Congolese cross-border trader’s Ebola death fuels Uganda outbreak fears

FILE PHOTO: A Congolese health worker prepares to administer Ebola vaccine, outside the house of a victim who died from Ebola in the village of Mangina in North Kivu province of the Democratic Republic of Congo, August 18, 2018. REUTERS/Olivia Acland/File Photo

By Tom Miles

GENEVA (Reuters) – A Congolese woman who died of Ebola this month vomited four times in a Ugandan market after crossing the border days earlier to sell fish, the WHO said, fuelling fears that the virus may be spreading beyond the Democratic Republic of Congo.

The current outbreak of the highly infectious disease has been all but confined to Congo, killing 1,673 people there – more than two-thirds of those who contracted it – over the past year, and three in Uganda last month.

A World Health Organization panel is debating whether to declare the outbreak “of international concern”, a designation that the agency’s head suggested a case this month in the large Congolese city of Goma had made more likely.

The fisherwoman traveled across the border to Mpondwe market on July 11, according to a Ugandan Health Ministry report published on Wednesday by the WHO.

It said 19 fishmongers were listed as having had possible contact with her while another 590 could be targeted for vaccination.

The health response to the virus relies on tracking down and testing people who may have been exposed to it and vaccinating them and anybody they have had contact with.

Ugandan and Congolese officials were working to find people who might have been put at risk by the dead woman, who appeared to have used an illegal border crossing, health ministry spokesman Emmanuel Ainebyona said.

So far “no one has been found to be positive of the Ebola virus. The team is still monitoring the tested traders,” he said.

The report said health workers had not established where the fishmonger spent nights, who transported her merchandise and who cleaned up her vomit.

The Ministry and the WHO said there were currently no confirmed Ebola cases in Uganda.

The WHO’s emergency committee of international experts were meeting on Wednesday for a fourth time to consider if the 11-month outbreak constituted a “public health emergency of international concern” (PHEIC), and will announce their decision at 1700 GMT.

A PHEIC declaration would be just the fifth in WHO history and include recommendations for international action. It could also help unlock sorely needed funds.

Last month the committee decided the potential disruption of declaring one risked causing economic harm while achieving nothing.

But WHO chief Tedros Adhanom Ghebreyesus said this week that the case in Goma was a potential game-changer since it meant Ebola might now spread among the urban population and into neighboring Rwanda.

A separate WHO report cited a very high risk for Uganda’s Arua district, which borders a Congolese area where an Ebola patient died after having had contact with over 200 people. Two deaths in Arua were under investigation.

(Reporting by Tom Miles and Nairobi newsroom; Editing by Gareth Jones and John Stonestreet)

First Ebola patient in eastern Congo’s main city dies, fears of epidemic spreading

A health worker checks the temperature of a woman as she crosses the Mpondwe border point separating Uganda and the Democratic Republic of Congo as part of the ebola screening at the computerised Mpondwe Health Screening Facility in Mpondwe, Uganda June 13, 2019. REUTERS/Newton Nabwaya

GOMA, Democratic Republic of Congo (Reuters) – The first Ebola patient in eastern Democratic Republic of Congo’s largest city, Goma, has died, the government said on Tuesday.

The spread of the virus to Goma, a city of roughly 1 million people on the border with Rwanda, has raised fears the outbreak, which is already the second deadliest Ebola epidemic ever, could spread more widely.

The patient was a priest who became infected during a visit to the town of Butembo, one of the epicenters of the outbreak, before taking a bus to Goma, according to Congo’s health ministry.

He was being driven from Goma to a clinic in Butembo on Monday to receive treatment when he died, North Kivu province’s Governor Carly Nzanzu told an Ebola response meeting.

The World Health Organization (WHO) said on Monday that health officials had identified 60 people who had come into contact with the pastor since he was taken ill and that half of them had been vaccinated.

Goma, a lakeside city more than 350 kilometers (220 miles) south of where Ebola was first detected a year ago, is the largest city to be affected by the outbreak, which has infected more than 2,500 people and killed nearly 1,700.

