Merkel backs tougher COVID lockdown in Germany

BERLIN (Reuters) -Chancellor Angela Merkel supports demands for a short, tough lockdown in Germany to curb the spread of the coronavirus as infection rates are too high, a German government spokeswoman said on Wednesday.

Germany is struggling to tackle a third wave of the pandemic and several regional leaders have called for a short, sharp lockdown while the country tries to vaccinate more people.

“Every call for a short, uniform lockdown is right,” deputy government spokeswoman Ulrike Demmer told reporters, adding Germany was seeing a growing number of intensive care patients.

“We need a stable incidence below 100,” she said, referring to the number of cases over seven days per 100,000 inhabitants. It is currently 110.1, according to the Robert Koch Institute (RKI) for infectious diseases.

She also said the government was looking at whether nationwide, rather than regional, measures were needed.

“The range of regulations does not help acceptance,” said Demmer. While some states have imposed night-time curfews over Easter, others are experimenting with some easing of restrictions.

Merkel pressed regional leaders on March 28 to step up efforts to curb rapidly rising coronavirus infections, adding a thinly veiled threat that she would otherwise have to consider what steps could be taken on a nationwide basis.

One option would be to amend the Infection Protection Act to stipulate what should happen under certain scenarios and which could enable the federal government to enforce a nationwide lockdown without getting approval of the 16 state premiers.

Demmer said the government was still looking into this option, but that no final decision had been taken yet.

Bild newspaper reported that conservative lawmakers were currently working on a draft law to give the federal government more powers to get the third wave under control.

The majority of Germany’s federal state premiers was against bringing forward talks scheduled for April 12 on what action to take.

The number of confirmed coronavirus cases in Germany rose by 9,677 on Wednesday to more than 2.9 million, the Robert Koch Institute said. It has warned that the numbers may not yet show the full picture as not all cases were registered over Easter. Some 77,401 people have died.

(Reporting by Andreas Rinke and Michael Nienaber; Writing Madeline Chambers; Editing by Maria Sheahan, Kirsti Knolle)

UK variant of COVID-19 is now most common strain in United States: CDC

By Susan Heavey and Carl O’Donnell

WASHINGTON (Reuters) – The highly contagious variant of COVID-19 first discovered in the United Kingdom has become the most common strain of the virus in the United States as cases continue to climb, a top U.S. health official said on Wednesday.

The strain, known as B.1.1.7, was identified in Britain last fall and has since been detected in 52 jurisdictions in the United States, U.S. Centers for Disease Control and Prevention Director Dr. Rochelle Walensky told reporters at a White House briefing.

U.S. public health officials have urged Americans to get vaccinated as soon as possible in part to prevent new variants of the novel coronavirus from spreading.

The United States has also detected cases of a variant first discovered in South Africa that is thought to be resistant to some COVID-19 vaccines and treatments. That strain has been found in 36 U.S. jurisdictions, according to federal data last updated on Tuesday.

The United States is administering about 3 million COVID-19 vaccine doses per day on average over the past week, up 8% over the previous seven-day average, Walensky said.

Vaccine supply has increased significantly in the United States in recent weeks as Johnson & Johnson has begun making millions of doses of its recently authorized shots. Pfizer/BioNTech and Moderna have also recently boosted their vaccine production capacity.

Still, daily U.S. cases of novel coronavirus are averaging 63,000 over the past seven days, up 2.3% from the previous seven-day average, Walensky said.

Walensky said that the CDC has identified a number of COVID-19 outbreaks tied to youth sporting events and that communities experiencing high case counts should avoid holding such events. Testing should also happen twice a week, she said.

White House COVID-19 adviser Andy Slavitt also told reporters that the U.S. government is expanding its community health center program, which it set up in recent weeks to help get vaccines into underserved communities.

