India AstraZeneca shot delay could be ‘catastrophic’ for Africa: health official

ADDIS ABABA (Reuters) – India’s temporary hold on major exports of AstraZeneca’s COVID-19 shot will undermine Africa’s vaccination plans, and could have a “catastrophic” impact if extended, the head of the continent’s disease control body said on Thursday.

India decided to delay big exports of the shots made in its territory by the Serum Institute of India (SII) to make sure it could meet local demand, two sources told Reuters last week.

The hold “will definitely impact our ability to continuously vaccinate people,” the director of the Africa Centers for Disease Control and Prevention, John Nkengasong, told a news conference in Addis Ababa.

The African Union had planned to vaccinate 30-35% of the continent’s population by the end of the year he said. “If the vaccines are delayed we are unlikely to meet our target,” he added.

That AU target primarily relies on supplies from the global COVAX vaccine-sharing facility, through which 64 poorer countries including many in Africa are supposed to get doses from the SII. COVAX aims to provide enough shots for African countries to inoculate at least 20% of their populations.

“If the delay continues, I hope it’s a delay and not a ban, that would be catastrophic for meeting our vaccinations schedule,” Nkengasong said.

African countries have reported 4.25 million coronavirus infections and 112,000 related deaths, though experts have said the actual numbers could be higher.

The AU has also been negotiating with manufacturers to help member states secure the additional doses they will need to achieve 60% coverage.

On Monday, Johnson & Johnson announced it would supply the AU with up to 400 million doses of its COVID-19 vaccine. Delivery of those doses is due to begin in the third quarter of this year and will continue through 2022.

Those doses are separate from the GAVI/WHO-backed global COVAX facility.

Nkengasong said on Thursday the AU has “pivoted” towards the J&J shot in part as a result of the delay in the delivery of AstraZeneca shots, and also because it is a single-dose shot.

The J&J doses will begin to arrive in June or July, which will ease any shortage caused by the delay in the AstraZeneca doses, Nkengasong said. The gap until the arrival of the J&J doses is a concern, he added.

(Reporting by Addis Ababa newsroom; Writing by Maggie Fick; Editing by Andrew Heavens)

‘Falling like flies’: Hungary’s Roma community pleads for COVID help

By Marton Dunai

BUDAPEST (Reuters) – Coronavirus infections are ravaging Hungary’s 700,000-strong Roma community, according to personal accounts that suggest multiple deaths in single families are common in an unchecked outbreak fueled by deep distrust of authorities.

Data on infections in the community is unavailable but interviews with about a dozen Roma, who often live in cramped and unsanitary conditions, reveal harrowing stories of suffering and death and of huge health-care challenges.

“Our people are falling like flies,” said Aladar Horvath, a Roma rights advocate who travels widely among the community.

When asked by phone to describe the overall situation, he broke down sobbing and said he had learned an hour before that his 35-year-old nephew had died of COVID.

Another Roma, Zsanett Bito-Balogh, likened the outbreak in her town of Nagykallo in eastern Hungary to an explosion.

“It’s like a bomb went off,” she said.

“Just about every family got it…People you see riding their bikes one week are in hospital the next and you order flowers for their funerals the third.”

Bito-Balogh, who herself recovered twice from COVID-19, said that at one point she had 12 family members in hospital. She said she had lost two uncles and her grandmother to the virus in the past month, and a neighbor lost both parents, a cousin and a uncle within weeks.

She says she is now rushing to organize in-person registration points for vaccines and plans to have the network up and running in a few weeks.

Despite the challenges in persuading many Roma to turn to health authorities for medical care and vaccinations, Roma leaders are urging the government to do more to intervene and tackle what Horvath describes as a humanitarian crisis.

Prime Minister Viktor Orban’s chief of staff, Gergely Gulyas, said vaccinations would be rolled out to Roma but that the community needed to volunteer for their shots.

“Once we get to that point, the younger Roma should get in line,” Gulyas said in answer to Reuters questions. The Roma community is predominantly young, which means their vaccinations are scheduled later than for older Hungarians.

The government’s chief epidemiologist did not respond to requests for comment.

