Tag Archives: vaccine supplies

Philippines sees 10,000 new COVID-19 cases as tight curbs return to capital

By Neil Jerome Morales

MANILA (Reuters) – The Philippines passed the 10,000 mark for new daily coronavirus infections for the first time on Monday and put its capital region back on one of its toughest levels of lockdown, to try to tackle a spike in cases that is testing its healthcare capacity.

Manila and surrounding provinces were put back under enhanced community quarantine (ECQ), the highest tier in its containment protocols, for the first time since May 2020 to try to quell the surge in cases, despite inroads late last year towards controlling its epidemic.

The country recorded 10,016 new infections on Monday, bringing the overall tally to 731,894, with deaths at 13,186, one of the highest caseloads in Asia.

Health experts say the surge in infections underscores the need to expedite a national vaccination drive, with only 656,331 healthcare workers so far given their first of two shots. The government aims to inoculate 70 million people this year.

It has also struggled to secure vaccine supplies, with an inventory of 2.525 million doses, mostly of Sinovac Biotech’s vaccine, one million of which arrived on Monday.

Philippines President Rodrigo Duterte on Monday allowed the private sector to import vaccines to boost supply and help reopen the economy.

“Whatever the cost, whatever the volume they want to bring in, it’s fine with me,” Duterte said in a national address.

Prior to Duterte’s approval, businesses go through the government for supply deals. Previously, half of the purchased doses were required to be given to the government.

Health authorities blame the spike on poor public compliance with prevention measures and the presence of new and more transmissible coronavirus variants in the capital region, which accounts for about a third of economic activity.

“This surge is really challenging while ECQ is painful, particularly for the economic sector,” said Benjamin Co, an infectious disease expert with three Manila hospitals.

The Philippines was the first country in Asia to go under a nationwide lockdown and broad restrictions and movement curbs saw its economy slump 9.5% last year, its worst economic contraction on record.

Hospitals’ intensive care and isolation bed capacity in the capital region have reached critical levels or above 70% usage, government data showed.

“I can give you beds, I can give you rooms. The problem is I cannot give you additional manpower capacity, like nurses and doctors to take care of you,” Co added.

(Reporting by Neil Jerome Morales; Editing by Ed Davies and Marguerita Choy)

COVAX vaccine program to deliver 237 million doses to 142 nations by end-May

GENEVA/LONDON (Reuters) – The COVAX vaccine-sharing program said on Tuesday it will deliver 237 million doses of AstraZeneca’s COVID-19 shot to 142 countries by the end of May as it steps up the global roll-out of its vaccine supplies.

The timeline for the delivery of doses, made by AstraZeneca and by India’s Serum Institute, will be split into separate two-month schedules, COVAX said in a statement, with the first in February-March and the second in April-May.

“These timelines are dependent on a variety of factors including national regulatory requirements, availability of supply, and fulfillment of other criteria such as validated national deployment and vaccination plans,” the statement said.

COVAX is the World Health Organization-backed program to provide vaccines for poor and middle-income countries. It began its roll-out last week with the first deliveries of shots to Ghana and Ivory Coast.

Hailing the campaign as an “unprecedented partnership,” WHO Director-General Tedros Adhanom Ghebreyesus said Angola, Cambodia, Democratic Republic of Congo and Nigeria could also expect deliveries of COVAX-supplied vaccines on Tuesday.

“This is an unprecedented partnership that will not only change the course of the pandemic but also change the way the world responds to future health emergencies,” Tedros told a joint media briefing with the U.N. Children’s Fund UNICEF, the GAVI vaccines alliance – which co-leads COVAX – and others.

Ghanaian President Nana Akufo-Addo told the same briefing that his West African country, which this week began its inoculation campaign with COVAX doses, aimed to vaccinate 20 million people by the end of 2021.

COVAX added in a statement that as well as the first round of allocations of the AstraZeneca vaccine, some 1.2 million doses of the Pfizer-BioNTech COVID shot were also anticipated for delivery in the first quarter of 2021.