(Reporting by Susan Heavey, Jeff Mason and Carl O’Donnell; Editing by Lisa Shumaker)

Canada’s hospitals deploy artificial lungs, scramble for staff as COVID-19 hits younger patients

By Anna Mehler Paperny and Allison Martell

TORONTO (Reuters) – Younger Canadians are bearing the brunt of the nation’s latest COVID-19 surge, creating growing demand for artificial lungs and a struggle to maintain staffing in critical care units as hospitals make last-ditch efforts to save patients.

Treatment with artificial lungs, known as extracorporeal membrane oxygenation, or ECMO, is much more likely to be deployed for patients under age 65, explained Marcelo Cypel, surgical director for the extracorporeal life support program at Toronto’s University Health Network (UHN).

Last week, there were a record 19 ECMO patients at UHN, 17 of them with severe COVID-19. When the sickest COVID-19 patients’ lungs fill with fluid and mechanical ventilators can no longer do the job, artificial lungs can save lives.

By Monday, doctors had weaned some off the machines and were down to 14 ECMO patients, 12 of them with COVID-19.

The need for these artificial lungs reflects a change in Canada’s epidemic, which has taken a turn for the worse, with new cases surging and outbreaks hitting workplaces and schools.

With many seniors vaccinated and new, far more contagious coronavirus variants circulating widely, younger patients are increasingly arriving in intensive care.

“It’s very different now than the first wave, when we saw older people with comorbidities,” Cypel said. “We’re seeing more … young essential workers.”

The ECMO situation is under control for now, but things can change very quickly, Cypel cautioned.

When hospital systems in other countries were overwhelmed, they had to stop using ECMO because it requires a lot of staff – seven or more people to start the treatment.

About 55% of people who receive the therapy survive, Cypel said. However, they are often left with “severe physical limitations” from their extended hospital stay, he added.

Many of Canada’s provinces are in the grip of a worsening third COVID-19 wave, as they struggle to hasten vaccine rollouts. The country reported more than 6,200 new cases on Monday, with the percentage of people testing positive for the virus up to 3.8%.

‘SEEING BURNOUT’

In British Columbia, where hospitals are bracing for a surge in demand for intensive care unit (ICU) beds caused by the highly concerning P.1 virus variant first discovered in, and now ravaging, Brazil, critical care doctor Del Dorscheid from Vancouver’s St. Paul’s Hospital is more worried about staffing than artificial lung use.

On a given shift, he said, a third of the staff are working overtime.

“They’re working so hard to find bodies to fill those empty spots,” he said. “I wouldn’t say we’re seeing more mistakes. Not yet, anyways. But we are certainly seeing burnout.”

For ICUs, there is no end in sight. As of Tuesday, there were 497 COVID-19 patients in Ontario’s ICUs, a new high. Last week, experts advising the provincial government said that could rise to 800 by the end of April even with a new stay-at-home order – or approach 1,000 without it. The province stopped short of a new stay-at-home order.

New restrictions implemented in Ontario last week change little for hardest-hit areas. In Toronto, patios for outdoor bars and restaurants closed, and a plan to reopen salons was shelved. On Monday, hard-hit Peel, west of Toronto, moved on its own to suspend in-person classes at schools for two weeks.

Canada’s vaccination rate has picked up after a slow start, with 15% of the population getting at least one shot. But data from the Institute for Clinical Evaluative Sciences shows that the Ontario communities at highest risk of COVID-19 transmission also have the lowest rates of vaccination.

These communities tend to have a high proportion of residents unable to work from home, many of them non-white immigrants holding down jobs at high risk of virus exposure.

Some lack cars to drive to vaccination sites or paid time off to get the vaccine, said Brampton doctor Amanpreet Brar. Some of the hardest-hit neighborhoods lack pharmacies that dispense COVID-19 vaccines.

“It really reflects systemic inequities we see in our society,” said Brar. “They’re considered non-essential, while their work is considered essential.”

(Editing by Denny Thomas and Bill Berkrot)

Michigan coronavirus cases rise sharply, top daily tally among U.S. states

(Reuters) – Michigan topped the coronavirus daily tally among U.S. states on Monday after a steep rise in infections, about a month after the state eased restrictions when new cases showed a downward trend.

