Spain’s rising COVID-19 rate gathers pace

MADRID (Reuters) – Spain’s coronavirus infection rate rose by more than 10 since Friday, with 15,500 cases added to the tally, Health Ministry data showed on Monday, as a gradual uptick in contagion from mid-March lows gathered pace.

The rate, which is measured over the preceding 14 days, rose to 149 cases per 100,000 people from 138 cases on Friday, the data showed.

It had been inching higher since dropping below 130 cases per 100,000 people in mid-March and remains well below the peak of nearly 900 cases recorded in late January.

Monday’s infection numbers brought the total since the start of the pandemic to 3.27 million cases. The death toll climbed by 189 since Friday to 75,199.

“At a national level we are in a phase of expansion” of new cases, Health Emergency Chief Fernando Simon told a news conference, adding that the trend was likely to continue in the coming days.

Though bars and restaurants remain open in much of the country, Spain has banned travel between different regions and limited social events to four people during Holy Week to prevent Easter celebrations triggering a fresh resurgence in contagion.

“If we manage to follow the Easter restrictions, we may not be talking about a fourth wave,” Simon said.

(Reporting by Nathan Allen; editing by Jonathan Oatis)

Spain close to vaccinating all nursing-home residents, on track for summer goals

By Nathan Allen

MADRID (Reuters) – Spain has given a full two-shot course of coronavirus vaccines to almost all its elderly nursing-home residents, the FED care-home association said on Friday, restoring some sense of security to the most vulnerable section of the population.

Separately, Prime Minister Pedro Sanchez said the country, which has administered 2.8 million doses and fully inoculated 1.14 million people, was on track to vaccinate 20 million people in the first half of 2021 out of a population of 47 million.

Nearly 43,000 care-home residents died of COVID-19 or suspected infection in the devastating March-May first wave of contagion, and prosecutors are investigating more than 200 cases of potential criminal negligence at such homes.

But more than 97% of residents have now been vaccinated across Spain’s 17 regions, according to the FED, putting nursing homes among the country’s safest places.

“They are very positive data that allow us to be optimistic about the future,” said FED’s president Ignacio Fernandez Cid. “Immunity will allow us to gradually return to the longed-for lost normality.”

Health Emergency Chief Fernando Simon said earlier this week that for the first time since the start of the pandemic, people over 65 who live in care homes have a lower rate of infection than those who live outside, supporting the thesis, if indirectly, that the vaccines are having an effect.

Frontline medics and care workers are the only people under 65 to receive a vaccine so far.

Spain will now give shots made by Pfizer-BioNTech and Moderna to people over 80, while AstraZeneca’s drug will go to key workers under 55.

With a third wave quickly receding, Spain’s two-week infection rate hit 321 cases per 100,000 people on Thursday, from almost 900 cases at the end of January, prompting several regions to relax measures.

Madrid on Thursday pushed its curfew back an hour to 11 p.m. and on Friday lifted travel restrictions on 31 neighborhoods.

(Reporting by Nathan Allen, editing by Andrei Khalip)

Spain opens 200 criminal probes into care home pandemic failings

MADRID (Reuters) – Spain’s public prosecutor is investigating more than 200 cases of potential criminal mishandling of the coronavirus pandemic at nursing homes, where the virus spread almost unchecked during the devastating first wave.

Nearly 43,000 care home residents died of COVID-19 or suspected infection during the March-May first wave of contagion, according to official data.

At the time, staff reported shortages of basic protective equipment and army units deployed on disinfection missions discovered unattended bodies at several facilities.

The prosecutor’s office said nearly half of its investigations related to homicide through a neglect of duty of care, while it was looking into 21 cases of deficiencies in medical treatment.

With Spain reporting record infection numbers on an almost daily basis, it warned that risks still remained across the care home network, despite improvements made in recent months.

“The increase in general contagion is still a risk for residential environments,” it said in a statement on Thursday, adding that it would continue to closely monitor the situation.

Pre-existing weaknesses, including governance, funding, working conditions, a lack of coordination with primary health care, and a lack of isolation spaces, are still widespread, the report said.

Prosecutors shelved other cases, most of the time after charges were rolled into other cases or passed to courts, rather than because investigators found no evidence of wrongdoing.

Spain has about 5,500 nursing homes, housing some 400,000 people, according to the European Ageing Network, which represents both individual carers and businesses.

The heads of both Spain’s main care home associations said they needed more information on the investigations before commenting. In the past, the associations have blamed the government for failing to provide adequate supplies and the health service for refusing to admit residents with a positive diagnosis to hospitals.

