Floridians return to shattered homes as Irma crosses into Georgia

Residents walk through flood waters left in the wake of Hurricane Irma in a suburb of Orlando, Florida, U.S., September 11, 2017. REUTERS/Gregg Newton

By Andy Sullivan and Robin Respaut

FLORIDA CITY/MARCO ISLAND, Fla. (Reuters) – Shocked Florida residents returned to their shattered homes on Monday as the weakened Hurricane Irma pushed inland, flooding cities in the northeastern part of the state and leaving millions without power.

Downgraded to a tropical storm early on Monday, Irma had ranked as one of the most powerful Atlantic hurricanes recorded. It cut power to millions of people and ripped roofs off homes as it hit a wide swath of Florida on Sunday and Monday and moved into neighboring states.

Authorities said the storm had killed 39 people in the Caribbean and one in Florida, a man found dead in a pickup truck that had crashed into a tree in high winds on the Florida Keys over the weekend.

With sustained winds of up to 60 mph (100 kph), Irma had crossed into Georgia and was located about 47 miles (76 km)northeast of the Florida state capital Tallahassee, the National Hurricane Center said at 2 p.m. ET.

In Miami’s Little Haiti neighborhood, people returned to the wreckage of trailers shredded by the storm after the city escaped the worst of Irma’s winds but experienced heavy flooding.

Melida Hernandez, 67, who had ridden out the storm at a nearby church, found her home split down the middle by a tree.

“I wanted to cry, but this is what it is, this is life,” Hernandez said.

High winds snapped power lines and left about 7.3 million homes and businesses without power in Florida and elsewhere in the U.S. Southeast, state officials and utilities said. They said it could take weeks to complete repairs.

Miami International Airport, one of the busiest in the country, halted passenger flights through at least Monday.

Police in Miami-Dade County said they had made 29 arrests for looting and burglary. Fort Lauderdale police said they had arrested 19 people for looting.

Some residents who had evacuated the Florida Keys archipelago, where Irma roared ashore on Sunday with winds up to 130 mph (209 kph), grew angry as they tried to return to their homes on Monday.

A few dozen people argued with police who turned them away from the first of a series of bridges leading to the island chain, which officials warned still lacked power, water and cellphone service.

White House homeland security adviser Tom Bossert said it might be weeks before many residents of the Keys were able to return. “The Keys are going to take a while,” Bossert told a regular White House briefing. “I would expect that the Keys are not fit for re-entry for regular citizenry for weeks.”

Irma hit Florida after powering through the Caribbean as a rare Category 5 hurricane. It killed 39 people there, including 10 in Cuba, which was battered over the weekend by ferocious winds and 36-foot (11-meter) waves.

A week earlier Hurricane Harvey flooded a wide swath of Houston. Nearly three months remain in the official Atlantic hurricane season.

Northeastern Florida cities including Jacksonville were flooding on Monday, with police pulling residents from waist-deep water.

“Stay inside. Go up. Not out,” Jacksonville’s website warned residents. “There is flooding throughout the city.”

The city also warned residents to be wary of snakes and alligators driven into the floodwater.

 

BILLIONS IN DAMAGE

The storm did some $20 billion to $40 billion in damage to insured property as it tore through Florida, catastrophe modeling firm AIR Worldwide estimated.

That estimate, lower than earlier forecasts of up to $50 billion in insured losses, helped spur a relief rally on Wall Street as fears eased that Irma would cut into U.S. economic growth.

Shares of insurance companies were among the big winners, with Florida-based Federated National, HCI Group and Universal Insurance all up more than 12 percent.

Some 6.5 million people, about one-third of Florida’s population, had been ordered to evacuate their homes ahead of Irma’s arrival. More than 200,000 people sought refuge in about 700 shelters, according to state data.

As shelters began to empty on Monday, some 7,000 people filed out of Germain Arena in Estero, south of Fort Myers. The crowd included Don Sciarretta, who rode out the storm with his 90-year-old friend, Elsie Johnston, who suffers from Alzheimer’s disease.

Sciarretta, 73, spent two days without sleep, holding up a slumped-over Johnston and making sure she did not fall out of her chair. He relied on other people in the shelter to bring the pair food, often after waiting in hours-long lines.

“For the next storm, I’ll go somewhere on my own like a hotel or a friend’s house,” Sciarretta said. “I’m not going through this again.”

Shelters across western Florida opened, filled up – and often closed because of overcrowding – after the storm made a western shift on Saturday.