It reported 11,082 cases on Monday, which included Sunday and Monday’s case load as the state does not report on Sunday. Michigan’s daily COVID-19 tally is hovering close to its previous single-day peak of 10,140 new cases on Nov. 20.

Michigan is currently the worst affected U.S. state in terms of new cases and hospitalizations per 100,000 people in the week to April 5. It is the only state to report more than 7,000 new cases on Monday.

Following a slew of other states, Michigan began loosening restrictions around gatherings by increasing the capacity of gyms, restaurants, pubs, retail stores and entertainment venues in March.

Around the time when restrictions were eased in March, the state reported about 1,800 new infections a day. In the seven days to April 5, the average has surged to over 6,700 cases a day.

Nationwide, new virus infections were up for a third week in a row and hospitalizations also broke an 11-week streak of falling admissions.

Twenty-seven out of 50 U.S. states have reported increases in new cases in the past week compared with the previous seven days.

Last week, U.S. President Joe Biden urged states to pause reopening efforts with the head of the U.S. Centers for Disease Control and Prevention warning of “impending doom” if precautions are not taken seriously.

Vaccinations in the country hit a record for the sixth straight week and currently over 32% of the U.S. population has received at least one dose and more than 19% were fully vaccinated, according to the CDC.

Many U.S. states, including Michigan, have already opened vaccinations for everyone above the age of 16.

(Reporting by Roshan Abraham and Sangameswaran S in Bengaluru; Editing by Muralikumar Anantharaman and Lisa Shumaker)

Brazil’s COVID-19 death surge set to pass the worst of record U.S. wave

By Pedro Fonseca

RIO DE JANEIRO (Reuters) – Brazil’s brutal surge in COVID-19 deaths will soon surpass the worst of a record January wave in the United States, climbing well beyond an average 3,000 fatalities per day, scientists predict, as contagious new variants overwhelm hospitals.

Brazil’s overall death toll trails only the U.S. outbreak, with nearly 333,000 killed, according to Health Ministry data, compared with more than 555,000 dead in the United States.

But with Brazil’s healthcare system at the breaking point, the country could also exceed total U.S. deaths, despite having two-thirds the population, two experts told Reuters.

“It’s a nuclear reactor that has set off a chain reaction and is out of control. It’s a biological Fukushima,” said Miguel Nicolelis, a Brazilian doctor and professor at Duke University, who is closely tracking the virus.

Right-wing President Jair Bolsonaro has pushed back against mask-wearing and lockdowns that public health experts consider necessary. The country dragged its feet last year as the world raced to secure vaccines, slowing the launch of a national immunization program.

With weak measures failing to combat contagion, Brazil’s COVID-19 cases and deaths are accumulating faster than ever. On the other hand, a widespread U.S. vaccination campaign is rapidly curtailing what has been the world’s deadliest outbreak.

Nicolelis and Christovam Barcellos, a researcher at Brazilian medical institute Fiocruz, are separately predicting that Brazil could surpass the United States in both overall deaths and the record for average deaths per day.

As soon as next week, Brazil may break the record U.S. seven-day average for deaths, forecasts the Institute for Health Metrics and Evaluation (IHME) at the University of Washington. The U.S. average for daily deaths peaked at 3,285 in January.

The IHME forecast does not currently extend beyond July 1, when it projects Brazil could reach 563,000 deaths, compared with 609,000 U.S. casualties expected by then.

(Reporting by Pedro Fonseca; Writing by Jake Spring; Editing by Brad Haynes and Jonathan Oatis)

Global COVID-19 death toll surpasses 3 million amid new infections resurgence

By Roshan Abraham and Anurag Maan

(Reuters) – Coronavirus-related deaths worldwide crossed 3 million on Tuesday, according to a Reuters tally, as the latest global resurgence of COVID-19 infections is challenging vaccination efforts across the globe.