(Reporting by Nathan Allen, Belén Carreño, Emma Pinedoñ; Editing by Ingrid Melander and Andrew Cawthorne)

Spain’s COVID-19 incidence hits new high as third wave of infection rages

MADRID (Reuters) – Spain’s incidence of the coronavirus as measured over the past 14 days reached a new high of 714 cases per 100,000 people on Tuesday after 689 cases the previous day, Health Ministry data showed, as a rampant third wave of infection grips the country.

The ministry reported 34,291 new infections, retreating from Friday’s record rise of more than 40,000, and bringing the cumulative tally to 2,370,742.

Spain’s overall death toll from the virus rose by 404 to 54,173, the data showed. Although daily increases in the death toll have been on the rise, it is still far below the nearly 900 deaths registered per day in late March and early April.

(Reporting by Nathan Allen, editing by Andrei Khalip)

Europe COVID death toll tops 300,000 as winter looms and infections surge

By Shaina Ahluwalia, Anurag Maan and Roshan Abraham

(Reuters) – More than 300,000 people have died of COVID-19 across Europe, according to a Reuters tally on Tuesday, and authorities fear that fatalities and infections will continue to rise as the region heads into winter despite hopes for a new vaccine.

With just 10% of the world’s population, Europe accounts for almost a quarter of the 1.2 million deaths globally, and even its well-equipped hospitals are feeling the strain.

After achieving a measure of control over the pandemic with broad lockdowns earlier this year, case numbers have surged since the summer and governments have ordered a second series of restrictions to limit social contacts.

In all, Europe has reported some 12.8 million cases and about 300,114 deaths. Over the past week, it has seen 280,000 cases a day, up 10% from the week earlier, representing just over half of all new infections reported globally.

Hopes have been raised by Pfizer Inc’s announcement of a potentially effective new vaccine, but it is not expected to be generally available before 2021 and health systems will have to cope with the winter months unaided.

Britain, which has imposed a fresh lockdown in England, has the highest death toll in Europe at around 49,000, and health experts have warned that with a current average of more than 20,000 cases daily, the country will exceed its “worst case” scenario of 80,000 deaths.

France, Spain, Italy and Russia have also reported hundreds of deaths a day and together, the five countries account for almost three quarters of the total fatalities.

Already facing the prospect of a wave of job losses and business failures, governments across the region have been forced to order control measures including local curfews, closing non-essential shops and restricting movement.

France, the worst-affected country in the EU, has registered more than 48,700 infections per day over the past week and the Paris region’s health authority said last week that 92% of its ICU capacity was occupied.

Facing similar pressures, Belgian and Dutch hospitals have been forced to send some severely ill patients to Germany.

In Italy, which became a global symbol of the crisis when army trucks were used to transport the dead during the early months of the pandemic, daily average new cases are at a peak at more than 32,500. Deaths have been rising by more than 320 per day over the past three weeks.

While the new vaccine being developed by Pfizer and German partner BioNTech will take time to arrive, authorities are hoping that once winter is passed, it will stem further outbreaks next year.

Citi Private Bank analysts described the news as “the first major advance toward a Post-COVID world economy”.

“More than any fiscal spending package or central bank lending program, a healthcare solution to COVID has the greatest potential to restore economic activity to its full potential…” it said in a note.

European Commission President Ursula von der Leyen on Monday said the European Union would soon sign a contract for 300 million doses of the vaccine, just hours after the drugmaker announced promising late-stage trials.

Yet health experts cautioned that the vaccine, should it be approved, was no silver bullet – not least because the genetic material it’s made from needs to be stored at temperatures of minus 70 degrees Celsius (-94 F) or below.

Such requirements pose a challenge for countries in Asia, as well as Africa and Latin America, where intense heat is often compounded by poor infrastructure.

(Reporting by Anurag Maan, Shaina Ahluwalia, Chaithra J and Roshan Abraham in Bengaluru, Sujata Rao-Coverley in London; editing by Jane Wardell, James Mackenzie, Nick Macfie and Mike Collett-White)

No clear link between school opening and COVID surge, study finds

By Kate Kelland

LONDON (Reuters) – Widespread reopening of schools after lockdowns and vacations is generally not linked to rising COVID-19 rates, a study of 191 countries has found, but lockdown closures will leave a 2020 “pandemic learning debt” of 300 billion missed school days.

The analysis, by the Zurich-based independent educational foundation Insights for Education, said 84% of those 300 billion days would be lost by children in poorer countries, and warned that 711 million pupils were still out of school.

“It’s been assumed that opening schools will drive infections, and that closing schools will reduce transmission, but the reality is much more complex,” said IfE’s founder and chief executive Randa Grob-Zakhary.

