Tag Archives: COVID-19

COVAX vaccine program to deliver 237 million doses to 142 nations by end-May

GENEVA/LONDON (Reuters) – The COVAX vaccine-sharing program said on Tuesday it will deliver 237 million doses of AstraZeneca’s COVID-19 shot to 142 countries by the end of May as it steps up the global roll-out of its vaccine supplies.

The timeline for the delivery of doses, made by AstraZeneca and by India’s Serum Institute, will be split into separate two-month schedules, COVAX said in a statement, with the first in February-March and the second in April-May.

“These timelines are dependent on a variety of factors including national regulatory requirements, availability of supply, and fulfillment of other criteria such as validated national deployment and vaccination plans,” the statement said.

COVAX is the World Health Organization-backed program to provide vaccines for poor and middle-income countries. It began its roll-out last week with the first deliveries of shots to Ghana and Ivory Coast.

Hailing the campaign as an “unprecedented partnership,” WHO Director-General Tedros Adhanom Ghebreyesus said Angola, Cambodia, Democratic Republic of Congo and Nigeria could also expect deliveries of COVAX-supplied vaccines on Tuesday.

“This is an unprecedented partnership that will not only change the course of the pandemic but also change the way the world responds to future health emergencies,” Tedros told a joint media briefing with the U.N. Children’s Fund UNICEF, the GAVI vaccines alliance – which co-leads COVAX – and others.

Ghanaian President Nana Akufo-Addo told the same briefing that his West African country, which this week began its inoculation campaign with COVAX doses, aimed to vaccinate 20 million people by the end of 2021.

COVAX added in a statement that as well as the first round of allocations of the AstraZeneca vaccine, some 1.2 million doses of the Pfizer-BioNTech COVID shot were also anticipated for delivery in the first quarter of 2021.

(Reporting by Emma Farge and Stephanie Nebehay in Geneva and Kate Kelland in London; Editing by Mark Heinrich)

Global COVID-19 infections up for first time in seven weeks, WHO says

ZURICH (Reuters) – The number of new coronavirus infections globally rose last week for the first time in seven weeks, the World Health Organization said on Monday.

“We need to have a stern warning for all of us: that this virus will rebound if we let it,” Maria Van Kerkhove, the WHO technical lead for COVID-19, told a briefing. “And we cannot let it.”

WHO Director-General Tedros Adhanom Ghebreyesus said the rise in cases was “disappointing but not surprising” and urged countries not to relax measures to fight the disease.

It was too early for countries to rely solely on vaccination programs and abandon other measures, he said: “If countries rely solely on vaccines, they are making a mistake. Basic public health measures remain the foundation of the response.”

Tedros noted that Ghana and Ivory Coast became the first countries on Monday to begin vaccinating people with doses supplied by COVAX, the international program to provide vaccines for poor and middle-income countries.

But he also criticized rich countries for hoarding vaccine doses, saying that it was in everyone’s interest for vulnerable people to be protected around the world.

“It’s regrettable that some countries continue to prioritize vaccinating younger healthier adults at lower risk of diseases in their own populations, ahead of health workers and older people elsewhere,” Tedros said.

Mike Ryan, the WHO’s top emergency expert, said the global fight against the coronavirus was in a better state now than it was 10 weeks ago before the roll-outs of vaccines had begun. But it was too early to say the virus was coming under control.

“The issue is of us being in control of the virus and the virus being in control of us. And right now the virus is very much in control.”

(Reporting by John Revill, Vishwadha Chander, Manojna Maddipatla; Writing by Peter Graff; Editing by Alex Richardson, Dan Grebler and Giles Elgood)

As pandemic eases elsewhere, some Caribbean states face worst outbreaks yet

By Kate Chappell and Sarah Marsh

KINGSTON (Reuters) – In Jamaica, which won praise for containing its coronavirus outbreak last year, patients now overflow into corridors on chairs and stretchers in some hospitals, prompting the Caribbean nation to open three emergency field hospitals.