DECADES OF MISTRUST

Barely 9% of Roma want to be vaccinated against COVID-19, according to a survey carried out at Hungary’s University of Pecs in January but published here for the first time. It was conducted by Zsuzsanna Kiss, a Roma biologist and professor at Hungary’s University of Pecs.

Kiss said the Roma have mistrusted doctors and governments for decades because of perceived discrimination.

However, gaining Roma trust is not the only challenge.

Hungary’s 6,500 general practitioners are leading the vaccine roll-out, but 10% of small GP clinics are shut because there is no doctor to operate them, mostly in areas with high Roma populations, government data shows.

Although the government has deployed five “vaccination buses” that tour remote areas, people must first register for inoculations.

“The rise in cases (among the Roma) is clearly proportionate to vaccine rejection,” said former Surgeon General Ferenc Falus.

“This more infectious virus reaches a population whose immune system has weakened greatly during the winter months. If they go without vaccines for long, it will definitely show in extra infections and fatalities among the Roma.”

Hungary currently has the world’s highest weekly per capita death toll, driven by the more contagious variant first detected in Britain, despite a rapid vaccination rollout, data from Johns Hopkins University and the European Union indicates.

“We never trusted vaccines much,” said Zoltan Varga, a young Roma also from Nagykallo.

(Reporting by Marton Dunai; Editing by Mark Bendeich and Mark Heinrich)

COVID-19 third leading cause of U.S. deaths in 2020 after heart disease, cancer: U.S. report

By Vishwadha Chander

(Reuters) – COVID-19 was the primary or contributing cause of 377,883 deaths in the United States last year, with a particularly high toll among the elderly, according to a government report released on Wednesday.

The COVID-19 mortality rate made it the third leading cause of death in the United States in 2020 after heart disease and cancer, the U.S. Centers for Disease Control and Prevention (CDC) analysis found.

The CDC said that the overall U.S. mortality rate increased for the first time since 2017, by nearly 16%, to 3,358,814 deaths. The jump was driven by COVID-19, which accounted for an increase of 11.3%.

The overall death rate was lowest among children aged 5 to 14 years, and highest among people over age 85, the report found. A total of 134 children aged 14 and under died from COVID-19 in 2020, while 120,648 people aged 85 and older died from the disease. People 75-84 years old accounted for 104,212 deaths.

The COVID-19 death rate was highest among Hispanics, followed by Black non-Hispanics, the CDC’s analysis found. A total of 68,469 Hispanics died from COVID-19 and 59,871 non-Hispanic Black people died. It said 228,328 White non-Hispanics died.

The CDC report is based on death certificate data between January and December 2020.

Provisional estimates from the CDC, published last month, showed that life expectancy in the U.S. fell by a year in the first half of 2020 – the biggest decline since World War 2 – and stood at the lowest levels since 2006.

The CDC’s current analysis is based on provisional death estimates, but they provide an early indication of shifts in mortality trends, the agency said.

The CDC pointed out that limited availability of testing for the coronavirus at the beginning of the pandemic might have resulted in an underestimation of COVID-19–associated deaths.

(Reporting by Reporting by Vishwadha Chander and Caroline Humer; Editing by Bill Berkrot)

U.S. COVID-19 cases top 30 million as states race to vaccinate

By Anurag Maan

(Reuters) – The United States crossed 30 million coronavirus cases on Wednesday, according to a Reuters tally, as states accelerate the vaccination process by lowering age limits.

Health authorities are racing to vaccinate in the face of the first uptick in new cases on a weekly basis since January. Against the advice of health experts, several states have lifted mask mandates and more infectious variants have also spread across the nation.

Although cases are trending higher in 30 out of 50 states compared with the previous week, health officials hope the vaccinations will prevent a rise in deaths. The United States has lost a total of 544,000 lives to the virus.

New York on Monday joined Florida and a handful of other states that have made vaccines available to people who are at least 50 years old.

In the past two weeks, many states including Alaska, Arizona and Texas have lowered down their eligibility age for coronavirus vaccines.

Arizona lowered the eligibility age to 16 at state-run vaccination sites in three populous southern counties, effective Wednesday. Three other counties already have eligibility at 16, but most are at 55.

Earlier this month, Alaska became the first U.S. state to make vaccine available to everyone 16 and older and currently has one of the highest vaccination rates in the country, with 31.5% of its residents having received at least one dose, according to data from the Centers for Disease Control and Prevention.

