Just days after declaring Marburg virus outbreak Rwanda reports 8 people have already died

Marburg-disease

Important Takeaways:

  • Rwanda, a landlocked country in central Africa, declared an outbreak on Friday and a day later the first six deaths were reported.
  • Rwanda says eight people have died so far from the Ebola-like and highly contagious Marburg virus, the deadly hemorrhagic fever that has no authorized vaccine or treatment.
  • The public has been urged to avoid physical contact to help curb the spread. Some 300 people who came into contact with those confirmed to have the virus have also been identified, and an unspecified number of them have been put in isolation facilities.
  • Most of the affected are healthcare workers across six out of 30 districts in the country.
  • “Marburg is a rare disease,” Nsanzimana told journalists. “We are intensifying contact tracing and testing to help stop the spread.”
  • A person infected with the virus can take between three days and three weeks to show symptoms, he added.
  • Separately, Rwanda has so far reported six cases of mpox, a disease caused by a virus related to smallpox but that typically causes milder symptoms.

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As Americans navigate conflicting COVID-19 mask advice, ‘everyone is confused’

By Joseph Ax and Tim Reid

PRINCETON, N.J./SANTA MONICA, Calif. (Reuters) – A COVID-19 surge ignited in parts of the United States by the highly contagious Delta variant and vaccine hesitancy has led to new mask mandates and deep confusion among some people about which guidance to follow.

In Los Angeles County, leaders have reinstated an indoor mask mandate, even for the fully vaccinated. Officials in Houston and New Orleans also raised coronavirus alert levels this week and told people to mask up.

In Florida, however, Governor Ron DeSantis said on Thursday children will not be required to wear masks in school there this fall, arguing that “we need our kids to breathe.” Hours later, White House press secretary Jen Psaki told reporters: “If I were a parent in Florida, that would be greatly concerning to me.”

“Everyone is confused about what they should be doing,” said Daniel Blacksheare, a 20-year-old in Santa Monica, California, who said he was infected twice last year. “I don’t understand why we have to suddenly wear a mask again.”

The county sheriff in Los Angeles County said his department will not enforce the measure.

The conflicting advice from officials at city, county, state and federal levels of government comes as hospital officials in the harder-hit states with lower vaccination rates are sounding the alarm about their systems being overwhelmed.

The seven-day average of new COVID-19 cases in the United States is up 53% over the previous week, according to the Centers for Disease Control and Prevention on Thursday. The Delta variant makes up more than 80% of the new cases across the country.

Much of the guidance falls along the same political lines as earlier in the pandemic. Leaders in heavily Republican states generally eschew masks, and Democrats insist upon them.

Schools are a particular tension point nationwide. Children under age 12 are still not eligible for coronavirus vaccines, and many parents consider masks as the best remaining defense.

Yet as some areas return to the classroom in just a few weeks, there are wide divisions over whether children should be wearing masks in schools.

The American Academy of Pediatrics this week released updated recommendations for schools that included mask wearing for everyone over the age of 2, regardless of vaccination status. President Joe Biden said on Wednesday that unvaccinated children should wear masks in schools.

But the CDC on Thursday said it is not changing its mask guidance for schools, including that masks are only required for those over age 2 who have not been vaccinated. The CDC in May relaxed its guidance so that fully vaccinated people do not need to wear masks in most public spaces.

In Princeton, New Jersey, Ximena Skovron said she finds the dust-ups over masks and what the guidance actually is to be perplexing.

“I’m vaccinated, and the rules seem to change,” she said. “But it’s also inconsistent. You’ve got two grocery stores in town: one requires masks, one doesn’t.”

Skovron said she does not think states should reimpose mask mandates.

“Vaccines are readily available. The ability to protect yourself is there,” she said. “If you refuse, you should assume the risk instead of imposing on the rest of society.”

Her 6-year-old daughter will enter first grade this fall, and Skovron said she hopes the school does not require masks, citing the extremely low rate of serious COVID-19 incidence among small children.

“It just seems like such overkill for children to wear masks,” she said.

But Melissa Riccobono, 44, of Lawrenceville, New Jersey, said she is pro-mask and thinks there should be mandates when and where necessary.

“If you’re choosing not to vaccinate, that’s your choice, and I’m fine with that – but it’s not your choice whether to wear a mask,” she said.