While global new infections start to decline, a handful of countries across the Caribbean, including the larger islands of Jamaica and Cuba, are suffering their worst outbreaks since the start of the pandemic following social gatherings over year-end, quarantine violations by visitors and growing complacency.

The number of total confirmed cases has almost doubled in the first two months of the year in Jamaica. It has risen around fourfold in Cuba, eightfold in Barbados and around tenfold in St. Lucia and St. Vincent and the Grenadines, according to Oxford University’s Our World in Data database.

In one of the most tourism-dependent regions of the world, authorities have had to reimpose lockdowns and curfews, while reducing flights and hiking quarantine restrictions, further delaying a revival of their fragile economies.

Some Caribbean nations have started inoculating citizens – thanks, in particular, to an Indian donation of the AstraZeneca vaccine – yet broad coverage still looks far off. Cuba is launching late phase trials of two of its own vaccine candidates this month.

“Once the capacity of the health system becomes threatened, we could see a spike not only in the numbers infected but also in those dying from the disease,” Jamaican Prime Minister Andrew Holness warned in a broadcast address to the nation on Sunday.

The effect of COVID-19 in Caribbean countries has been mixed. In Jamaica, deaths have risen 1.4 times since the end of the year and now stand at 422. Cuba’s death toll of 324 is well under the world average per capital – a statistic the government largely puts down to a good healthcare system and experimental treatments – but the number of deaths has doubled there so far in 2021.

Tiny St Vincent and Grenadines registered its first COVID-19 death this year and has now had eight fatal victims.

While most of the Caribbean islands still have adequate hospital capacity to deal with the crisis, in Jamaica, all beds dedicated to COVID-19 isolation were full as of Feb. 26, according to the health ministry.

Holness announced more capacity was being added and lockdown restrictions tightened, including a new stay-at-home order for those aged 60 and above and a ban on access to beaches.

“We are not coping. We are physically and emotionally drained,” said a nurse who did not want to be named for fear of losing her job.

SLOW VACCINE ROLLOUT

Caribbean leaders have complained about difficulty accessing vaccines and hoarding by rich nations amid a slow rollout of vaccines by the United Nations-backed COVAX alliance created to ensure poor countries across the world are not left behind.

Jamaica, which has nearly 3 million inhabitants, will receive a donation from India of 50,000 vaccine doses on or before Thursday, Health minister Christopher Tufton said on Sunday at the briefing alongside Holness.

The island nation should also start receiving its 124,800 doses via the COVAX facility this month, and 1.8 million via the African Medical Supply Platform from April.

But depending on which vaccine is secured, Jamaica still needed to source up to an extra 1.5 million doses to fulfill its aim of inoculating at least 65 % of the population by March 2022, Tufton said.

The prospects for an immediate economic recovery in the face of a slow vaccine roll-out are dim, said Therese Turner-Jones, general manager of the Caribbean Country Department for the Inter-American Development Bank.

“It’s going to be another difficult two years ahead,” Turner-Jones said. “Absent a healthy environment, there is not much you are going to do that will get back to business as usual.”

The Caribbean Development Bank said last Thursday it projected growth of 3.8% in its 19 borrowing member countries this year after a contraction of 12.8% last year, with vaccine availability one risk to that forecast.

Still, Cuba could hold a ray of light. It already came through for the Caribbean in terms of sending doctors to neighboring islands throughout the pandemic.

Now, the regional biotech heavyweight says it is already mass producing two of its four vaccine candidates in order to launch late phase trials in March.

Should its vaccine candidates triumph – becoming the first Latin American homegrown COVID vaccines to be approved – then its neighbors and regional allies could benefit.

(Reporting by Kate Chappell in Kingston; Additional Reporting by Sarah Marsh in Chester, UK, and Rob Edison Sandiford in Bridgetown; Editing by Alistair Bell)

Yemenis reel from poverty, hunger as U.N. pleads for funds and war’s end

SANAA (Reuters) – Unable to find work, Ahmed Farea has sold everything including his wife’s gold to feed and house two young daughters in one small room.

