Britain tightens borders to keep out new COVID-19 strains

LONDON (Reuters) – Britain is tightening border controls to prevent new strains of COVID-19 coming into the country, suspending all the ‘travel corridor’ arrangements that had meant arrivals from some countries did not need to quarantine.

The change comes into force at 0400 GMT on Monday and means all passengers must have a recent negative coronavirus test and transfer immediately into isolation upon arrival. The isolation period lasts for 10 days, unless the passenger tests negative after five days.

Prime Minister Boris Johnson made the announcement during a news conference when he praised the country’s vaccination program, but he also warned: “What we don’t want to see is all that hard work undone by the arrival of a new variant that is vaccine busting.”

On Thursday, Britain banned arrivals from South America, Portugal and some other countries over fears about a strain of the virus detected in Brazil.

Britain has already felt the effects of mutations in the virus first hand. A strain first discovered in England has proved to be more transmissible and a major factor behind a spike in cases across the country.

(Reporting by Sarah Young, Writing by William James, editing by Elizabeth Piper)

Britain tells shoppers food is plentiful but supermarkets fret about next week

By James Davey

LONDON (Reuters) – Britain said there was plenty of food in the shops on Tuesday but industry groups repeated warnings of shortages of some fresh produce from next week unless freight routes to mainland Europe are swiftly restored.

Interior minister Priti Patel said Britons should not be concerned despite Tesco and Sainsbury’s, Britain’s two biggest supermarket groups, raising the alarm on Monday that gaps could start to appear on fruit and vegetable shelves within days.

Freight from France is being disrupted as part of a wider suspension of travel links with Britain to try to curb a new faster-spreading strain of COVID-19.

“I don’t think anybody should be worried – there is plenty of food in our shops,” Patel told LBC radio.

British supermarkets are facing record Christmas demand due to COVID-19 restrictions on the hospitality industry and on travel and there are fears of panic buying.

“UK shoppers need have no concerns about food supplies over Christmas, but impacts on local on-shelf availability of certain fresh foods look likely from next week unless we can swiftly restore this link,” said Ian Wright, CEO of the Food and Drink Federation, which represents over 300 food and drink businesses.

The British Retail Consortium (BRC), which represents more than 170 major retailers including the big supermarkets, is also concerned about supplies shortly after Christmas, highlighting possible shortages of salad, vegetables and fruit, including raspberries and strawberries.

“The borders really need to be running pretty much freely from tomorrow to assure us that there won’t be any disruption,” Andrew Opie, the BRC’s director of food and sustainability, told BBC radio.

He noted that 90% of the lettuces consumed by Britons and about 70% of soft fruit comes through the Channel ports at this time of year.

TESTING

The BBC cited France’s Europe Minister Clément Beaune as saying that Britain and France would announce a deal to restart freight by Wednesday. One option is to roll out mass testing for truck drivers.

“Whatever is agreed, we need to be careful it doesn’t add too much friction to the supply chain which in itself causes disruption by causing delays to the drivers whilst they’re being tested,” said Opie.

Though large queues again snaked around supermarkets across Britain on Tuesday and some shelves were stripped bare, food retailers said they had not seen any major changes in customer buying behavior.

Opie said supermarkets had expected and planned for Christmas queues.

“You need to remember these are the busiest days for shopping…and remember all the stores are still operating all of their COVID protocols, which means you can’t get as many people into a supermarket as you would do normally,” Opie said.

“We’re not seeing the sort of excessive buying in any kind of volumes that we saw around that period in sort of mid-March,” he added.

(Reporting by James Davey; Editing by Guy Faulconbridge, Alexander Smith and Louise Heavens)

Anger grows as truckers stranded in England miss Christmas at home

By Ben Makori and Gerhard Mey

DOVER, England (Reuters) – Dan Jinca, a Romanian truck driver stranded in England after much of the world shut its borders to Britain, is angry, and he is not alone.

The 47-year-old will miss Christmas at home and he thinks the official excuse for the border closures – a new variant of the novel coronavirus spreading fast across southern England – is nonsense.