U.S. President Donald Trump, attending a ceremony at the Pentagon on the 16th anniversary of the Sept. 11 attacks, vowed a full response to Irma as well as ongoing federal support for victims of Hurricane Harvey, which flooded Texas.

“These are storms of catastrophic severity and we are marshalling the full resources of the federal government to help our fellow Americans,” Trump said.

On Marco Island, where the storm made its second landfall on Sunday, residents were cleaning up damaged homes and dealing with the downed trees that knocked out power lines and crushed cars.

Salvatore Carvelli, Jr., 45, rode out the storm in DaVinci’s, his Italian restaurant.

“It sounded like a train going through,” Carvelli said.

The winds tore the air conditioner from his restaurant’s roof, he said, adding that the storm surge added to the danger.

“There was no road that you could see,” Carvelli said. “The parking lot was gone, you could fish.”

 

(Additional reporting by Daniel Trotta in Orlando, Bernie Woodall, Ben Gruber and Zachary Fagenson in Miami, Letitia Stein in Detroit, Colleen Jenkins in Winston-Salem, N.C., Doina Chiacu and Jeff Mason in Washington, Scott DiSavino in New York and Marc Frank in Havana; Writing by Scott Malone; Editing by Frances Kerry, Howard Goller and Paul Sim

Spiders, snakes and scorpions join fight against superbugs

By Matthew Stock

(Reuters) – A British lab is searching for new medicines in the poisonous secretions of some of the world’s deadliest creatures, addressing the increasingly desperate challenge of finding viable new drugs.

Over-prescription and over-use in farming of antibiotics has given rise to so-called ‘superbugs’, multi-drug resistant infections that can evade even the medicines designed to kill them. Experts have warned since the 1990s that lethal super-bugs were on the horizon, but few drug makers have attempted to develop drugs against them.

Venomtech, based in south-east England, believe help could be found in the unlikeliest of sources; the venom of spiders, scorpions and snakes that is often fatal to humans. Millions of years of evolution has given these creature’s venom the ability to target and attack their prey while avoiding the body’s defenses. Venomtech scientists hope that an injected drug could perform the same function.

When broken down at the molecular level a tiny droplet of venom contains hundreds of individual components that could eventually be made into new drugs, explained Venomtech founder Steven Trim.

“The principle of Venomtech is separating venoms out into their component parts and targeting them to the right disease area,” Trim told Reuters.

He added that his drug discovery team was “putting the right venom for the right drug target so we maximize the hits – and a hit is an interesting peptide that might make it to a drug.”

Around 400 animals are kept at his lab in Kent, including about 70 species of tarantula and 30 species of scorpion. Many of these kill their prey with venoms that contain hundreds of protein molecules, some of which block nerve activity. Venomtech keep a number of invertebrates which can be deadly to humans, namely the black widow spider and deathstalker scorpion.

Trim, who worked for pharmaceutical company Pfizer before founding Venomtech, stressed that the venom extraction process causes no discernible harm to the creatures.

“We anesthetize the invertebrates, just to temporarily put them to sleep, it makes it safer for us because if they’re immobile they can’t bite us. But also it’s better for the animals as well. And using a very tiny electrical stimulation, just to contract the muscle and squeeze the gland we get a small amount of venom produced,” he said.

The venom extracted from each creature can be measured in micro-liters; a thousandth of a milliliter. Nevertheless, this tiny volume holds hundreds of useful molecules.

“The average scorpion will only produce 2 or 3 micro-liters. So it’s a really small amount. But in that small amount there’s a lot of interesting peptides; several hundred different components and several micro-grams of protein in there, so there’s plenty for us to work with,” Trim said. “We separate that out in a two phase process called high pressure liquid chromatography. And that gives us typically about a hundred fractions per venom, and each one of those fractions may contain 1 to 5 individual peptides. And it’s those individual peptides and proteins that are the real interesting things; these are the molecules that convey the biological activity of the venom.”

Working with scientists from nearby Canterbury Christ Church University, they’ve been screening their venom-derived ‘chemical library’ against different diseases.

Trim said they’ve had some extremely encouraging results.

“Some of them we found can kill bacteria, bacteria like E.Coli and Staphylococcus, so very relevant at the moment where modern medicines are failing. And we’re also finding venoms that are modifying and killing cancer cells,” he said, adding that Venomtech is now working with pharmaceutical companies to turn their venom discoveries into the next generation of drugs.