Elsewhere in Yemen’s capital Sanaa, widow Mona Muhammad has work but struggles to buy anything more nutritious than rice for her four children amid high prices.

And in a nearby hospital, severely malnourished children receive lifesaving nutritional drinks.

Across the country Yemenis are exhausting their coping mechanisms, and children are starving, amid the world’s largest humanitarian crisis.

On Monday the United Nations hopes to raise $3.85 billion at a virtual pledging event to avert what the U.N. aid chief has said would be a large-scale “man-made” famine, the worst the world will have seen for decades.

“I want the war to stop so we can go back to how we were … We could buy what we wanted and could feed our children,” said Muhammad.

Yemen was a poor country with a child malnutrition problem even before the six-year war disrupted imports, inflated the currency, displaced people, collapsed government services and destroyed incomes. Then COVID-19 hammered remittances from abroad that many families relied on.

‘UNIMAGINABLY CRUEL’

“Since the war and the blockade started, and work stopped, I can’t buy anything anymore. Where am I supposed to get it from?” said Farea, who wheels his barrow daily to collect water in cans from a neighborhood tank provided for poor people.

“I sleep all morning and then have lunch at noon from whatever God supplies and that covers the rest of the day.”

His work in construction declined in the wake of the political upheaval caused by Yemen’s 2011 uprising, he said. He then sold fruit but rising prices after war broke out in late 2014 made this unprofitable.

As needs have risen in the past year, funding of the aid response has dropped, leading the U.N. and other aid agencies to scale down or close various assistance programs.

Famine has never been officially declared in Yemen but pockets of famine-like conditions have appeared for the first time in two years, the U.N. has said.

In 2018 and 2019, the U.N. prevented famine due to a well-funded aid appeal. But in 2020 the world body only received just over half the $3.4 billion it needed.

“What is happening to the people of Yemen is unimaginably cruel. Aid groups are catastrophically underfunded and overstretched. The parties to this senseless war specialize in producing suffering and the weapon of choice is hunger,” said Jan Egeland, secretary general of the Norwegian Refugee Council, on a visit to Yemen.

There has been a recent renewed push by the U.N. and the United States for a negotiated end to the war, widely seen as a proxy conflict between Saudi Arabia and Iran. New U.S. President Joe Biden has said Yemen is a priority, declaring a halt to U.S. support for the Saudi-led military campaign.

(Reporting by Reuters Yemen team,; Writing by Lisa Barrington; editing by Emelia Sithole-Matarise)

U.S. CDC says trend of decline in COVID-19 cases may be stalling

WASHINGTON (Reuters) – The head of the U.S. Centers for Disease Control and Prevention said on Friday that a recent decline in COVID-19 cases may be stalling, a development she described as concerning while urging that restrictions to fight the virus remain in place.

Dr. Rochelle Walensky told reporters the CDC was watching the concerning data closely.

The White House on Friday also urged companies to join efforts to help fight the pandemic by requiring mask wearing by employees and educating customers.

Andy Slavitt, a senior adviser on the White House’s COVID-19 response team, listed a number of companies that were taking measures to help with the pandemic fight and urged more to join.

Ford and the Gap were producing and donating millions of masks, he said, while Best Buy, Target and Dollar General were giving workers paid time off to get vaccines.

The White House is working on a broad campaign to educate Americans about the vaccine as it seeks to bring the pandemic that has killed more than 500,000 people in the United States under control.

President Joe Biden on Thursday noted concerns that later this spring supply of the vaccines would outstrip demand because of vaccine hesitancy.

(Reporting by Jeff Mason, Carl O’Donnell and Lisa Lambert; Editing by Chizu Nomiyama)

U.S. to buy at least 100,000 doses of Lilly’s COVID-19 antibody therapy

(Reuters) – Drugmaker Eli Lilly and Co said on Friday the U.S. government has agreed to buy at least 100,000 doses of its newly authorized COVID-19 dual antibody cocktail for $210 million, with doses to be delivered through March-end.