“We are upset and we don’t know why we have to be in this situation,” Jinca told Reuters, speaking English. “They say it is about corona. We don’t know.”

Hundreds of trucks are lined up, snaking into the horizon across southern England after the border closures. Many drivers have been stuck for days, eating up their reserves of food along roads that now stand silent.

No matter what is decided in London, Paris and Brussels, Jinca, a father, will miss Christmas at home in Bumbești-Jiu, about 186 miles (300 km) west of Bucharest, because he has too far to drive.

“Now it is done, it is finished. From here to go home we have about 2,000 miles,” he said. “It is about 45 hours to drive non-stop – no sleep, just drive. We can’t make it.”

After 7 years in trucking, it has never happened to him before.

Sergio Robles, a 41-year-old Spanish truck driver, said the conditions – stuck on a road in December for three days and counting – were a disgrace.

And he wants a solution – and information – fast.

“They don’t give us food, they don’t give us drinks, they don’t give us sanitation, they don’t offer us anything,” he said in Spanish. “The situation is basically inhumane, so what we are asking for is a solution.”

“I think and believe that this happening now isn’t due to coronavirus or anything, it’s due to Brexit, due to internal politics or something of that manner.”

Robles will also miss Christmas with his family in Madrid.

“We are the transport that moves the world, so to say. And they treat us badly,” he said.

“They treat us as if we are garbage. We don’t get to spend Christmas at home, not with family or children or anything. I think there’s nothing right in all of this.”

(Writing by Guy Faulconbridge; Editing by Mike Collett-White)

WHO says no need for major alarm over new coronavirus strain

By Emma Farge and Michael Shields

GENEVA/ZURICH (Reuters) – The World Health Organization cautioned against major alarm over a new, highly infectious variant of the coronavirus that has emerged in Britain, saying this was a normal part of a pandemic’s evolution.

WHO officials even put a positive light on the discovery of the new strains that prompted a slew of alarmed countries to impose travel restrictions on Britain and South Africa, saying new tools to track the virus were working.

“We have to find a balance. It’s very important to have transparency, it’s very important to tell the public the way it is, but it’s also important to get across that this is a normal part of virus evolution,” WHO emergencies chief Mike Ryan told an online briefing.

“Being able to track a virus this closely, this carefully, this scientifically in real time is a real positive development for global public health, and the countries doing this type of surveillance should be commended.”

Citing data from Britain, WHO officials said they had no evidence that the variant made people sicker or was more deadly than existing strains of COVID-19, although it did seem to spread more easily.

Countries imposing travel curbs were acting out of an abundance of caution while they assess risks, Ryan said, adding: “That is prudent. But it is also important that everyone recognizes that this happens, these variants occur.”

WHO officials said coronavirus mutations had so far been much slower than with influenza and that even the new UK variant remained much less transmissible than other diseases like mumps.

They said vaccines developed to combat COVID-19 should handle the new variants as well, although checks were under way to ensure this was the case.

“So far, even though we have seen a number of changes, a number of mutations, none has made a significant impact on either the susceptibility of the virus to any of the currently used therapeutics, drugs or the vaccines under development and one hopes that will continue to be the case,” WHO Chief Scientist Soumya Swaminathan told the briefing.

The WHO said it expects to get more detail within days or weeks on the potential impact of the highly transmissible new coronavirus strain.

(Reporting by Emma Farge in Geneva and Michael Shields in Zurich; Writing by Josephine Mason; editing by Mark Heinrich)

Shaken by new coronavirus strain, world shuts the door on Britain

By Gerhard Mey and Ben Makori

DOVER, England (Reuters) – Several countries closed their borders to Britain on Monday over fears of a highly infectious new coronavirus strain, causing travel chaos and raising the prospect of food shortages just days before the UK is set to leave the European Union.

India, Pakistan, Poland, Spain, Switzerland, Sweden, Russia, Jordan and Hong Kong suspended travel for Britons after Prime Minister Boris Johnson warned a mutated variant of the virus, up to 70% more transmissible, had been identified in the country. Saudi Arabia, Kuwait and Oman closed their borders completely.