Nearly one-fourth of Americans have received at least one dose while about 13% of the population is fully vaccinated.

(Reporting by Anurag Maan in Bengaluru; Editing by Lisa Shumaker)

Polish hospitals under strain as coronavirus cases hit 2021 record

WARSAW (Reuters) – Poland reported a record number of new coronavirus cases on Wednesday just shy of 30,000, as the pandemic cripples hospitals in some parts of the country and the government mulls sending patients to different regions to help cope.

Poland has been hit very hard by a third wave of cases and a highly contagious variant of the virus first discovered in Britain. The regions of Silesia in the south and Mazowiecki, where the capital Warsaw is located, in particular have struggled.

The government has faced criticism for failing to support the healthcare system as cases rise, while it has called on the public to observe current restrictions more closely.

“Poland’s eyes are focused on Silesia,” Health Minister Adam Niedzielski said on Wednesday, adding that the government was considering moving patients from the south to the east, where more beds are available.

In Silesia, Tuesday data showed that of 305 available respirators, 257 were occupied, while 2,894 of 3,723 hospital beds were occupied.

Doctors said the whole country’s healthcare system was struggling, however.

“We are lacking beds everywhere, let’s not fool ourselves. This is an all-Poland situation,” immunologist Pawel Grzesiowski told Reuters.

On Wednesday the number of occupied beds rose to 26,511 from 26,075, while occupied ventilators rose edged up to 2,537. The ministry said it has 35,444 hospital beds available for COVID-19 patients and 3,366 ventilators.

Poland reported 29,978 new infections on Wednesday and 575 daily coronavirus-related deaths, a record in 2021.

The country has reported 2.12 million confirmed cases overall and 50,340 deaths.

The government ordered theatres, shopping malls, hotels and cinemas to close last week as cases rose.

More restrictions loom ahead of the Easter holidays, typically marked by packed church services and family gatherings in the deeply Catholic country.

“We have to suffocate the third wave. That’s why we will announce new restrictions…that will be enforced during the week before and the week after the (Easter) holidays,” Prime Minister Mateusz Morawiecki told a news conference on Wednesday.

Those restrictions are expected to be announced on Thursday.

(Reporting by Agnieszka Barteczko, Joanna Plucinska, Alicja Ptak and Pawel Florkiewicz; Editing by Andrew Heavens and Hugh Lawson)

New U.S. COVID-19 cases show weekly uptick for first time since January

(Reuters) – New cases of COVID-19 in the United States rose 5% to more than 394,000 last week, the first increase after declining for nine straight weeks, according to a Reuters analysis of state, county and CDC data.

Thirty out of 50 states reported more new infections in the week ended March 21 compared with the previous seven days, up from 19 states in the prior week, according to the Reuters analysis.

Nationally, the weekly number of new cases had been on a downward trend since January, though health authorities have warned that infections could surge again if Americans relaxed social distancing restrictions too quickly. More infectious variants have also spread across the country.

“I am worried that if we don’t take the right actions now we will have another avoidable surge just as we are seeing in Europe right now and just as we are so aggressively scaling up vaccinations,” said Dr. Rochelle Walensky, director of the Centers for Disease Control and Prevention, on Monday.

The Northeast logged some of the highest rates of infection per capita, led by New Jersey, New York and Rhode Island.

Deaths from COVID fell 15% to 7,793 last week, or about 1,100 per day, according to the Reuters analysis. Health officials hope the country’s vaccination effort can prevent a rise in deaths even if cases surge again.

For a fourth week, daily average vaccinations set a record, with 2.5 million shots given per day last week. As of Sunday, 25% of the U.S. population has received at least one dose of a vaccine, up from 21% a week ago, according to the Centers for Disease Control and Prevention. About 13% has received two doses, up from 11%.

The average number of COVID-19 patients in U.S. hospitals fell 6% to 36,000, the lowest since October, according to a Reuters tally.

Hospitalizations have fallen for 10 weeks nationally, but they are rising in 18 states, up from four states the previous week.