The vast majority – 92% – of countries that are through their first wave of COVID-19 infections have started to reopen school systems, even as some are seeing a second surge.

IfE found that 52 countries that sent students back to school in August and September – including France and Spain – saw infection rates rise during the vacation compared to when they were closed.

In Britain and Hungary, however, infection levels dropped after initial school closures, remained low during the holidays, and began rising after reopening.

Full analysis of these 52 countries found no firm correlation between school status and infections – pointing to a need to consider other factors, IfE said.

“The key now is to learn from those countries that are reopening effectively against a backdrop of rising infections,” Grob-Zakhary said.

The report said 44 countries have kept schools closed.

It found countries are developing strategies for schools during the pandemic – including some, such as Italy, France, which order temporary school closures on a case-by-case basis.

Other measures include policies on masks, class rotations and combining remote with in-school lessons.

“This first real global test highlights what school life looks like in a COVID-world,” said Grob-Zakhary. “Understanding how countries undergoing a massive second wave are dealing with this new reality in the classroom is essential to guide future reopening decisions and to help schools remain open.”

(Reporting by Kate Kelland; Editing by Giles Elgood)

Spain sentences Salvadoran ex-officer to 133 years in jail over priests’ massacre

MADRID (Reuters) – Spain’s High Court sentenced a former army colonel from El Salvador on Friday to 133 years in prison for the murder of five Spanish Jesuit priests in 1989 during the Central American country’s civil war.

Inocente Orlando Montano Morales, 77, was also found responsible by the judges for the murders of the priests’ housekeeper and her 15-year-old daughter, as well as a local Jesuit priest. The court could not convict him of these crimes because his extradition to Spain did not cover these cases.

The massacre was one of the most notorious acts of a decade-long civil war during which 75,000 people were killed and 8,000 went missing.

The judges said they found Montano Morales guilty of five counts of “murder of terrorist nature,” adding that the killings were committed by the state apparatus, making them what “is commonly known as terrorism implemented by the state”.

They added that the total maximum prison term is 30 years.

Montano Morales has been in custody since 2011 when he was arrested in the United States on immigration fraud charges. He was deported to Spain in 2017.

The Spanish government has indicted 20 former Salvadoran army officers for the killings of the priests, their housekeeper and her daughter. One of the priests, Father Ignacio Ellacuria, was a prominent critic of the U.S.-backed right-wing government.

The massacre occurred on Nov. 16, 1989, when a group of soldiers from the U.S.-trained Atlacatl Battalion entered the campus of the Central American University where Ellacuria was rector.

Ellacuria had advocated a negotiated settlement to the military-led junta government’s war against the left-wing Farabundo Marti National Liberation Front (FMLN). International revulsion at the murders of the priests helped to push through such a solution, with the war ending in 1992.

(Reporting by Nathan Allen and Andrei Khalip; Editing by Ingrid Melander and Frances Kerry)

Swiss add Paris, Vienna to list of areas for coronavirus quarantine

ZURICH (Reuters) – Switzerland has added the regions around Paris and Vienna to its list of areas with high COVID-19 infection rates requiring incoming travelers to enter quarantine for 10 days.

The government said it was adopting a regional approach for neighboring countries for the measures which will come into force on Sept. 14. As part of this, it named Ile de France and the Vienna region as areas with a raised risk of infection.

The government also put the Czech Republic and all of Spain on its list of entire countries with a quarantine requirement, which already includes the United States,  India and Brazil.

“It is not a good idea to go to high-risk areas,” Health Minister Alain Berset told a media conference, advising Swiss travelers to steer clear of places on the list.

Switzerland, which has had quarantine restrictions since July 6, said it was responding to a spike in infection numbers in the country.

Switzerland reported 528 new cases of the coronavirus on Friday, the highest daily rise in infections since early April.

As part of its new approach, the government said only regions of neighboring countries where the infection rate is above its limit of 60 cases per 100,000 people will be added to the list, rather then the entire country.

Border regions may be exempted from the list to take into account the close interaction with neighboring regions, it said.

Thousands of workers cross Switzerland’s borders with France, Germany and Italy daily to work in Geneva, Basel and the southern canton of Ticino.

(Reporting by John Revill; Editing by Michael Shields)

Steroids cut death rates among critically ill COVID-19 patients, major study finds

By Kate Kelland

LONDON (Reuters) – Treating critically ill COVID-19 patients with corticosteroid drugs reduces the risk of death by 20%, an analysis of seven international trials found on Wednesday, prompting the World Health Organisation to update its advice on treatment.

The analysis – which pooled data from separate trials of low dose hydrocortisone, dexamethasone and methylprednisolone – found that steroids improve survival rates of COVID-19 patients sick enough to be in intensive care in hospital.