Several other nations blocked travel from Britain over the weekend, including France, Germany, Italy, the Netherlands, Austria, Ireland, Belgium and Canada – although experts said the strain may already be circulating in countries with less advanced detection methods than the United Kingdom.

The discovery of the new strain, just months before vaccines are expected to be widely available, sowed fresh panic in a pandemic that has killed about 1.7 million people worldwide and more than 67,000 in Britain.

New York Governor Andrew Cuomo urged the U.S. government to take steps to prevent the variant entering the country, which has been worst hit by COVID-19 with almost 318,000 deaths.

“It’s high time the federal government takes swift action, because today that variant is getting on a plane and landing in JFK, and all it takes is one person,” he said.

U.S. Assistant Health Secretary Brett Giroir said nothing had yet been decided on any travel ban. As the pandemic accelerates there, Congress was poised to vote on a $900 billion COVID-19 stimulus package, after months of inaction.

EU officials met via video link to coordinate their response to the new strain of the coronavirus. The bloc is on course to start COVID-19 vaccinations within a week after its medicines regulator approved the use of a shot from Pfizer and BioNTech on Monday.

Experts said there was no evidence that vaccines would not protect against this variant, but added they were working around the clock to determine whether the mutations would affect how well the shots guarded against infection.

“Since the three vaccine forerunners target the spike protein, how the variant responds to the vaccines and the protection that the vaccine will offer does still need to be examined in detail,” said Saad Shakir, a professor and director at Britain’s drug safety research unit.

FOOD SHORTAGES WARNING

France shut its border to arrivals of people and trucks from Britain, closing off one of the most important trade arteries with mainland Europe.

“No driver wants to deliver to the UK now, so the UK is going to see its freight supply dry up,” France’s FNTR national road-haulage federation said.

As families and truck drivers tried to navigate the travel bans to get back home in time for Christmas, British supermarket chain Sainsbury’s said shortages would start to appear within days if transport ties were not quickly restored.

“If nothing changes, we will start to see gaps over the coming days on lettuce, some salad leaves, cauliflowers, broccoli and citrus fruit – all of which are imported from the continent at this time of year,” Sainsbury’s said.

The global alarm was reflected in financial markets.

European shares slumped, with travel and leisure stocks bearing the brunt; British Airways-owner IAG and easyJet dropped about 7%, while Air France KLM lost around 3%.

Wall Street also felt the pain, with losses across the board. The S&P 1500 airlines index slid 3%, while leading cruise operators fell about 4%.

The British pound tumbled 2.5% against the dollar at one point before paring some of the losses, while the yield on two-year UK government bonds hit a record low.

‘SICK MAN OF EUROPE’

Johnson cancelled Christmas plans for millions of British people on Saturday due to the more infectious strain of the coronavirus, though he said there was no evidence that it was either more lethal or caused a more severe illness.

Britain’s tabloids bemoaned the crisis.

“Sick Man of Europe,” the Daily Mirror newspaper said on its front page beside a picture of Johnson, while the Sun newspaper said “French show no merci.”

The new variant and restrictions in Britain compound the chaos as the country prepares to finally part ways with the European Union, possibly without a trade deal, when the Brexit transition period at 2300 GMT on Dec. 31.

Talks on a Brexit trade deal were due to continue on Monday.

The new variant, which scientists said was 40%-70% more transmissible, is rapidly become the dominant strain in parts of southern England, including London.

Experts tracking the new strain said there was some early but unconfirmed evidence that it could transmit as readily among children as among adults, unlike previous dominant strains that appeared to be more easily able to infect adults.

‘2020 NOT DONE WITH US’

Cases of the new strain have also been detected in some other countries, including Denmark, Italy and the Netherlands.

Australia said two people who travelled from the United Kingdom to New South Wales, its most populous state, were carrying the mutated virus. It axed dozens of domestic flights while New South Wales locked down more than 250,000 people.

“2020 is not done with us yet,” Prime Minister Scott Morrison said.

Some scientists said the prevalence discovered in Britain might be down to detection.