Worldwide COVID-19 deaths are rising once again, especially in Brazil and India. Health officials blame more infectious variants that were first detected in the United Kingdom and South Africa, along with public fatigue with lockdowns and other restrictions.

According to a Reuters tally, it took more than a year for the global coronavirus death toll to reach 2 million. The next 1 million deaths were added in about three months.

Brazil is leading the world in the daily average number of new deaths reported and accounts for one in every four deaths worldwide each day, according to a Reuters analysis.

The World Health Organization acknowledged the nation’s dire condition due to coronavirus, saying the country is in a very critical condition with an overwhelmed healthcare system.

“Indeed there is a very serious situation going on in Brazil right now, where we have a number of states in critical condition,” WHO epidemiologist Maria Van Kerkhove told a briefing last Thursday, adding that many hospital intensive care units are more than 90% full.

India reported a record rise in COVID-19 infections on Monday, becoming the second nation after the United States to post more than 100,000 new cases in a day.

India’s worst-affected state, Maharashtra on Monday began shutting shopping malls, cinemas, bars, restaurants, and places of worship, as hospitals are being overrun by patients.

The European region, which includes 51 countries, has the highest total number of deaths at nearly 1.1 million.

Five European countries including the United Kingdom, Russia, France, Italy and Germany constitute about 60% of Europe’s total coronavirus-related deaths.

The United States has the highest number of deaths of any country at the world at 555,000 and accounts for about 19% of all deaths due to COVID-19 in the world. Cases have risen for the last three weeks but health officials believe the nation’s rapid vaccination campaign may prevent a rise in deaths. A third of the population has received at least one dose of a vaccine.

At least 370.3 million people or nearly 4.75% of the global population have received a single dose of COVID-19 vaccine by Sunday, according to latest figures from research and data provider firm Our World in Data.

However, the World Health Organization is urging countries to donate more doses of approved COVID-19 vaccines to help meet vaccination targets for the most vulnerable in poorer countries.

 

Vaccinating adults appears to protect children around them; bar opening event linked to 46 COVID-19 cases

By Nancy Lapid

(Reuters) – The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

Vaccinating adults appears to protect children as well

New data from Israel, where health officials moved quickly to distribute the COVID-19 vaccine from Pfizer Inc and partner BioNTech SE, suggests that the vaccination of adults also protects unvaccinated people living around them. Roughly one third of Maccabi Healthcare Services (MHS) 1.95 million members – all above the age of 16 – had received at least a single vaccine dose by Jan. 30. In analyzing outcomes in 223 communities, researchers found that as the number of vaccinated adults went up, infection rates among unvaccinated MHS members in the same community went down – particularly among children. MHS is Israel’s second largest healthcare maintenance organization. “While the observed vaccine-associated protection of unvaccinated is encouraging, further studies are required to understand whether and how it might support the prospect of herd immunity and disease eradication,” the researchers concluded in the study posted on Wednesday on medRxiv ahead of peer review.

Illinois bar-opening event linked to 46 cases of COVID-19

An indoor celebration of a bar opening in rural Illinois in February led to 46 new cases of COVID-19 and wider ramifications, according to a U.S. study that serves as a caution about how such events can affect local communities. Four attendees had COVID-19-like symptoms that day. Of the 46 coronavirus infections linked to the party, there were 26 cases among patrons, three in staff members and 17 “secondary cases” in people infected by them, according to a report published on Monday in the Morbidity and Mortality Weekly Report from the U.S. Centers for Disease Control and Prevention. The secondary cases included children and residents of long-term care facilities. “Transmission associated with the opening event resulted in one school closure affecting 650 children (9,100 lost person-days of school) and hospitalization of one long-term care facility resident with COVID-19,” researchers said. “These findings demonstrate that opening up settings such as bars, where mask wearing and physical distancing are challenging, can increase the risk for community transmission of SARS-CoV-2,” researchers said. Businesses should “work with local health officials to promote behaviors and maintain environments that reduce the risk for SARS-CoV-2 transmission and develop strategies for reopening safely to prevent outbreaks in the community, such as modifying layouts and operating procedures,” they said.