Three Ebola cases which originated in Congo were confirmed in neighboring Uganda a month ago, but no new cases have since been registered in that country.

(Reporting by Stanis Bujakera and Djaffar Al Katanty, Writing by Anna Pujol-Mazzini, Editing by Ed Osmond)

U.S. recorded 18 new cases of measles last week

FILE PHOTO: Materials are seen left at demonstration by people opposed to childhood vaccination after officials in Rockland County, a New York City suburb, banned children not vaccinated against measles from public spaces, in West Nyack, New York, U.S. March 28, 2019. REUTERS/Mike Segar/File Photo

(Reuters) – The United States recorded 18 new measles cases last week, taking the total for the year to 1,095 in the worst outbreak since 1992, federal health officials said on Monday.

The U.S. Centers for Disease Control and Prevention said it has recorded cases of the highly contagious and sometimes deadly disease in 28 states as of June 27, the majority of them in New York City and nearby Rockland County.

The running tally includes both active cases and those that have since resolved. No fatalities have been reported.

Health experts say the virus has spread among school-age children whose parents declined to give them the measles-mumps-rubella vaccine, which confers immunity to the disease. A vocal fringe of U.S. parents cite concerns that the vaccine may cause autism, despite scientific studies that have debunked such claims.

Measles was declared eliminated in the United States in 2000, meaning there was no continuous transmission of the disease for a year. Still, cases of the virus occur and spread via travelers coming from countries where measles is common.

CDC officials have warned that the country risks losing its measles elimination status if the ongoing outbreak, which began in October 2018 in New York, continues until October 2019.

(Reporting by Manas Mishra in Bengaluru; Editing by Arun Koyyur and Bill Berkrot)

U.S. records 33 new measles cases, raising year’s total to 1,077

FILE PHOTO: A vial of the measles, mumps, and rubella (MMR) vaccine at the International Community Health Services clinic in Seattle, Washington, U.S., March 20, 2019. REUTERS/Lindsey Wasson

(Reuters) – The United States recorded 33 new measles cases last week, bringing the number of confirmed cases this year to 1,077 in the worst outbreak of the virus since 1992, federal health officials said on Monday.

The U.S. Centers for Disease Control and Prevention said the cases of the highly contagious and sometimes deadly disease rose 3% in the week ended June 20 from the prior week. The 2019 outbreak, which has spread to 28 states, is the worst since 1992, when 2,126 cases were recorded.

Health experts say the virus has spread among school-age children whose parents declined to give them the measles-mumps-rubella vaccine, which confers immunity to the disease. A vocal fringe of U.S. parents, some in New York’s ultra-Orthodox Jewish communities, cite concerns that the vaccine may cause autism, despite scientific studies that have debunked such claims.

The disease has mostly affected children who have not received the vaccine.

Measles was declared eliminated in the United States in 2000, meaning there was no continuous transmission of the disease for a year. Still, cases of the virus occur and spread via travelers coming from countries where measles is common.

CDC officials have warned that the country risks losing its measles elimination status if the ongoing outbreak, which began in October 2018 in New York, continues until October 2019.

The outbreak has escalated since 82 people in 2018 and more than 40 people in 2019 brought measles to the United States from other countries, most frequently Ukraine, Israel and the Philippines, federal officials said.

(Reporting by Gabriella Borter in New York and Ankur Banerjee in Bengaluru; Editing by Shailesh Kuber and Susan Thomas)

U.S. measles outbreak spreads to Idaho and Virginia, hits 1,022 cases

FILE PHOTO: A vial of the measles, mumps, and rubella (MMR) vaccine at the International Community Health Services clinic in Seattle, Washington, U.S., March 20, 2019. REUTERS/Lindsey Wasson/File Photo

The United States’ worst measles outbreak in a quarter-century spread to Idaho and Virginia last week as public health authorities on Monday reported 41 new cases of the highly contagious and sometimes deadly disease.

The U.S. has recorded 1,022 cases of the diseases this year as of June 6, in an outbreak blamed on misinformation about vaccines, the U.S. Centers for Disease Control and Prevention said.