“Britain is simply the country which finds these mutations the most because they are looking for them more. There are countries that hardly search or do not search at all,” Marc Van Ranst, a virologist from the Rega Institute for Medical Research in Belgium, told broadcaster VRT.

“I think we will find in the coming days that a lot of other countries will find it.”

(Additional reporting by Kate Kelland, Toby Melville and James Davey in London, Laurence Frost in Paris, Philip Blenkinsop in Brussels, Sayantani Ghosh in Singapore, Frank McGurty in New York, Josh Smith and Sangmi Cha in Seoul, Renju Jose in Sydney, Shilpa Jamkhandikar in Mumbai and Farah Master in Hong Kong; Writing by Guy Faulconbridge and Pravin Char; Editing by Alison Williams and Mike Collett-White)

The new coronavirus variant in Britain: How worrying is it?

By Kate Kelland

LONDON (Reuters) – A new variant of the pandemic SARS-CoV-2 coronavirus is spreading rapidly in Britain and prompting high levels of concern among its European neighbors, some of which have cut transport links.

The strain, referred to by some experts as the B.1.1.7 lineage, is not the first new variant of the pandemic virus to emerge, but is said to be up to 70% more transmissible than the previously dominant strain in the United Kingdom.

ARE THE CONCERNS JUSTIFIED?

Most scientists say yes. The new variant has rapidly become the dominant strain in cases of COVID-19 in parts of southern England, and has been linked to an increase in hospitalization rates, especially in London and in the adjacent county of Kent.

While it was first seen in Britain in September, by the week of Dec. 9 in London, 62% of COVID-19 cases were due to the new variant. That compared to 28% of cases three weeks earlier.

The governments of Australia, Italy and the Netherlands say they detected cases of the new strain. It was identified in the Netherlands in early December.

A few cases of COVID-19 with the new variant have also been reported to the ECDC, Europe’s disease monitoring agency, by Iceland and Denmark. Media reports in Belgium say cases have also been detected there.

“It is right to take it seriously,” said Peter Openshaw, a professor of experimental medicine at Imperial College London. Shaun Fitzgerald, a visiting professor at the University of Cambridge, said the situation was “extremely concerning.”

WHY?

The main worry is that the variant is significantly more transmissible than the original strain. It has 23 mutations in its genetic code – a relatively high number of changes – and some of these are affecting its ability to spread.

Scientists say it is about 40%-70% more transmissible. The UK government said on Saturday it could increase the reproduction “R” rate by 0.4.

This means it is spreading faster in Britain, making the pandemic there yet harder to control and increasing the risk it will also spread swiftly in other countries.

“The new B.1.1.7 … still appears to have all the human lethality that the original had, but with an increased ability to transmit,” said Martin Hibberd, professor of emerging infectious disease at the London School of Hygiene & Tropical Medicine.

WILL COVID-19 VACCINES PROTECT AGAINST THIS VARIANT?

Scientists say there’s no evidence that vaccines currently being deployed in the UK – made by Pfizer and BioNtech – or other COVID-19 shots in development will not protect against this variant.

“It’s unlikely that this will have anything more than a minor, if any, effect on the vaccine’s effectiveness,” said Adam Finn, a vaccine specialist and professor of pediatrics at Bristol University.

Britain’s chief scientific adviser Patrick Vallance also said COVID-19 vaccines appeared to be adequate in generating an immune response to the variant of the coronavirus.

“We are not seeing…any gross changes in the spike protein that will reduce vaccine effectiveness so far,” said Julian Tang, professor and clinical virologist at Leicester University.

DOES THE NEW VARIANT AFFECT TESTING?

To some extent, yes.

One of the mutations in the new variant affects one of three genomic targets used by some PCR tests. This means that in those tests, that target area, or “channel”, would come up negative.

“This has affected the ability of some tests to detect the virus,” said Robert Shorten, an expert in microbiology at the Association for Clinical Biochemistry & Laboratory Medicine.

Since PCR tests generally detect more than one gene target, however, a mutation in the spike protein only partly affects the test, reducing that risk of false negative results.

ARE THERE OTHER SIGNIFICANT SARS-CoV-2 VARIANTS ABOUT?

