -France will start relaxing a nightly curfew and allow cafes, bars and restaurants to offer outside service from May 19, as President Emmanuel Macron charts a way out of a third COVID-19 lockdown.

Macron, who is under pressure from business groups and a COVID-weary public to open up the economy again, announced in an interview with the regional papers a four-phase plan for unwinding France’s month-long stay-at-home order.

The easing will come despite the numbers of new daily cases and COVID-19 patients being treated in intensive care being far higher than when the two previous lockdowns were rolled back. Macron said the vaccine rollout made this possible.

“I have never gambled on the health and safety of our citizens,” Macron said. “I take responsibility for the choices I make, but these are never bets.”

The plan envisages the nightly curfew being pushed back to 2100 from 1900 CET from May 19 and to 2300 from June 9, before being scrapped completely on June 30.

Museums, cinemas and theatres will also be allowed to reopen on May 19. Foreign tourists with a “health pass” will be allowed to visit France again from June 9, according to the timetable published by Ouest France and other newspapers.

The timetable is provisional and could be delayed on a region-by-region basis in areas where intensive care units are close to saturation or the COVID-19 incidence rate exceeds 400 cases per 100,000 inhabitants.

‘EMERGENCY BRAKE’

“We will be able to pull an emergency brake in territories where the virus is too present,” Macron said.

The incidence rate in Paris and its surrounds was an average 459 per 100,000 people in the seven days up to April 25 and is falling, data showed. Ile de France is home to nearly a fifth of France’s population and accounts for 30% of economic activity.

About 22% of all French citizens have received at least one dose of a COVID-19 vaccine, according to a Reuters tracker.

Accelerating the rollout in France, Europe and in developing countries is paramount to push back against the virus, Macron said.

Opening up the vaccine to more people in France, Macron said COVID shots would be made available to all obese adults from May 1.

Macron said France could use a digital or paper-based ‘health pass’ to help curb the spread of the virus at events with large crowds such as sport stadia or festivals. But he said it would not be right to use them at everyday venues like restaurants or cinemas.

“A health pass will never be a right of access that differentiates the French,” the president said. “As it pertains to public liberties, parliament will debate the matter.”

France’s main COVID-19 indicators all showed some signs of improvement on Wednesday, with the seven-day moving average of daily new infections falling to 27,366 compared with 38,000 when the lockdown began.

France has recorded 5.57 million COVID-19 cases and 103,947 deaths since the start of the pandemic.

(Reporting by Elizabeth Pineau; writing by Richard Lough; Editing by Gareth Jones and Sonya Hepinstall)

Vaccinated Hong Kong residents ready to party till 2 a.m. curfew as bars reopen

By Farah Master and Aleksander Solum

HONG KONG (Reuters) -In Hong Kong’s famed party zone Lan Kwai Fong, dormant bars and clubs opened to serve customers again, but only for those who have had at least one vaccine shot – one of the few examples globally of offering greater freedom for the vaccinated. Bar staff need to have gotten at least one coronavirus vaccine dose too, and patrons must register with a government mobile tracking application as they enter.

“Before it was a dead city, now it has loosened a little and everyone is happier,” said Vanessa, a 25-year-old office worker who was visiting the popular bar district. The Chinese special administrative region has kept COVID-19 transmission largely under control. Hong Kong has recorded more than 11,700 coronavirus cases, far lower than other developed cities. The new rules come as authorities there try to encourage the city’s 7.5 million residents to get vaccinated; only about 12% have received their first dose. “The re-opening of bars and the extension of opening hours are incentives for people to receive the vaccination, while the most important thing … is to prevent the spread of the infection, should it hit us again,” said Professor Lau Chak Sing, head of department of Medicine at the University of Hong Kong (HKU). “In an ideal situation, one should complete the course of vaccination to ensure protection,” he said, adding that with Hong Kong’s adequate supply of vaccines, people eager to go to bars would complete both their first and second doses. Venues including nightclubs, karaoke lounges and bathhouses, can stay open until 2 a.m. from Thursday but must operate at half capacity, Sophia Chan, the city’s Health Secretary said. Bars can only seat two people per table.