(Reporting by Tim Reid in Santa Monica, California, and Joseph Ax in Princeton, New Jersey; Additional reporting by Brad Brooks in Lubbock, Texas, and Carl O’Donnell in Washington; Editing by Colleen Jenkins and Grant McCool)

Delta variant already dominant in U.S., CDC estimates show

By Mrinalika Roy

(Reuters) – The Delta variant is already the dominant strain of COVID-19 in the United States, according to data modeling done by the U.S. Centers for Disease Control and Prevention (CDC).

According to the health agency’s estimates the Delta variant became dominant in the country over the two weeks ended July 3, with 51.7% cases linked to the variant that was first identified in India.

The proportion of cases linked to the Alpha variant which was first identified in Britain and had been dominant in the United States so far, fell to 28.7%.

The data, which shows the estimated biweekly proportions of the most common SARS-CoV-2 lineages circulating in the United States, is based on sequences collected through CDC’s national genomic surveillance since Dec. 20, 2020.

The Delta variant, which is becoming dominant in many countries, is more easily transmitted than earlier versions of the coronavirus and may cause more severe disease, especially among younger people. It has now been found in every U.S. state, health officials have said.

On Tuesday, U.S. President Joe Biden encouraged Americans who have not yet been vaccinated against COVID-19 to get their shots to protect themselves from the widely spreading, highly contagious variant.

So far, preliminary data has shown that vaccines made by Pfizer Inc and BioNTech, AstraZeneca and Moderna are largely protective against Delta, with the concentration of virus-neutralizing antibodies being somewhat reduced.

(Reporting by Mrinalika Roy in Bengaluru; Editing by Sandra Maler)

White House sending special teams to COVID-19 hot spots to combat Delta variant

By Andrea Shalal and Carl O’Donnell

WASHINGTON (Reuters) – The White House on Thursday said it would send out special teams to hot spots around the United States to combat the highly contagious Delta coronavirus variant, and urgently called on Americans who have not been vaccinated to get shots.

White House COVID-19 senior adviser Jeffrey Zients told reporters the “surge response” teams would be ready to speed additional testing supplies and therapeutics to communities that were experiencing increases in COVID-19 cases.

The seven-day-average number of COVID-19 cases in the United States has risen 10% since last week, U.S. Centers for Disease Control and Prevention Director (CDC) Rochelle Walensky said on a Tuesday press call.

The more easily transmitted Delta variant, which was first detected in India, is thought to have become the second most prevalent coronavirus variant in the United States, she added.

“It is clear that communities where people remain unvaccinated are communities that remain vulnerable,” Walensky said, adding that 1,000 counties in the United States have vaccination rates below 30%.

Zients said federal personnel will assist communities with public health staffing and the CDC will provide assistance in containing potential outbreaks.

The United States remains a world leader in COVID-19 vaccinations, with more than 180 million Americans having received at least one shot.

(Reporting by Lisa Lambert, Carl O’Donnell and Andrea Shalal; Editing by Jonathan Oatis and Bill Berkrot)

Delta variant gains ground in U.S., men do worse with COVID-19

By Nancy Lapid

(Reuters) – The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

Highly contagious Delta variant gaining ground in U.S.

The highly transmissible Delta variant of SARS-CoV-2, first identified in India, has become the most prevalent variant among new COVID-19 cases in the United States, according to California-based genomics company Helix. The company’s computer models indicate that Delta now accounts for around 40% of new U.S. cases, Dr. William Lee, vice president of science at Helix, said in a statement provided to Reuters. The models, based on 27,717 virus samples from 687 counties across the United States, also indicated that the worrisome Gamma variant, first identified in Brazil, accounts for about 15% of new cases. Helix researchers have noted occasional cases of an “offspring” variant of Delta called Delta-plus, but they “aren’t seeing any evidence suggesting that these are driving the growth of Delta around the country yet,” Lee said. Earlier in June, the researchers reported on the medical website medRxiv ahead of peer review that the percentage of new COVID-19 cases due to the variant first identified in Britain, known as Alpha, had dropped from 70% in mid-April 2021 to 42% six weeks later. Now, Lee said, Alpha “is down to around 20%.” Lee said his team has submitted an update to the previous medRxiv preprint and is waiting for approval.