Yes. Strains of the COVID-19-causing virus have emerged in recent months in South Africa, Spain, Denmark and other countries that have also raised concern.

However none, so far, has been found to contain mutations that make it more deadly, or more likely to be able to evade vaccines or treatments.

DID THIS NEW VARIANT ORIGINATE IN BRITAIN?

Vallance said on Saturday he thought the new variant might have started in the UK. Some scientists in Europe have credited British expertise in genomic surveillance for identifying the mutation.

“The UK has one of the most comprehensive genetic surveillance programs in the world – 5% to 10% all virus samples are genetically tested. Few countries do better,” Steven Van Gucht, head of viral diseases at the Belgian Institute of Health, told a news conference on Monday.

(Additional reporting by Philip Blenkinsop in Brussels, editing by Josephine Mason and Mark Heinrich)

In COVID-19 milestone for West, Britain starts mass vaccination

By Alistair Smout

LONDON (Reuters) – A 90-year-old grandmother became the world’s first person to receive a fully-tested COVID-19 shot on Tuesday, as Britain began mass-vaccinating its people in a global drive that poses one of the biggest logistical challenges in peacetime history.

Health workers started inoculating the most vulnerable with the vaccine developed by Pfizer and BioNTech, with the country a test case for the world as it contends with distributing a compound that must be stored at -70C (-94F).

Margaret Keenan, who turns 91 in a week, was the first to receive the shot, at a hospital in Coventry, central England.

“It’s the best early birthday present I could wish for because it means I can finally look forward to spending time with my family and friends in the new year after being on my own for most of the year,” she said.

The launch of the vaccine, one of three shots that have reported successful results from large trials, will fuel hope that the world may be turning a corner in the fight against a pandemic that has killed more than 1.5 million people.

Britain, the worst-hit in Europe with over 61,000 deaths, is the first Western nation to begin mass-vaccinations and the first globally to roll out the Pfizer/BioNTech shot.

But despite the relief of people receiving the first dose of the two-dose regimen, they will have to wait three weeks for their second shot, and there is no evidence immunization will reduce transmission of the virus.

“It will gradually make a huge, huge difference. But I stress gradually, because we’re not there yet. We haven’t defeated this virus yet,” Prime Minister Boris Johnson said.

Health Secretary Matt Hancock said he expected millions to be vaccinated by the end of the year, and described the start of the drive as “V-Day.” But he cautioned people should respect social-distancing rules until spring at least, when he hoped the most vulnerable people would be vaccinated.

The country has ordered enough supplies of the Pfizer/BioNTech shot to vaccinate 20 million people. The developers said it was 95% effective in preventing illness in final-stage trials.

Russia and China have both already started giving domestically produced vaccine candidates to their populations, though before final safety and efficacy trials have been completed.

FIVE DAYS IN A FRIDGE

In Britain, about 800,000 doses are expected to be available within the first week, with care-home residents and carers, the over-80s and some health workers prioritized. Hancock said he had a “high degree of confidence” Britain would take delivery of another batch of the vaccine next week.

“I know we’re absolutely bursting at the doors with COVID patients, so I more than anybody wants it to happen quickly,” said Ami Jones, a hospital intensive-care consultant from Wales who received the jab before going to work.

The country is relatively small with good infrastructure. Yet the logistical challenges in distributing the vaccine, which only lasts five days in a regular fridge, mean it will first go to dozens of hospitals and cannot yet be taken into care homes.

Bigger tests could await for the Pfizer/BioNTech shot, as well as a vaccine from Moderna, which was found to have a similar level of success in trials and is based on the same mRNA genetic technology that requires such ultra-cold storage.

Transport and distribution could prove more challenging in hot countries and bigger nations such as the United States and India, which have been worst-hit by COVID-19 and are expected to approve the shot for emergency use in the coming days or weeks.

South Korea, which has coped relatively well with the pandemic, sounded a note of caution, saying it would not hurry vaccine rollouts, partly to give it time to observe potential side-effects in other countries. Vaccinations may start in the first half of 2021, the health ministry added.