The 2019 outbreak, which has reached 28 states, is the worst since 1992, when 2,126 cases were recorded.

Federal health officials attribute this year’s outbreak to U.S. parents who refuse to vaccinate their children. These parents believe, contrary to scientific evidence, that ingredients in the vaccine can cause autism.

“We cannot say this enough: Vaccines are a safe and highly effective public health tool that can prevent this disease and end the current outbreak,” Health and Human Services Secretary Alex Azar said in a statement last week.

Measles was declared eliminated in the United States in 2000, meaning there was no continuous transmission of the disease for a year. Still, cases of the virus occur and spread via travelers coming from countries where measles is common.

CDC officials have warned that the country risks losing its measles elimination status if the ongoing outbreak, which began in October 2018 in New York, continues until October 2019.

(Reporting by Gabriella Borter in New York and Aakash Jagadeesh Babu in Bengaluru; Editing by Scott Malone and Susan Thomas)

U.S. measles outbreak grows with 60 new measles cases across 26 states

FILE PHOTO: Centers for Disease Control and Prevention (CDC) headquarters in Atlanta, Georgia September 30, 2014. REUTERS/Tami Chappell/File Photo/File Photo

(Reuters) – The United States recorded 60 new measles cases last week, taking confirmed cases for the year to 940, the worst outbreak since 1994 and since measles was declared eliminated in 2000, federal health officials said on Monday.

The U.S. Centers for Disease Control and Prevention reported a 6.8% increase in the number of measles cases in the week ended May 24 in an outbreak that has now reached 26 states. The agency has been providing weekly updates every Monday.

Experts warn that the outbreak is not over as the number of cases edges closer to the 1994 total of 958. That was the highest number since 1992, when the CDC recorded 2,126 cases.

Public health officials have blamed the measles resurgence on the spread of misinformation about vaccines, as a vocal fringe of parents oppose vaccines, believing, contrary to scientific studies, that ingredients in them can cause autism.

Although the virus was eliminated from the United States in 2000, meaning the disease was no longer a constant presence, outbreaks still happen via travelers coming from countries where measles is still common, according to the U.S. Centers for Disease Control and Prevention.

(Reporting by Shubham Kalia and Saumya Sibi Joseph in Bengaluru; Editing by Phil Berlowitz)

WHO issues warning as measles infects 34,000 in Europe this year

FILE PHOTO: A vial of the measles, mumps, and rubella (MMR) vaccine is pictured at the International Community Health Services clinic in Seattle, Washington, U.S., March 20, 2019. REUTERS/Lindsey Wasson/File Photo

By Kate Kelland

LONDON (Reuters) – More than 34,000 people across Europe caught measles in the first two months of 2019, with the vast majority of cases in Ukraine, the World Health Organization said on Tuesday as it urged authorities to ensure vulnerable people get vaccinated.

The death toll among 34,300 cases reported across 42 countries in the WHO’s European region reached 13, with the virus killing people in Ukraine – which is suffering a measles epidemic – as well as in Romania and Albania. The risk is that outbreaks may continue to spread, the WHO warned.

“If outbreak response is not timely and comprehensive, the virus will find its way into more pockets of vulnerable individuals and potentially spread to additional countries within and beyond the region,” it said in a statement.

“Every opportunity should be used to vaccinate susceptible children, adolescents and adults.”

Measles is a highly contagious disease that can kill and cause blindness, deafness or brain damage. It can be prevented with two doses of an effective vaccine, but – in part due to pockets of unvaccinated people – it is currently spreading in outbreaks in many parts of the world including in the United States, the Philippines and Thailand.

In Europe, the majority of measles cases so far in 2019 are in Ukraine, which saw more than 25,000 people infected in the first two months of the year.

There is no specific antiviral treatment for measles, and vaccination is the only way to prevent it, the WHO said. Most cases are in unvaccinated or under-vaccinated people.

It added that even though the region had its highest ever estimated coverage for the second dose of measles vaccination in 2017 – at around 90 percent – some countries have had problems, including declining or stagnating immunization coverage in some cases, low coverage in some marginalized groups, and immunity gaps in older populations.