COMPLEX RULES

Customers must scan the government’s app and show their vaccination record – stored electronically on their mobile phones – when they enter. Many residents have declined to use the app because of privacy concerns, choosing instead to write down their details. Restaurants can stay open until 2 a.m. and seat up to 8 people at a table, provided they have received both vaccine doses. But they must have a separate area for unvaccinated customers, and depending on whether staff have been vaccinated, might be required to close at 10 p.m. or midnight. The multi-tiered rules are tough to implement immediately, industry executives said, and many venues cannot open fully as they cannot force staff to get vaccinated. Allan Zeman, chairman of Lan Kwai Fong Group, a property owner and developer in the nightclub district, said that bar owners were desperate to reopen but that there remained a lot of apprehension among staff about vaccinations. “The restrictions will not be easy. Customers themselves need to have one vaccine, that in itself is very limiting,” he said, adding that the measures were a baby step forward and an experiment for both the government and the industry.

Ben Leung, president of Hong Kong’s Licensed Bar and Club Association, said only around 50% of the city’s 1280 bars would open on Thursday with others remaining closed until all their workers had received vaccinations.

Simon Wong, chief executive of LH Group, which operates dozens of restaurants and employs hundreds of staff, wrote on his Facebook page that the new arrangement was “so complicated”. Wong said his restaurants would only be able to seat 4 people per table and stay open until 10 p.m., as many staff did not want to get vaccinated. Hong Kong residents have been hesitant since the vaccination program began in February because of a lack of confidence in China’s Sinovac vaccine and fears of adverse reactions. Some residents have shown greater take-up for the vaccine offered by Germany’s BioNTech in the city but overall figures remain far below satisfactory, said the city’s leader, Carrie Lam.

(Additional reporting by Donny Kwok and Joyce Zhou ; Writing by Farah Master. Editing by Gerry Doyle and Toby Chopra)

German officials hope COVID-19 third wave has crested

By Emma Thomasson and Caroline Copley

BERLIN (Reuters) -A third wave of the coronavirus pandemic seems to have peaked in Germany and a record number of vaccinations should help turn the tide, although it is too soon to sound the all-clear as hospitals remain overloaded, health officials said on Thursday.

“The figures must not only stagnate, they must go down,” Health Minister Jens Spahn told a news conference, adding that a sustainable fall was a prerequisite for the lockdown to ease.

“Two to three days is not a trend. It is a good signal but what is decisive is to make a trend out of it,” he said, adding nearly 1.1 million people were vaccinated on Wednesday, more than 1% of the population and more than on any other day so far.

Germany’s seven-day average of coronavirus cases per 100,000 people fell on Thursday for the third day in a row to 155 – its lowest level in two weeks, data from the Robert Koch Institute (RKI) for infectious diseases showed.

The incidence figure – a key metric used by the German government to determine when to tighten or ease lockdowns – hit 169 on Monday, but has fallen each day since then. The last time it was under 160 was on April 14, when the incidence was 153.

RKI President Lothar Wieler cautioned that the pandemic would not be over until it was under control around the world, noting that global cases had risen 24% in the last week.

LOCKDOWNS

New legislation enables the federal government to impose curfews from 10 p.m. to 5 a.m. in areas where cases exceed 100 per 100,000 residents on three consecutive days. The rules also include stricter limits on private gatherings and shopping.

Schools will have to close and return to online lessons if cases reach 165 per 100,000 residents on three consecutive days.

If the European Union’s watchdog approves COVID-19 vaccines for children, Germany will be able to vaccinate under 12-year-olds during the summer holidays at the latest, Spahn said.

The number of new confirmed coronavirus cases rose by 24,736 on Thursday – almost 5,000 fewer than those recorded a week ago – bringing Germany’s total caseload since the start of the pandemic to 3,357,268.

The total COVID-19 death toll rose by 264 to 82,544.

(Reporting by Emma Thomasson, Caroline Copley, editing by Kirsti Knolle and Gareth Jones)