The third vaccine to have had trial success, developed by AstraZeneca and Oxford University, is viewed as offering one of the best hopes for many developing countries because it is cheaper and can be transported at normal fridge temperatures. Late-stage trials found it had an average success rate of 70%.

Britain hopes for regulatory approval of the Oxford/AstraZeneca shot in the next couple of weeks.

A SHOT FOR SHAKESPEARE

Britain approved the Pfizer/BioNTech vaccine for emergency use less than a week ago, and is rolling it out ahead of the United States and European Union.

The Pfizer/BioNTech vaccine is being imported from Belgium, while initial supplies of the AstraZeneca/Oxford shot are being shipped from Germany.

“Of course, it adds complexity,” Steve Bates, chief executive of the BioIndustry Association, told reporters of the possible impact of Brexit. “But there is a robust plan for alternative routes and mitigation.”

In total Britain has ordered 40 million doses of the Pfizer/BioNTech shot, enough to vaccinate 20 million people in the country of 67 million. It has ordered 357 million doses of seven different COVID-19 vaccines in all.

Amid the gravity of the pandemic, the vaccination on Tuesday of one William Shakespeare, an 81-year-old of Warwickshire in England, was greeted with humor on social media.

Twitter users joked about “The Taming of the Flu” and “The Two Gentlemen of Corona”. Some asked, if Margaret Keenan was patient 1A, was Shakespeare “Patient 2B or not 2B?”.

(Reporting by Alistair Smout; Additional reporting by Sarah Young, Kate Holton and Natalie Thomas; Editing by Guy Faulconbridge and Pravin Char)

In world first, UK approves Pfizer-BioNTech COVID-19 vaccine

By Guy Faulconbridge and Paul Sandle

LONDON (Reuters) – Britain approved Pfizer’s COVID-19 vaccine on Wednesday, jumping ahead of the rest of the world in the race to begin the most crucial mass inoculation program in history with a shot tested in wide-scale clinical trials.

Prime Minister Boris Johnson touted the greenlight from the UK’s medicine authority as a global win and a ray of hope amid a pandemic, though he recognized the logistical challenges of vaccinating an entire country of 67 million.

Britain’s move raised hopes that tide could soon turn against a virus which has killed nearly 1.5 million people, hammered the world economy and upended normal life for billions.

Britain’s Medicines and Healthcare products Regulatory Agency (MHRA) granted emergency use approval to the Pfizer-BioNTech vaccine, which they say is 95% effective in preventing illness, just 23 days since Pfizer published the first data from its final stage clinical trial.

“Fantastic news,” Johnson told parliament, though he cautioned that people should not get too carried away.

“At this stage it is very, very important that people do not get their hopes up too soon about the speed with which we will be able to roll out this vaccine.”

The world’s big powers have been racing for a vaccine for months to begin the long road to recovery, and getting there first may be seen as a coup for Johnson’s government, which has faced criticism over its handling of the crisis.

The approval of a shot for use close to a year since the novel coronavirus emerged in Wuhan, China, is a triumph for science, Pfizer boss Albert Bourla and his German biotechnology partner BioNTech.

Both the United States and the European Union’s regulator are sifting through the same Pfizer vaccine trial data, but have not yet given their approval.

Britain’s breakneck speed drew criticism from Brussels where, in an unusually blunt statement, the EU’s drugs regulator said its longer procedure was more appropriate as it was based on more evidence and required more checks.

British leaders said that, while they would love to get a shot themselves, priority had to be given to those most in need – the elderly, those in care homes and health workers.

Amid the celebratory rhetoric, Germany’s ambassador to Britain Andreas Michaelis publicly scolded a British minister for presenting it as a national triumph.

“I really don’t think this is a national story. In spite of the German company BioNTech having made a crucial contribution, this is European and transatlantic,” Michaelis said.

‘NO CORNERS CUT’

The U.S. drugmaker said Britain’s emergency use authorization marked a historic moment in the fight against COVID-19. Pfizer announced its vaccine breakthrough on Nov. 9 with stage III clinical trial results.

“This authorization is a goal we have been working toward since we first declared that science will win, and we applaud the MHRA for their ability to conduct a careful assessment and take timely action to help protect the people of the UK,” said CEO Bourla.