(Graphic by Chris Canipe, writing by Lisa Shumaker, editing by Tiffany Wu)

Sweden reports 5,735 new COVID-19 cases, 26 deaths on Friday

STOCKHOLM (Reuters) – Sweden, which has shunned lockdowns throughout the pandemic, registered 5,735 new coronavirus cases on Friday, health agency statistics showed.

The country of 10 million inhabitants registered 26 new deaths, taking the total to 13,262. The deaths registered have occurred over several days and sometimes weeks.

Sweden’s death rate per capita is many times higher than that of its Nordic neighbors’ but lower than in several European countries that opted for lockdowns.

(Reporting by Johan Ahlander, Editing by Helena Soderpalm)

Germany, Italy, France to halt AstraZeneca shots, further hitting EU vaccination campaign

By Thomas Escritt and Stephanie Nebehay

BERLIN/GENEVA (Reuters) – Germany, France and Italy said on Monday they would stop administering the AstraZeneca COVID-19 vaccine after several countries reported possible serious side-effects, throwing Europe’s already struggling vaccination campaign into disarray.

Denmark and Norway stopped giving the shot last week after reporting isolated cases of bleeding, blood clots and a low platelet count. Iceland and Bulgaria followed suit and Ireland and the Netherlands announced suspensions on Sunday.

The moves by some of Europe’s largest and most populous countries will deepen concerns about the slow rollout of vaccines in the region, which has been plagued by shortages due to problems producing vaccines, including AstraZeneca’s.

Germany warned last week it was facing a third wave of infections, Italy is intensifying lockdowns and hospitals in the Paris region are close to being overloaded.

German Health Minister Jens Spahn said that although the risk of blood clots was low, it could not be ruled out.

“This is a professional decision, not a political one,” Spahn said adding he was following a recommendation of the Paul Ehrlich Institute, Germany’s vaccine regulator.

France said it was suspending the vaccine’s use pending an assessment by the EU medicine regulator due on Tuesday. Italy said its halt was a “precautionary and temporary measure” pending the regulator’s ruling.

Austria and Spain have stopped using particular batches and prosecutors in the northern Italian region of Piedmont earlier seized 393,600 doses following the death of a man hours after he was vaccinated. It was the second region to do so after Sicily, where two people had died shortly after having their shots.

The World Health Organization appealed to countries not to suspend vaccinations against a disease that has caused more than 2.7 million deaths worldwide.

“As of today, there is no evidence that the incidents are caused by the vaccine and it is important that vaccination campaigns continue so that we can save lives and stem severe disease from the virus,” WHO spokesman Christian Lindmeier said.

The United Kingdom said it had no concerns, while Poland said it thought the benefits outweighed any risks.

“UNUSUAL” SYMPTOMS

AstraZeneca’s shot was among the first and cheapest to be developed and launched at volume since the coronavirus was first identified in central China at the end of 2019 and is set to be the mainstay of vaccination programs in much of the developing world.

Thailand announced plans on Monday to go ahead with the Anglo-Swedish firm’s shot after suspending its use on Friday but Indonesia said it would wait for the WHO to report.

The WHO said its advisory panel was reviewing reports related to the shot and would release its findings as soon as possible. But it said it was unlikely to change its recommendations, issued last month, for widespread use, including in countries where the South African variant of the virus may reduce its efficacy.

The European Medicines Agency (EMA) has also said there was no indication the events were caused by the vaccination and that the number of reported blood clots was no higher than seen in the general population.

The handful of reported side-effects in Europe have upset vaccination programs already under pressure over slow rollouts and vaccine skepticism in some countries.

The Netherlands said on Monday it had seen 10 cases of possible noteworthy adverse side-effects from the AstraZeneca vaccine, hours after the government put its vaccination program on hold following reports of potential side-effects in other countries.

Denmark reported “highly unusual” symptoms in a 60-year-old citizen who died from a blood clot after receiving the vaccine, the same phrase used on Saturday by Norway about three people under the age of 50 it said were being treated in hospital.

“It was an unusual course of illness around the death that made the Danish Medicines Agency react,” the agency said in a statement late on Sunday.

One of the three health workers hospitalized in Norway after receiving the AstraZeneca shot had died, health authorities said on Monday, but there was no evidence that the vaccine was the cause. They said they would continue their probe and that no more suspected cases had been reported since Saturday.