Regardless of health status, men do worse with COVID-19

Men appear more likely than women to experience severe outcomes from COVID-19 regardless of whether the men have underlying health conditions, according to a new study. Researchers in New York City who tracked roughly 5,000 patients of both sexes who were diagnosed in early 2020 found that men were sicker when first diagnosed and had a higher need for intensive care treatment and higher rates of death than women. This was true even though the men on average were younger and less likely than women to have risk factors such as obesity and high blood pressure that previously have been linked with poor COVID-19 outcomes. Among women, the likelihood of severe COVID-19 outcomes did seem to be related to their health status, the researchers said in a report published on Wednesday in the journal Communications Medicine. A second analysis of another group of roughly 1,600 patients in New York City diagnosed later in the year showed similar patterns. The authors noted that because their information on patients’ pre-existing medical problems may have been incomplete, larger studies are needed to confirm their findings and to explain the causes.

Moderna vaccine antibodies neutralize variants in lab study

The mRNA vaccine from Moderna Inc can defend against emerging variants with only modestly reduced effectiveness, laboratory experiments indicated. Moderna researchers studied blood serum obtained from eight volunteers who had received the second dose of the vaccine a week earlier. They found the vaccine had produced antibodies capable of neutralizing all variants, including additional versions of the Beta variant first identified in South Africa and three lineages of variants first identified in India, including the Kappa and Delta variants. The analysis did show some reduction of neutralization, by 2.1 fold against Delta, 3.3-3.4 fold against Kappa and 3.2 fold against Gamma, which was first identified in Brazil. “These new data are encouraging and reinforce our belief that the Moderna COVID-19 vaccine should remain protective against newly detected variants,” Moderna Chief Executive Stéphane Bancel said. The Moderna data was posted on Monday on the bioRxiv medical website ahead of peer review. Earlier in June, researchers reported in the journal Nature that the mRNA vaccine from Pfizer and BioNTech elicited antibodies that could neutralize all tested variants, including Delta, although at reduced strength.

(Reporting by Nancy Lapid and Mrinalika Roy; Editing by Will Dunham)

Oil firms as demand hopes outweigh rise of COVID-19 variant

By Noah Browning

LONDON (Reuters) – Oil prices rose on Tuesday as broad hopes for a demand recovery persisted despite new outbreaks of the highly contagious Delta variant of the coronavirus prompting fresh mobility curbs worldwide.

Brent crude futures were up 50 cents, or 0.7%, at $75.18 a barrel by 1400 GMT, having slumped by 2% on Monday.

U.S. West Texas Intermediate (WTI) crude futures rose 55 cents, or 0.8%, to $73.46 after a 1.5% retreat on Monday.

“From a global perspective, there are seemingly growing concerns over the increase in the COVID-19 Delta variant,” said StoneX analyst Kevin Solomon.

“The market has grown relatively immune to COVID-19 developments, but if lockdowns occur in larger demand centers in Asia, we may see the market’s nonchalance abate.”

Spain and Portugal, favorite summer holiday destinations for Europeans, imposed new restrictions on unvaccinated Britons on Monday, while Australians also faced tighter curbs owing to flare-ups of the virus across the country.

However, the market still expects the rollout of vaccination programs to brighten the demand outlook, analysts said.

“The narrative of the past few months has not changed: the war against the virus is being gradually won, the global economy and oil demand are recovering,” said PVM Oil analyst Tamas Varga.

“Oil supply is being effectively managed. Therefore dips are probably viewed by ardent bulls as attractive buying opportunities.”

The virus flare-up comes as the Organization of the Petroleum Exporting Countries (OPEC), Russia and allies, together known as OPEC+, are set to meet on July 1 to discuss easing their supply curbs.

OPEC’s demand forecasts show that in the fourth quarter global oil supply will fall short of demand by 2.2 million barrels per day (bpd), giving the producers some room to agree to add output.

Analysts expect OPEC+ to step up supply in August because the market has tightened on strong growth in fuel demand in the United States and China, the world’s two biggest oil consumers.

Investors will be looking to the latest U.S. inventory data for cues on the demand outlook. Crude stocks are likely to have extended their fall for a sixth straight week while gasoline stocks are also expected to have declined, a preliminary Reuters poll showed.

(Additional reporting by Sonali Paul; Editing by David Evans and David Goodman)

Brazil detects first case of South African variant as COVID-19 deaths soar

By Pedro Fonseca

RIO DE JANEIRO (Reuters) – Brazil has recorded its first confirmed case of the highly contagious coronavirus variant discovered in South Africa, a fresh danger sign for a country already ravaged by the world’s highest daily death toll fueled by a widespread local variant.