Congenital heart disease does not worsen COVID-19 risks

Adults with congenital heart defects are not more likely than the average person to have severe COVID-19, or to die from it, according to an international study. Risk factors associated with poor outcomes in these individuals are the same as those associated with poor outcomes in the general public – older age, male gender, a history of heart failure, irregular heart rhythm, kidney problems, diabetes, and need for extra oxygen before becoming infected with the coronavirus, said study coauthor Dr. Jamil Aboulhosn of the UCLA Adult Congenital Heart Center. Researchers analyzed data from 1,044 adults with COVID-19 from 58 congenital heart disease centers worldwide. Even people with very complex heart defects did not appear to have an increased risk of severe COVID-19 as long as they did not already have severe signs and symptoms of heart disease, Aboulhosn said, calling the finding, “somewhat surprising.” The study was published in the Journal of the American College of Cardiology.

Stroke patients with COVID-19 have worse outcomes

Among patients who went to a hospital because they were having a stroke, those who tested positive for COVID-19 had higher odds of dying there, a new study shows. The patients with COVID-19 were also more likely to have more severe stroke and to suffer another stroke while hospitalized, researchers reported in the journal Stroke. They studied close to 42,000 patients who arrived at 458 hospitals with ischemic stroke, caused by blockages in arteries that carry blood to the brain. About 3% of the patients tested positive for COVID-19. On average, they got to the hospital as quickly as patients without coronavirus infection. After that, things slowed down. “Likely due to the need for personal protective equipment use and other precautions” by hospital staffers, it took longer for COVID-19 patients to get clot-busting treatments that reopen the clogged vessels, said study coauthor Dr. Gregg Fonarow of the University of California, Los Angeles. The study cannot prove that treatment delays caused the worse outcomes. However, Fonarow said, “these findings suggest there is a need to further enhance stroke protocols to provide more timely diagnosis and treatment for patients with (ischemic stroke) to speed care while still protecting healthcare workers from exposure.”

(Reporting by Nancy Lapid, Marilynn Larkin and Megan Brooks; Editing by Bill Berkrot)

U.S. says 165 million doses of COVID-19 vaccine been administered so far

(Reuters) – The United States has administered more than 165 million doses of COVID-19 vaccines in the country as of Sunday morning and distributed nearly 208 million, the U.S. Centers for Disease Control and Prevention (CDC) said on Sunday.

That is up from the 161,688,422 vaccine doses the CDC said had gone into arms by Saturday out of 207,866,645 doses delivered.

The agency said 106,214,924 people had received at least one vaccine dose, while 61,416,536 people have been fully vaccinated as of Sunday.

The CDC tally includes two-dose vaccines from Moderna Inc and Pfizer/BioNTech,, as well Johnson & Johnson’s one-shot vaccine as of 6:00 a.m. ET on Sunday.

A total of 7,742,126 vaccine doses have been administered in long-term care facilities, the agency said.

(Reporting by Aishwarya Nair in Bengaluru; Editing by Bill Berkrot)

U.S. COVID-19 cases rise for third straight week, hospitalizations also up

(Reuters) – New cases of COVID-19 in the United States rose 5% to more than 450,000 last week, the third week in a row that infections have increased, according to a Reuters analysis of state and county data.

The average number of COVID-19 patients in hospitals rose 4% to more than 37,000 in the week ended April 4, breaking a streak of 11 weeks of falling admissions.

Health officials have expressed concerns about the increase in travel around the Easter holiday and school spring breaks, at a time when more infectious variants of the coronavirus are circulating.

While flu viruses tend to be seasonal, with cases falling as the weather warms, health officials said they have not seen similar trends with the novel coronavirus, pointing to a surge in COVID-19 cases in some regions last summer.

“I don’t think we should even think about relying on the weather to bail us out of anything we’re in right now,” Dr. Anthony Fauci, the nation’s top infectious disease expert, said at a news briefing on Monday.