AstraZeneca said earlier it had conducted a review covering more than 17 million people vaccinated in the European Union and the UK which had shown no evidence of an increased risk of blood clots.

Investigations into potential side-effects are complicated as the history of each case and circumstances surrounding a death or illness are examined. Austrian authorities have said their review of the AstraZeneca batch will take about two weeks.

The EMA has said that as of March 10, a total of 30 cases of blood clotting had been reported among close to 5 million people vaccinated with the AstraZeneca shot in the European Economic Area, which links 30 European countries.

The WHO said that as of March 12, more than 300 million doses of COVID-19 vaccines had been administered around the world with no deaths found to have been caused by any of them.

(Reporting by Panarat Thepgumpanat in BANKOK and Andreas Rinke and Paul Carrel in BERLIN, Angelo Amante in ROME, Christian Lowe in PARIS, Toby Sterling in AMSTERDAM, Jacob Gronholt-Pedersen in COPENHAGEN and Stanley Widianto in JAKARTA; writing by Philippa Fletcher; editing by Nick Macfie)

French coronavirus patients in intensive care highest since end November

PARIS (Reuters) – The number of people in intensive care in France who have COVID-19 is at the highest level since the end of November, health officials said on Tuesday as new infections rose slightly to 23,302 from 22,857 a week ago.

The new cases pushed the cumulative total since the start of the pandemic a year ago to 3.93 million, the health ministry reported, and the seven-day moving average of new cases was virtually steady at 21,333.

While France has been registering over 20,000 new cases per day since late January, week-on-week increases have slowed from nearly five percent in mid-January, when a tighter curfew at 6 p.m. was imposed, to less than four percent over the past five days.

But despite a vaccination campaign focused on the oldest and most vulnerable people, those in intensive care with COVID-19 has risen steadily from less than 3,000 people at the end of January to nearly 4,000 on Tuesday.

The number of COVID-19 patients in intensive care units was up by 69 to 3,918 people, the most since the of November, in the last days of the second month-long lockdown. That month, ICU numbers peaked at just under 5,000.

In the Paris region alone, almost 1,000 people are in ICU with COVID-19, but the government is not planning to put the Ile-de-France region around the capital into lockdown, France’s public health chief said.

He said lockdown would be a last-resort measure imposed only if the hospital system could no longer cope.

The health ministry also reported on Tuesday that 4.15 million people, or 7.9 % of the adult population, had received a first coronavirus vaccine and 2.04 million had also received a second shot, for a total of nearly 6.2 million injections.

The government aims to vaccinate 10 million people by mid-April, 20 million by mid-May and 30 million by summer.

(Reporting by Geert De Clercq; editing by Grant McCool)

New U.S. COVID-19 cases fall 12% last week, vaccinations top 2 million a day

(Reuters) – The United States reported a 12% decline in new cases of COVID-19 last week, while vaccinations accelerated to a record 2.2 million shots per day, according to a Reuters analysis of state, county and CDC data.

New infections have dropped for eight weeks in a row, averaging 60,000 new cases per day for the week ended March 7. Deaths linked to COVID-19 fell 18% last week to 11,800, the lowest since late November and averaging 1,686 per day.

Despite the positive trends, health officials have warned that the country could see a resurgence in cases as more infectious variants of the virus have been found in nearly every state.

Dr. Anthony Fauci, the top U.S. infectious disease expert, has urged the nation to keep most pandemic restrictions in place until new cases fall to under 10,000 per day.

Thirteen out of 50 states reported more new infections last week compared with the previous seven days, down from 29 states in the prior week, according to the Reuters analysis. New Jersey, New York and Rhode Island had the highest rates of new infections per 100,000 residents.

As of Sunday, 18% of the U.S. population has received at least one dose of a vaccine and 9% has received two doses, according to the Centers for Disease Control and Prevention.

The country administered an average of 2.2 million shots per day last week, up from 1.6 million shots in the prior week.

The average number of COVID-19 patients in U.S. hospitals fell 16% to 44,000 last week, the lowest since late October, according to a Reuters tally.

Cumulatively, over 525,000 people have died from the virus in the United States, or one in every 621 residents.

(Graphic by Chris Canipe, writing by Lisa Shumaker, editing by Tiffany Wu)