Last week, scientists at the Butantan biomedical institute said the case, identified in a woman in Sao Paulo state, might be a new local variant. Further analysis confirmed it as the first known local case of the variant widely circulating in South Africa and elsewhere.

Scientists fear a showdown between the South African variant and the already rampant Brazilian variant, known as P.1, both of which are more contagious and possibly more deadly than the original version of the coronavirus and have led to accelerated COVID-19 surges.

“It could be a huge duel,” said Maria Carolina Sabbaga, one of Butantan’s coordinators for studying new variants. “I think P.1 has already taken over. I’m not sure if the South African will overtake P.1, let’s see.”

The South African variant in studies appears to lessen protection from current vaccines.

Brazil is in the midst of a brutal COVID-19 wave, setting records for deaths on a weekly basis. On Tuesday, the Health Ministry reported a single-day record of 4,195 deaths.

The outbreak in South America’s largest country may overtake the United States to become the world’s deadliest, some medical experts predict.

José Patané, a Butantan researcher, said the South African variant most likely arrived in Brazil after traveling through Europe toward the end of 2020.

The first local diagnosis, a woman in her 30s in the city of Sorocaba, had not traveled abroad or come into contact with someone who did, indicating local community transmission, researchers said.

SLOW VACCINE ROLLOUT

A possible surge of the South African variant could further complicate Brazil’s slow vaccine rollout.

Brazil’s COVID-19 immunization program is built around the vaccines from AstraZeneca Plc and China’s Sinovac Biotech Ltd, which have proven effective against the Brazilian variant in preliminary studies, according to officials.

Research released on Wednesday showed the Sinovac shot was 50% effective at preventing symptomatic COVID-19 in a study of nearly 68,000 health workers in Manaus, where the P.1 strain first emerged as the predominant variant. The results support preliminary findings of separate research reported by Reuters last month.

In studies, the South African variant appears to lower the level of protection offered by the AstraZeneca shot and other available vaccines.

Immunizations have been slow to ramp up in Brazil after the government dragged its feet last year in acquiring vaccines while other countries raced to secure supplies.

President Jair Bolsonaro has shifted his tone on vaccines, touting shots he had until recently disdained. But the far-right former army captain continues to oppose social distancing and mask requirements that health experts see as essential for curbing virus transmission.

Under pressure from business leaders desperate to vaccinate their workforces and reopen operations, the lower house of Congress has taken up a controversial bill to allow private-sector vaccine purchases.

A version of the bill, first passed on Tuesday, would allow businesses to acquire vaccines to inoculate their employees as long as they donate the same number of shots to the public health system. Under current rules, businesses could only do that once the country has fully vaccinated risk groups outlined in a national immunization plan.

Proposed amendments to new legislation are still pending in the lower house before the bill goes to the Senate.

Bolsonaro is set to meet with a group of business leaders including BTG Pactual founder Andre Esteves and Banco Bradesco Chairman Luiz Carlos Trabuco Cappi later on Wednesday, local media reported, with the private vaccine dose plan among the items on the agenda.

(Reporting by Pedro Fonseca; Writing by Jake Spring; Editing by Brad Haynes and Bill Berkrot)

Life upended for Americans as U.S. scrambles to contain coronavirus threat

By Jonathan Allen and Steve Holland

NEW YORK/WASHINGTON (Reuters) – From Disneyland to the U.S. Supreme Court, from Wall Street to Dodgers Stadium, nearly every facet of American life fell into turmoil on Thursday as the coronavirus outbreak caused sweeping closures and economic disruption.

As concern grew over a rapid spread of the sometimes-fatal COVID-19 respiratory illness caused by the virus, the U.S. stock market cratered anew, professional and college sports leagues suspended play, Broadway theaters went dark and many schools from Ohio to Texas shuttered.

The unprecedented cascade of shutdowns reflected growing fears that the outbreak of the highly contagious pathogen, which has already killed at least 40 people in the United States, could race out of control unless authorities squelch large public gatherings.

As companies locked their offices and sent employees to work from home, fears of a recession rose in step with the number of U.S. infections, which jumped to more than 1,300 on Thursday. The concerns were reflected in U.S. stock markets, with major indexes now in bear-market territory – down at least 20% from their recent high.

New York City Mayor Bill de Blasio declared a state of emergency, granting him new powers as the number of confirmed cases rose to 95 in the nation’s most populous city.