Twenty-seven out of 50 states reported increases in new cases last week compared with the previous seven days, according to the Reuters analysis.

Per 100,000 people, Michigan, New Jersey and New York reported both the highest number of new cases and the highest number of hospitalizations.

Deaths from COVID-19, which tend to lag infections by several weeks, fell 17% to about 5,800 last week, or about 834 per day. Health officials have said the country’s vaccination effort could limit deaths even with rising cases.

For a sixth week, vaccinations set a record, with an average of 3.1 million shots given per day last week. As of Sunday, 32% of the U.S. population has received at least one dose and 19% was fully vaccinated, according to the CDC.

(Graphic by Chris Canipe, writing by Lisa Shumaker, editing by Tiffany Wu)

India’s daily virus cases breach 100,000; mutants, behavior blamed

By Neha Arora and Rama Venkat

NEW DELHI (Reuters) -India reported a record rise in COVID-19 infections on Monday, becoming the second country after the United States to post more than 100,000 new cases in a day, as politicians stage massive election rallies raising fears of further spreading the virus.

Hospitals in the worst affected state, Maharashtra, are being overrun by patients. India’s richest state, home to its commercial capital Mumbai and numerous industries, reported a record 57,074 new cases overnight.

The country’s daily infections have risen about 12 fold since hitting a multi-month low in early February, when authorities eased most restrictions and people largely stopped wearing masks and following social distancing.

With 103,558 new infections, India has now reported 12.6 million cases, the highest after the United States and Brazil, data from the health ministry showed. Deaths jumped by 478, still one of the lowest fatality rates in the world, raising the total to 165,101.

India has recorded the most number of infections in the past week anywhere in the world. More infectious variants of the virus may have played a role in the second surge, some epidemiologists say.

“The new variant, or variants of concern, probably explains a lot of it, rather than simplistic explanation of behavior,” said Rajib Dasgupta, head of the Center of Social Medicine & Community Health in New Delhi’s Jawaharlal Nehru University.

India has found hundreds of cases of the virus variants first detected in the United Kingdom, South Africa and Brazil.

Subhash Salunke, a former WHO official who advises Maharashtra on its COVID-19 strategy, said cases in the state would continue to rise for another couple of weeks. He said a way out was vaccinating all adults in its hardest-hit cities such as Mumbai, Pune and Nashik.

“If we start doing this, by the end of April we will see a downward trend,” he said.

VACCINE RAMP-UP

India, the world’s biggest maker of vaccines, has injected 77 million doses at home since starting its campaign in the middle of January – the third highest after the United States and China.

India’s per capita COVID-19 vaccinations, however, are lower than many other countries, including that of more populated China that started giving shots to its citizens much earlier.

India is currently vaccinating only people above the age of 45, having covered health and front-line workers first with the AstraZeneca shot and a government-backed one.

In a meeting held by Indian Prime Minister Narendra Modi on Sunday, officials discussed raising the country’s vaccine output further. The government has in recent weeks slowed vaccine exports, after shipping more than 65 million doses.

“It was highlighted that all efforts are underway to secure adequate quantities of vaccines to meet the rising domestic requirements as well as to meet the genuine needs of other countries,” his office said in a statement.

Though cases have risen exponentially in nearly a dozen states, politicians and ministers are still addressing election rallies attended by tens of thousands of mask-less people jostling for space.

The health minister in the northeastern state of Assam, currently voting to elect a new government, was ridiculed on social media on the weekend after saying there was no need for masks in his state and that wearing one hurts businesses like beauty parlors.

Maharashtra will start shutting shopping malls, cinemas, bars, restaurants and places of worship from Monday evening. Authorities will also impose a complete lockdown at weekends, as experts worried about a shortage of critical-care beds in hospitals, especially in its smaller cities.

The rise in cases has pulled down the stock market.

(Reporting by Rama Venkat Bengaluru and Neha Arora in New Delhi; Writing by Krishna N. Das; Editing by Himani Sarkar and Michael Perry)