Britain’s medicines regulator approved the vaccine in record time by doing a “rolling” concurrent analysis of data and the manufacturing process while Pfizer raced to conclude trials.

“No corners have been cut,” MHRA chief June Raine said in a televised briefing from Downing Street, adding that the first data on the vaccine had been received in June and undergone a rigorous analysis to international standards. “Safety is our watchword.”

“With 450 people dying of COVID-19 infection every day in the UK, the benefits of rapid vaccine approval outweigh the potential risks,” said Andrew Hill, senior visiting research fellow in the Department of Pharmacology at the University of Liverpool.

The U.S. Food and Drug Administration (FDA) will make a decision on emergency use authorization on the Pfizer/BioNTech vaccine in days or weeks after a panel of outside advisors meets on Dec. 10 to discuss whether to recommend it. The FDA often but not always follows the panel’s advice.

The European Medicines Agency (EMA) said it could give emergency approval for the shot by Dec. 29.

“The data submitted to regulatory agencies around the world are the result of a scientifically rigorous and highly ethical research and development program,” said Ugur Sahin, chief executive and co-founder of BioNTech.

BioNTech said it expected FDA and EMA to make a decision in mid-December.

Anti-poverty campaigners, meanwhile, warned against rich countries hoarding vaccines at the expense of poorer ones. “The worst thing we can do at this moment is allow a small number of countries to monopolize access to vaccines like this,” said Romilly Greenhill, UK director of the ONE organization.

FIRST IN LINE?

Britain said it would start vaccinating those most at risk of dying early next week after it gets 800,000 doses from Pfizer’s manufacturing center in Belgium.

“I strongly urge people to take up the vaccine but it is no part of our culture or our ambition in this country to make vaccines mandatory,” Johnson said.

The speed of the rollout depends on how fast Pfizer can manufacture and deliver the vaccine – and the extreme temperature of -70C (-94F) at which the vaccine must be stored.

Britain has ordered 40 million doses of the Pfizer vaccine – enough for just under a third of the population as two shots are needed per person to gain immunity.

Health Secretary Matt Hancock said hospitals were ready to receive the shots and vaccination centers would be set up across the country, but he admitted distribution would be a challenge given storage at temperature typical of an Antarctic winter.

Pfizer has said the shots can be kept in thermal shipping boxes for up to 30 days. Afterwards, the vaccine can be kept at fridge temperatures for up to five days.

Other frontrunners in the vaccine race include U.S. biotech firm Moderna, which has said its shot was 94% successful in late-stage clinical trials, and AstraZeneca, which said last month its COVID-19 shot was 70% effective in pivotal trials and could be up to 90% effective.

(Reporting by Guy Faulconbridge and Paul Sandle; Additional reporting by Kate Kelland, Alistair Smout and Estelle Shirgon; Editing by Kate Holton, Carmel Crimmins, Alex Richardson and Nick Macfie)

Britain hopes Christmas can be saved as COVID cases flatten

LONDON (Reuters) – Britain could ease stringent COVID-19 rules to allow families to gather for Christmas as signs indicate that coronavirus cases are starting to flatten as a result of current lockdowns, Health Secretary Matt Hancock said on Friday.

The United Kingdom has the worst official COVID-19 death toll in Europe and Prime Minister Boris Johnson has imposed some of the most stringent curbs in peacetime history in an attempt to halt the spread of the coronavirus.

But heading into the holiday season, the government faces a dilemma – to ease restrictions, with the risk of renewed spread of the disease and death, or to ban large get-togethers.

“It of course won’t be like a normal Christmas, there will have to be rules in place,” Hancock told Sky News.

He said he hoped that restrictions, which include a strict lockdown in England, could be eased to “allow for a bit more of that normal Christmas that people really look forward to”.

Hancock said he was working with the devolved administrations in Scotland, Wales and Northern Ireland – which manage their own policies on combating the pandemic – for a UK-wide approach to rules for Christmas.

The head of London’s Metropolitan Police, Cressida Dick, said that while police might try to stop wild parties, there were better uses of police time than trying to catch families out.