(Reporting by Emma Farge and Stephanie Nebehay in Geneva and Kate Kelland in London; Editing by Mark Heinrich)

Exclusive: UK auditing Indian vaccine site amid scramble for shots-sources

By Neha Arora, Krishna N. Das and Euan Rocha

NEW DELHI (Reuters) – Britain’s drug regulator is auditing manufacturing processes at Serum Institute of India (SII) which could pave the way for AstraZeneca’s COVID-19 vaccine to be shipped from there to the UK and other countries, according to two sources close to the matter.

SII, the world’s largest vaccine manufacturer, is currently mass producing the AstraZeneca vaccine, developed in conjunction with Oxford University, for dozens of poor and middle-income countries but not the UK, which has been getting its supply of the shot primarily from domestic facilities.

If the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) gives SII’s manufacturing process for the Oxford/AstraZeneca shot a greenlight it would allow the drug to be exported to the UK and to other countries which recognize MHRA’s clearances, one of the sources said.

Reuters could not determine what was the rationale for the audit. SII did not respond to a request for comment on it. The MHRA confirmed that an inspection was happening but declined further comment.

“Due to commercial confidentiality we do not comment on inspections that are still ongoing,” the regulator’s chief executive Dr. June Raine said in a statement to Reuters.

The two sources, who asked not to be named as the matter is private, said the audit should be relatively routine for SII, as its site already supplies other vaccines to the UK.

The inspection comes as countries around the world scramble to secure vaccine supplies amid supply disruptions and delivery cuts from leading drugmakers such as Pfizer Inc, Moderna and AstraZeneca.

It was not immediately clear whether an MHRA approval would allow the UK or AstraZeneca to route SII volumes of COVISHIELD – the brand name under which SII markets the AstraZeneca shot – to the EU, which has been pressuring the UK for supply from AstraZeneca’s facilities in the UK, amid shortages in Europe.

AstraZeneca executives told EU officials last week that to accelerate supplies to the bloc, it could provide it with some doses manufactured outside Europe, two EU sources told Reuters. One said the SII could be a supplier.

AstraZeneca, which has previously tapped SII to help fulfill some of its vaccine orders from Brazil, South Africa and Saudi Arabia, did not respond to a request for comment on whether it needs SII to help meet commitments in the UK, or in any other nations that would recognize an MHRA certification.

It was not immediately available to comment on the reported offer to supply the EU with shots from the SII.

INSPECTIONS

The EU’s drug regulator, the European Medicines Agency (EMA), audits sites from which it plans to source medicines but during the global pandemic, with multiple COVID-19 vaccines being developed, it is also partly leaning on inspections carried out by some other international regulators.

“Inspection outcomes for Covid-19 vaccines conducted by the MHRA will be considered by EMA,” said the regulator. Any such approved sites would also need an EMA sign off before they can export to the EU, the regulator told Reuters.

MHRA declined to comment on specifics, but Raine said it was collaborating “with international partners in response to the global pandemic and on matters of mutual interest.”

The UK has expressed an interest in purchasing vaccines from SII, according to the second source, along with a government official in New Delhi. The two sources said the volumes or timelines for any such purchases were unclear.

A UK government spokeswoman said: “Any discussions that have taken place between the UK Government and India on vaccines are not related to securing extra vaccine supply to the UK.”

The UK has so far ordered 100 million doses of AstraZeneca’s vaccine.

“Most countries have approached us and India’s government,” SII told Reuters, but it did not comment on any UK outreach. “We are trying our best to meet demand, and supply the vaccine to as many countries as possible, keeping India as the priority.”

SII’s chief executive, Adar Poonawalla, told Reuters in late January, his family-owned firm was keen to support AstraZeneca’s supply needs but its primary focus was on India and other poorer nations in Asia and Africa. He said at the time SII had no plans to divert supplies to Europe.

(Neha Arora and Krishna N.Das reported from New Delhi and Euan Rocha reported from Mumbai; Additional reporting by Paul Sandle, Kate Kelland and Alistair Smout in London, Francesco Guarascio in Brussels and Ludwig Burger in Frankfurt; Editing by Carmel Crimmins)