“This is equivalent to around 68% of (the sickest COVID-19) patients surviving after treatment with corticosteroids, compared to around 60% surviving in the absence of corticosteroids,” the researchers said in a statement.

The WHO’s clinical care lead, Janet Diaz, said the agency had updated its advice to include a “strong recommendation” for use of steroids in patients with severe and critical COVID-19.

“The evidence shows that if you give corticosteroids …(there are) 87 fewer deaths per 1,000 patients,” she told a WHO social media live event. “Those are lives … saved.”

“Steroids are a cheap and readily available medication, and our analysis has confirmed that they are effective in reducing deaths amongst the people most severely affected by COVID-19,” Jonathan Sterne, a professor of medical statistics and epidemiology at Britain’s Bristol University who worked on the analysis, told the briefing.

He said the trials – conducted by researchers in Britain, Brazil, Canada, China, France, Spain, and the United States – gave a consistent message throughout, showing the drugs were beneficial in the sickest patients regardless of age or sex or how long patients had been ill.

The findings, published in the Journal of the American Medical Association, reinforce results that were hailed as a major breakthrough and announced in June, when dexamethasone became the first drug shown to be able to reduce death rates among severely sick COVID-19 patients.

Dexamethasone has been in widespread use in intensive care wards treating COVID-19 patients in some countries since then.

Martin Landray, a professor of medicine and epidemiology at the University of Oxford who worked on the dexamethasone trial that was a key part of the pooled analysis published on Wednesday, said the results mean doctors in hospitals across the world can safely switch to using the drugs to save lives.

CLEAR BENEFITS

“These results are clear, and instantly usable in clinical practice,” he told reporters. “Among critically ill patients with COVID-19, low-dose corticosteroids … significantly reduce the risk of death.”

Researchers said the benefit was shown regardless of whether patients were on ventilation at the time they started treatment. They said the WHO would update its guidelines immediately to reflect the fresh results.

Until the June findings on dexamethasone, no effective treatment had been shown to reduce death rates in patients with COVID-19, the respiratory disease caused by the new coronavirus.

More than 25 million people have been infected with COVID-19 and 856,876​ have died, according to a Reuters tally.

Gilead Sciences Inc’s remdesivir was authorized by United States regulators in May for use in patients with severe COVID-19 after trial data showed the antiviral drug helped shorten hospital recovery time.

Anthony Gordon, an Imperial College London professor who also worked on the analysis, said its results were good news for patients who become critically ill with COVID-19, but would not be enough to end outbreaks or ease infection control measures.

“Impressive as these results are, this is not a cure. We now have something that will help, but it is not a cure, so it’s vital that we keep up all the prevention strategies.”

(Reporting by Kate Kelland; Editing by Mark Heinrich and Catherine Evans)

J&J to start mid-stage coronavirus vaccine trials in three European countries

By Nathan Allen

MADRID (Reuters) – Johnson & Johnson’s Janssen unit will begin mid-stage trials for its coronavirus vaccine in Spain, the Netherlands and Germany next week, Spain’s health minister said on Friday, as the U.S. drugmaker expands testing for its experimental shot.

The Phase II trial will last two months and include 550 participants across the three countries, including 190 people in Spain, Salvador Illa told a news conference in Madrid.

“It’s a vote of confidence in our health system,” Illa said, adding it was the first human trial for a coronavirus vaccine to be approved in Spain.

The study will focus on healthy people between the ages of 18 and 55 as well as people over 65.

Johnson & Johnson said the study will evaluate the safety and the ability to induce an immune response from single dose and two-dose regimens of the vaccine candidate, the company said in a statement.

Spain, which has western Europe’s highest tally of coronavirus cases, is also working with AstraZeneca via the European Union’s vaccine procurement program to secure sufficient doses.

J&J’s website says if the latest trials are successful, it will begin final Phase III studies, in which even more volunteers will receive the experimental vaccine.

More than 150 potential vaccines are being developed and tested globally to combat the COVID-19 pandemic, with 30 in human trials.

There is so far no approved vaccine, except one authorized in Russia before large-scale trials.

J&J is carrying out tests in the United States and Belgium, and this week added Chile, Argentina and Peru to the list of Latin American nations where it plans to conduct Phase III trials on 60,000 volunteers, in a study that will also cover Brazil, Colombia and Mexico.

The company’s potential vaccine uses “viral vectors” to generate immune responses, similar to the approach taken by the University of Oxford and AstraZeneca in their experimental vaccine, as well as China’s CanSino.

(Reporting by Nathan Allen and Jose Elías Rodríguez; editing by Mark Potter and Jason Neely)