The U.S. government will have the option to purchase up to an additional 1.1 million doses through Nov. 25, the company said.

Lilly said it would begin shipping these doses immediately.

The therapy contains two antibodies bamlanivimab and etesevimab and had got U.S. emergency use authorization earlier this month.

Like rival Regeneron Pharmaceuticals Inc’s dual antibody therapy REGN-COV2, Lilly’s combo has been authorized for the treatment of mild to moderate COVID-19 in patients who are at high risk of progressing to severe disease or hospitalization.

Lilly’s therapy helped cut the risk of hospitalization and death in COVID-19 patients by 70%, according to early late-stage trial data put out in January.

Despite the government’s efforts to encourage use of the treatments to help keep people out of hospitals, the therapies have seen weak demand.

Healthcare systems have said they have been slow to ramp up use of the antibodies due to extra levels of complexity during the pandemic, including requirements for quick diagnosis times and the need to isolate infectious patients.

United States had already agreed to buy 1.45 million doses of bamlanivimab alone, Lilly said, adding that 1 million of doses have already been delivered and 450,000 additional doses will be delivered by March-end.

(Reporting by Manojna Maddipatla in Bengaluru; Editing by Shounak Dasgupta)

New coronavirus variant identified in New York: researchers

By Deena Beasley

(Reuters) – A new coronavirus variant that shares some similarities with a more transmissible and intractable variant discovered in South Africa is on the rise in New York City, researchers said on Wednesday.

The new variant, known as B.1.526, was first identified in samples collected in New York in November, and by mid-February represented about 12% of cases, researchers at Columbia University Vagelos College of Physicians and Surgeons, said on Wednesday.

The variant was also described in research originally published online February 15 by California Institute of Technology scientists. Neither study has been reviewed by outside experts.

The Columbia researchers said an analysis of publicly available databases did not show a high prevalence of coronavirus variants recently identified in South Africa and Brazil in case samples from New York City and surrounding areas.

“Instead we found high numbers of this home-grown lineage,” Dr. Anne-Catrin Uhlemann, assistant professor in the division of infectious diseases at Columbia University’s College of Physicians and Surgeons, said in a statement.

The Columbia study was designed to search genomes from patient samples for mutations associated with worrisome British, South African and Brazilian virus variants. One mutation, E484K, in a genome region encoding the virus receptor binding domain, has been shown to be an escape mutation that greatly reduces the effectiveness of monoclonal and vaccine-induced antibodies.

Of the 65 virus samples containing the E484K mutation Ho’s team identified, a handful represented cases involving the known concerning variants, but 49 of the 65 belonged to the new New York B.1.526 lineage.

Studies have shown that recently launched coronavirus vaccines are still likely to neutralize the virus and protect against severe illness, even for infections with new variants. Vaccine makers are also working to develop booster shots to combat mutated versions of the virus.

Gaza is open again, to the south. But for how long?

By Nidal al-Mughrabi

RAFAH, Gaza Strip (Reuters) – A fleet of yellow Mercedes taxis lines up outside Gaza’s newly reopened Rafah crossing into Egypt, polished again and ready to roll, but with no idea for how long.

Uncertainty is a fact of life in the Palestinian border town, where 4,500 people have crossed into Egypt in the two weeks since one of Gaza’s few lifelines to the outside world swung open on Feb. 9.

The opening eased the years-long blockade imposed by Israel and Egypt on the coastal strip, compounded by measures imposed by all sides to halt the spread of COVID-19.

It arose from political maneuvering: Egyptian-brokered mediation talks between rival Palestinian factions to smooth the way for possible elections.

But the travelers have no idea how long the gate will stay open.

“To me, Rafah crossing is my source of living. If it opens, I live, and I eat and buy clothes,” said Saif Rusrus, 21, who left school to sell pastries there. “As long as there are disputes, the crossing will continue to open and close.”

