One ventilator, two patients: New York hospitals shift to crisis mode

By Jonathan Allen and Nick Brown

NEW YORK (Reuters) – At least one New York hospital has begun putting two patients on a single ventilator machine, an experimental crisis-mode protocol some doctors worry is too risky but others deemed necessary as the coronavirus outbreak strains medical resources.

The coronavirus causes a respiratory illness called COVID-19 that in severe cases can ravage the lungs. It has killed at least 281 people over a few weeks in New York City, which is struggling with one of the largest caseloads in the world at nearly 22,000 confirmed cases.

A tool of last resort that involves threading a tube down a patient’s windpipe, a mechanical ventilator can sustain a person who can no longer breathe unaided. The city only has a few thousand and is trying to find tens of thousands more.

Dr. Craig Smith, surgeon-in-chief at New York-Presbyterian/Columbia University Medical Center in Manhattan, wrote in a newsletter to staff that anesthesiology and intensive care teams had worked “day and night” to get the split-ventilation experiment going.

By Wednesday, he wrote, there were “two patients being carefully managed on one ventilator.”

New York Governor Andrew Cuomo, who says his staff is struggling to find enough machines on the market, has touted the adaptation as a potential life-saver. “It’s not ideal,” he told reporters, “but we believe it’s workable.”

The U.S. Food & Drug Administration, which regulates medical device manufacturers, gave emergency authorization on Tuesday allowing ventilators to be modified using a splitter tube to serve multiple COVID-19 patients, though manufacturers still must share safety information with regulators.

Some medical associations oppose the unproven method.

On Thursday, the Society of Critical Care Medicine, the American Association for Respiratory Care and four other practitioner groups issued a joint statement saying the practice “should not be attempted because it cannot be done safely with current equipment.”

It is difficult enough to fine-tune a ventilator to keep alive even one patient with acute respiratory distress syndrome (ARDS), the statement said; sharing it across multiple patients would worsen outcomes for all. They proposed doctors instead choose the one patient per ventilator deemed most likely to survive.

At Columbia, Smith noted that they could not split a ventilator across just any two COVID-19 patients, but were only pairing patients with sufficiently similar respiratory needs.

Across Manhattan, Mount Sinai Hospital told staff in an email that officials were “working to figure out” whether they could split ventilators. The hospital has ordered the necessary adapters, a nurse there said in an interview on condition of anonymity because she was not authorized to speak to reporters.

Experts at Columbia pointed to a 2006 study where researchers, using lung simulators, concluded that a single ventilator could sustain four adults in an emergency scenario.

One author of that study, Dr. Greg Neyman, cautioned against the application in COVID-19 cases in part because the lungs themselves are infected. If one patient’s lungs were deteriorating faster, he said, it could cause imbalances in the closed system. One patient could starve for oxygen while the other patient’s lungs would get increased pressure.

“Unless they were very very closely monitored, such a set up may end up doing more harm than good,” Neyman wrote in an email to Reuters.

(Reporting by Jonathan Allen and Nick Brown; Editing by David Gregorio)

U.S. in crisis mode as coronavirus cases soar, travel restrictions loom

Reuters
By Steve Holland and Susan Heavey

WASHINGTON (Reuters) – The United States went into crisis mode on Thursday to contain a coronavirus outbreak that has played havoc with businesses, shuttered schools and universities and severely disrupted the sports and entertainment world.

Fears of a recession grew as U.S. cases of the virus that causes the sometimes fatal COVID-19 respiratory illness rose and the Trump administration prepared to roll out restrictions that threaten to cripple the travel industry.

U.S. stock markets cratered again after trading opened, with major indexes entering bear-market territory.

Officials in the hardest-hit parts of the country, including New York and Washington states, were trying to balance the need to protect the public while stopping short of actions that could freeze the daily lives of millions of people and stop economic activity.

New York City Mayor Bill de Blasio told CNN that “more and more restrictions” were likely on the way, though he said there were no plans to shut down the city’s famous theater district or its subway system, a vital transportation link.

“I don’t want to see Broadway go dark,” de Blasio said, adding that authorities will be issuing further guidance either on Thursday or Friday. He also announced the closure of two schools in the city due to a student’s “self-confirmed” positive case of COVID-19.

Hollywood has postponed the release of several movies and movie theaters around the world have been closed over the health crisis.

More than 1,300 U.S. cases of coronavirus have been confirmed and 33 people have died, according to a tally by Johns Hopkins University in Baltimore. A nursing home in Kirkland, Washington, has accounted for a large share of the deaths.

U.S. health officials have struggled to quickly expand testing capacity to make screening for the virus widely available, and have acknowledged that it is not easy for those possibly exposed to the virus to get tested.

“The system is not really geared to what we need right now,” Anthony Fauci, the top U.S. official on infectious diseases, said at a congressional hearing. “The idea of anybody getting it (testing) easily the way people in other countries are doing it, we’re not set up for that.”

Oscar-winning actor Tom Hanks and at least one player in the National Basketball Association are among those who have been infected with the highly infectious coronavirus, which can lead to pneumonia and other respiratory problems, especially in the elderly and those with compromised immune systems.

The NBA has suspended its season until further notice.

Harvard and Princeton are among the universities that have announced they will move to virtual classroom instruction after the spring break later this month.

‘SELF-QUARANTINE’

U.S. citizens and permanent residents returning from abroad will be screened for the virus and asked to go into “self-quarantine” for 14 days, Vice President Mike Pence said in an interview with CNN.

“Americans coming home will be funneled through 13 different airports, they’ll be screened, and then we’re going to ask every single American and legal resident returning to the United States to self-quarantine for 14 days,” Pence said.

President Donald Trump defended his decision to impose a 30-day restriction on travel from Europe, except Britain and Ireland, that goes into effect at midnight on Friday.

Speaking to reporters in the White House alongside Irish Prime Minister Leo Varadkar, he said the ban could be lengthened or shortened, and added that he had been unable to consult with the European Union prior to announcing it on Wednesday night.

The travel restrictions will heap more pressure on airlines already reeling from the pandemic, hitting European carriers the hardest, analysts said. Global stock markets sank again on Thursday.

The S&P 500 <.SPX> and the Nasdaq <.IXIC> indexes entered into a bear market. The S&P 500 plunged more than 8% and the Dow Jones Industrial Average <.DJI> was down 4.3%. Airline and some cruise line stocks were particularly hard hit.

The U.S. House of Representatives plans to vote on Democrats’ sweeping coronavirus bill on Thursday, according to a Democratic aide.

Republicans have balked at the plan and called for a delay in considering the proposed legislation, and Trump said on Thursday he didn’t support the bill.

Instead, Trump has pushed for a payroll tax cut and instructed the Treasury Department to defer tax payments without interest or penalties for certain business and individuals hit by the health crisis.

The president also backs emergency action to provide financial relief for workers who are ill, quarantined or caring for others due to coronavirus.

(Reporting by Steve Holland, Susan Heavey, Lisa Lambert and Richard Cowan in Washington and Maria Caspani and Michael Erman in New York; Writing by Paul Simao; Editing by Jonathan Oatis and Sonya Hepinstall)