The WHO called on national health authorities across the region to focus efforts on ensuring all population groups have access to vaccines.

“The impact on public health will persist until the ongoing outbreaks are controlled,” it said, adding that health authorities should “identify who has been missed in the past and reach them with the vaccines they need.”

A report by the United Nations children’s fund UNICEF last month found that more than 20 million children a year missed out on measles vaccines across the world in the past eight years, laying the ground for dangerous outbreaks.

(Reporting by Kate Kelland; Editing by Mark Heinrich)

U.S. measles outbreak raises questions about immunity in adults

FILE PHOTO: An illustration provides a 3D graphical representation of a spherical-shaped, measles virus particle studded with glycoprotein tubercles in this handout image obtained by Reuters April 9, 2019. Centers for Disease Control and Prevention (CDC)/Handout via REUTERS/File Photo

By Julie Steenhuysen

(Reuters) – Adults in the United States who were vaccinated against measles decades ago may need a new dose depending on when they received the shot and their exposure risk, according to public health experts battling the nation’s largest outbreak since the virus was deemed eliminated in 2000.

Up to 10 percent of the 695 confirmed measles cases in the current outbreak occurred in people who received one or two doses of the vaccine, according to the U.S. Centers for Disease Control and Prevention.

The figure illustrates what can happen when a large number of individuals, even those who have been vaccinated, are exposed to the measles. CDC recommends that people who are living in or traveling to outbreak areas should check their vaccination status and consider getting a new dose.

Dr. Allison Bartlett, an infectious disease expert at the University of Chicago Medicine, said the “continued vulnerability to infection” is why high-risk adults such as healthcare workers are routinely advised to get a second dose of the measles vaccine if they have not had one.

But knowing your vaccination status can be tricky, experts said.

“It’s complicated and often futile because it’s very difficult to resurrect those old records,” said Dr. William Schaffner, an infectious disease expert at Vanderbilt University Medical Center.

People vaccinated in the United States since 1989 would most likely have received two doses of the combined measles, mumps and rubella (MMR) shot under federal guidelines, and that is still considered the standard for protection.

Anyone vaccinated between 1963 and 1989 would likely have received only one dose, with many people immunized in the earlier years receiving an inactivated version of the virus. Americans born before 1957 are considered immune as they would have been exposed to the virus directly in an outbreak.

Merck & Co Inc is the sole U.S. provider of the MMR vaccine. The company said in a statement that it has “taken steps to increase U.S. supply” of the vaccine due to the current outbreak.

HIGHLY CONTAGIOUS

The measles virus is highly contagious and can cause blindness, deafness, brain damage or death. It is currently spreading in outbreaks in many parts of the world.

According to the World Health Organization, 95 percent of a population needs to be vaccinated to provide “herd immunity,” a form of indirect protection that prevents infection in people too young or sick to be vaccinated. U.S. public health officials have blamed the current outbreak in part on rising rates of vaccine skepticism that have reduced measles immunity in certain communities.

For travelers to outbreak areas abroad, the CDC recommends adults consider getting another dose of MMR unless they have proof of receiving two prior doses, take a blood test showing immunity, or were born before 1957.

In general, the CDC says two doses of the measles vaccine should provide 97 percent protection; one dose should offer 93 percent protection. However, immunity can wane over time.

This has occurred even in adults with two documented doses of the vaccine, said Dr. Michael Phillips, chief epidemiologist at NYU Langone Health, which serves parts of New York City, a hot spot in the U.S. outbreak.

He said in kids, “the vaccine is really effective,” but in some adults, memory T-cells, which recognize and attack germs, do not fight the virus as effectively as they once did.

Rapid blood tests are available that can detect whether a person is immune based on the level of measles antibodies, but the tests are not 100 percent reliable.

Adults who have any doubt about their immunity should get another dose, Schaffner said: “It’s safe. There’s no downside risk. Just roll up your sleeve.”