Israel and Egypt cite security concerns for the restrictions, pointing to the fact that Gaza is controlled by the Islamist militant group Hamas.

The two countries allow passage for thousands of workers and humanitarian cases each year, but most of Gaza’s two million Palestinians cannot leave.

“Gaza turns into a big prison when Rafah crossing is closed,” said hepatitis patient Uday Zaanin, 38, as he waited to board the bus.

(Reporting by Nidal Almughrabi in Rafah; Writing by Stephen Farrell in Jerusalem; Editing by Giles Elgood)

UK lowers COVID-19 alert status as pressure on hospitals eases

LONDON (Reuters) – The chief medical officers of the United Kingdom lowered their COVID-19 alert level on Thursday, citing a gradual reduction in pressure on the health service.

“Following advice from the Joint Biosecurity Center and in the light of the most recent data, the four UK Chief Medical Officers and NHS England National Medical Director agree that the UK alert level should move from level 5 to level 4 in all four nations,” Britain’s health ministry said in a statement.

Public health services in England, Scotland, Wales and Northern Ireland operate separately in most cases.

“The health services across the four nations remain under significant pressure with a high number of patients in hospital, however thanks to the efforts of public we are now seeing numbers consistently declining,” the medical officers added.

(Reporting by Andy Bruce, editing by David Milliken)

India warns of worsening COVID-19 situation, vaccinations to expand

By Krishna N. Das and Neha Arora

NEW DELHI (Reuters) – India announced an expansion of its COVID-19 vaccination program on Wednesday but warned that breaches of coronavirus protocols could worsen an infection surge in many states.

Nearly a month after the health minister declared that COVID-19 had been contained, states such as Maharashtra in the west and Kerala in the south have reported a spike in cases amid growing reluctance to wear masks and maintain social distancing.

India’s infections are the second highest in the world at 11.03 million, swelled by a further 13,742 in the past 24 hours, health ministry data showed. Deaths rose by a two-week high of 104 to 156,567.

“Any laxity in implementing stringent measures to curb the spread, especially in view of new strains of virus…, could compound the situation,” the ministry said in a statement singling out nine states and a federal territory.

India has confirmed the long-time presence of two mutant variants – N440K and E484Q – in addition to those first detected in Brazil, Britain and South Africa.

TESTS FALLING

The health ministry said that while cases in the states of Chhattisgarh, Gujarat, Kerala, Maharashtra, Madhya Pradesh and Punjab, as well as the federal territory of Jammu and Kashmir, were rising, the proportion of high-accuracy RT-PCR tests in those places was falling because many states prefer antigen tests, which are cheaper and quicker but less accurate.

The federal government is worried excessive reliance on rapid antigen tests could undercount cases, leading to real infections going unchecked and spreading the disease.

Cases have also risen in Karnataka, Tamil Nadu and West Bengal.

In the past week, a third of India’s 36 states and union territories have reported an average of more than 100 new cases each day, with Kerala and Maharashtra both registering more than 4,000, in a trend experts link to the reopening of schools and suburban train services.

Maharashtra reported 8,807 new COVID-19 cases on Wednesday, the highest in nearly five months. Of those, 1,167 were in Mumbai, India’s financial capital.

The government has also asked states to speed up vaccinations for healthcare and frontline workers. Just about 11 million people have received one or two doses in a campaign that began on Jan. 16. The target is 300 million by August.

From March 1, India will start vaccinating people above 60 and those older than 45 with health conditions free of charge in about 10,000 government hospitals and for a fee in more than 20,000 private facilities, the government said.

Earlier on Wednesday, a regulatory panel sought more data from drugmaker Dr. Reddy’s Laboratories for emergency authorization of Russia’s Sputnik V COVID-19 vaccine, a senior official with direct knowledge of the discussions said.

The Central Drugs Standard Control Organization did not immediately reply to a Reuters request for confirmation.

(Reporting by Krishna N. Das and Neha Arora; Additional reporting by Rajendra Jadhav; Editing by Mark Heinrich)