“We are getting into a situation where the only analogy is war and a wartime dynamic,” de Blasio said, referring to an expected surge in demand for hospital beds.

From California to New York, officials banned large gatherings and closed museums and other institutions without saying how long the directives would stay in place, compounding the uncertainty.

After the Trump administration imposed sweeping restrictions on air travel between the United States and Europe, Gabriella Ribeiro, a Wayne, New Jersey-based travel consultant, said she was fielding a flood of panicked calls from customers.

“We call it the ‘C’ word,” Ribeiro said of coronavirus. “We’ve been through Ebola and SARS, but I haven’t seen this level of panic among travelers since 9/11.”

CANCELED: MARCH MADNESS AND BASEBALL

With cancellations hitting everything from Little League baseball to school fairs, the rituals of American life started to grind to a halt.

The NCAA canceled its annual “March Madness” college basketball tournament. Professional hockey and basketball seasons were halted indefinitely. Major League Baseball ended spring training and suspended the first two weeks of the season.

“Opening day is religion around here,” said Frank Buscemi, a self-described sports junkie and Detroit Tigers baseball fan. “It makes sense, and you’ve got to err on the side of caution – we get that. It doesn’t make it any easier and it doesn’t make it any more fun.”

Officials in hard-hit areas, including New York and Washington states, sought to balance the need to protect the public without crippling economic activity.

New York state banned gatherings of more than 500 people beginning on Friday, Governor Andrew Cuomo told reporters. California placed the cap at gatherings of 250 people.

Hollywood postponed the release of several movies and theaters around the world closed over the health crisis.

The Walt Disney Company shuttered their large U.S. properties, including Disneyland in California and Disney World in Florida.

In Washington, D.C., officials closed the U.S. Capitol complex to the public after a staffer for a senator from Washington state tested positive for the coronavirus. [L1N2B50S4] The Supreme Court closed to the public indefinitely, and the Kennedy Center canceled all performances.

Oscar-winning actor Tom Hanks and at least one player in the National Basketball Association announced that they had tested positive for the coronavirus.

“WE’RE NOT SET UP”

The patchwork of state and local directives to stem the tide of infections came as U.S. health officials struggled to expand the country’s limited testing capacity.

“The system is not really geared to what we need right now,” Anthony Fauci, the top U.S. official on infectious diseases, said at a congressional hearing. “The idea of anybody getting it (testing) easily the way people in other countries are doing it, we’re not set up for that.”

Two U.S. senators, Rick Scott and Lindsey Graham, opted for self-quarantine after interacting with a delegation led by Brazilian President Jair Bolsonaro in Florida. One of Bolsonaro’s team has tested positive for the virus.

President Donald Trump and Vice President Mike Pence also met the Brazilian delegation, but White House spokeswoman Stephanie Grisham said both of them had “almost no interactions with the individual who tested positive and do not require being tested at this time.”

Republicans initially balked at a sweeping coronavirus economic aid package crafted by Democrats in the House of Representatives. After a day-long negotiating session, House Speaker Nancy Pelosi said late Thursday that they were close to a deal with the administration.

The Senate canceled a scheduled recess and will return next week to work on legislation.

The Trump administration spelled out details of new rules on U.S. citizens and permanent residents’ returning from Europe under restrictions that ban most Europeans from entering the United States.

“Americans coming home will be funneled through 13 different airports, they’ll be screened, and then we’re going to ask every single American and legal resident returning to the United States to self-quarantine for 14 days,” Pence said.

Trump defended his decision, which goes into effect at midnight on Friday and lasts for 30 days. He said the ban could be lengthened or shortened.

The restrictions will heap pressure on airlines already reeling from the pandemic, hitting European carriers the hardest, analysts said.

American Airlines Inc <AAL.O> and Delta Air Lines Inc <DAL.N> said they were capping fares for U.S.-bound flights from Europe amid reports of exorbitant pricing as U.S. citizens flocked to European airports trying to return home.

(Reporting by Jonathan Allen and Steve Holland; Additional reporting by Susan Heavey, Lisa Lambert, Patricia Zengerle, David Morgan and Richard Cowan in Washington and Maria Caspani, Michael Erman and Dan Burns in New York, Steve Gorman in Culver City, California; Writing by Ginger Gibson and Paul Simao; Editing by Sonya Hepinstall, Cynthia Osterman, Leslie Adler and Daniel Wallis)