(Reporting by Julie Steenhuysen in Chicago; Additional reporting by Mike Erman and Gabriella Borter in New York; Editing by Lisa Shumaker)

New York City defends measles vaccination order in court

FILE PHOTO: A sign warning people of measles in the ultra-Orthodox Jewish community of Williamsburg, two days after New York City Mayor Bill de Blasio declared a public health emergency in parts of Brooklyn in response to a measles outbreak, is seen in New York, U.S., April 11, 2019. REUTERS/Shannon Stapleton/File Photo

By Jonathan Allen

NEW YORK (Reuters) – New York City’s Department of Health defended its mandatory measles vaccination order in a state court on Thursday after a group of anonymous Brooklyn parents sued, arguing that the order was unconstitutional.

The department issued the order last week, saying it was an unusual but necessary step to contain the worst outbreak of the highly contagious virus seen in the city since 1991. The outbreak has infected 329 people so far, most of them children from Orthodox Jewish communities in Brooklyn.

The order, which was extended this week, requires unvaccinated people living in certain affected Brooklyn neighborhoods to get the measles-mumps-rubella vaccine if they cannot otherwise demonstrate immunity to measles, or face a $1,000 fine.

Five people who said they were parents living in the affected neighborhoods sued the department this week in Brooklyn’s Supreme Court, filing their lawsuit anonymously in order, their lawyers said, to protect their children’s privacy.

Their lawyers told Judge Lawrence Knipel that the city had overstepped its authority, saying 329 confirmed cases so far did not constitute an epidemic. They argued that quarantining people with measles would be a preferable approach.

“It’s excessive, it’s coercive,” Robert Krakow, a lawyer for the parents, said in court. He said he estimated that 0.0006 percent of the population of Brooklyn and Queens had measles. “That’s not an epidemic,” he said. “It’s not Ebola. It’s not smallpox.” He said even vaccinated people could spread the virus and that the vaccination carried a “risk of injury,” which the city disputed.

The department’s lawyers argued that this is a serious outbreak and that quarantining was ineffective because infected people can be contagious before symptoms appear. They said the lawsuit relied on bogus or discredited science.

Lawyers for the Health Department said three or more cases constituted an outbreak, given the United States had declared the disease eliminated in 2000, meaning it is no longer present year round. Measles can lead to serious complications and death.

“The percentage is irrelevant,” Sherrill Kurland, a lawyer from the city’s Law Department, told the court. “The rates of transmission has continued to increase. These areas remain serious for concern.”

The Brooklyn outbreak has been traced to an unvaccinated child who became infected on a visit to Israel, which is also grappling with an outbreak.

The number of measles cases worldwide nearly quadrupled in the first quarter of 2019 to 112,163 compared with the same period last year, the World Health Organization said this week, while the U.S. Centers for Disease Control and Prevention has reported measles cases in at least 20 U.S. states.

Judge Knipel said he would release his decision on whether to temporarily block the city’s order by the end of the week.

(Reporting by Jonathan Allen; Editing by Bill Berkrot)

CDC investigates E.coli outbreak in several states

FILE PHOTO: A general view of the Centers for Disease Control and Prevention (CDC) headquarters in Atlanta, Georgia September 30, 2014. REUTERS/Tami Chappell/File Photo

(Reuters) – The Centers for Disease Control and Prevention (CDC) and several other U.S. agencies are investigating an E.coli outbreak in five states, the CDC said on Friday.

The CDC, the U.S. Department of Agriculture’s Food Safety and Inspection Service, the U.S. Food and Drug Administration and several states are investigating the outbreak of toxin-producing E.coli O103 infections.

Escherichia coli, or E.coli bacteria, normally lives in the intestines of healthy people and animals. Although many strains of the bacteria are harmless, certain strains can cause severe abdominal cramps, bloody diarrhea and vomiting.

Georgia, Kentucky, Ohio, Tennessee and Virginia are the five states that have reported E.coli infections relating to particular strain of the bacteria.

As many as 72 people from these states have reported infections and eight have been hospitalized as of April 4, 2019, the agency said. No deaths were reported.

The investigation is still going on and the reason for the outbreak is yet to be identified, the agency said.

(Reporting by Aakash Jagadeesh Babu in Bengaluru; Editing by James Emmanuel)