“Let’s see what the rules are, but I have no interest in interrupting family Christmas dinners,” she told LBC radio.

There was some sign that infection numbers were flattening. The Office for National Statistics said incidence had levelled off in recent weeks, with daily infections increasing by 38,900 in England in the latest week, down from around 50,000 previously.

The government also reduced their estimate of the reproduction “R” number, and said the daily growth rate had fallen to between 0% and 2%.

England has been under lockdown for two weeks. It is due to end on Dec. 2, although ministers have not ruled out that it could be extended.

Scotland’s biggest city Glasgow and parts of the nation’s west and central regions begin a stricter lockdown regime on Friday to last until Dec. 11, including the closure of pubs and restaurants and non-essential shops.

(Reporting by Alistair Smout, Sarah Young, Kate Holton and Michael Holden, editing by Guy Faulconbridge and Angus MacSwan)

Europe COVID death toll tops 300,000 as winter looms and infections surge

By Shaina Ahluwalia, Anurag Maan and Roshan Abraham

(Reuters) – More than 300,000 people have died of COVID-19 across Europe, according to a Reuters tally on Tuesday, and authorities fear that fatalities and infections will continue to rise as the region heads into winter despite hopes for a new vaccine.

With just 10% of the world’s population, Europe accounts for almost a quarter of the 1.2 million deaths globally, and even its well-equipped hospitals are feeling the strain.

After achieving a measure of control over the pandemic with broad lockdowns earlier this year, case numbers have surged since the summer and governments have ordered a second series of restrictions to limit social contacts.

In all, Europe has reported some 12.8 million cases and about 300,114 deaths. Over the past week, it has seen 280,000 cases a day, up 10% from the week earlier, representing just over half of all new infections reported globally.

Hopes have been raised by Pfizer Inc’s announcement of a potentially effective new vaccine, but it is not expected to be generally available before 2021 and health systems will have to cope with the winter months unaided.

Britain, which has imposed a fresh lockdown in England, has the highest death toll in Europe at around 49,000, and health experts have warned that with a current average of more than 20,000 cases daily, the country will exceed its “worst case” scenario of 80,000 deaths.

France, Spain, Italy and Russia have also reported hundreds of deaths a day and together, the five countries account for almost three quarters of the total fatalities.

Already facing the prospect of a wave of job losses and business failures, governments across the region have been forced to order control measures including local curfews, closing non-essential shops and restricting movement.

France, the worst-affected country in the EU, has registered more than 48,700 infections per day over the past week and the Paris region’s health authority said last week that 92% of its ICU capacity was occupied.

Facing similar pressures, Belgian and Dutch hospitals have been forced to send some severely ill patients to Germany.

In Italy, which became a global symbol of the crisis when army trucks were used to transport the dead during the early months of the pandemic, daily average new cases are at a peak at more than 32,500. Deaths have been rising by more than 320 per day over the past three weeks.

While the new vaccine being developed by Pfizer and German partner BioNTech will take time to arrive, authorities are hoping that once winter is passed, it will stem further outbreaks next year.

Citi Private Bank analysts described the news as “the first major advance toward a Post-COVID world economy”.

“More than any fiscal spending package or central bank lending program, a healthcare solution to COVID has the greatest potential to restore economic activity to its full potential…” it said in a note.

European Commission President Ursula von der Leyen on Monday said the European Union would soon sign a contract for 300 million doses of the vaccine, just hours after the drugmaker announced promising late-stage trials.

Yet health experts cautioned that the vaccine, should it be approved, was no silver bullet – not least because the genetic material it’s made from needs to be stored at temperatures of minus 70 degrees Celsius (-94 F) or below.

Such requirements pose a challenge for countries in Asia, as well as Africa and Latin America, where intense heat is often compounded by poor infrastructure.

(Reporting by Anurag Maan, Shaina Ahluwalia, Chaithra J and Roshan Abraham in Bengaluru, Sujata Rao-Coverley in London; editing by Jane Wardell, James Mackenzie, Nick Macfie and Mike Collett-White)