Nearly 38 million doses of COVID-19 vaccines distributed, 17.5 million administered: U.S. CDC

(Reuters) – The U.S. Centers for Disease Control and Prevention said it had administered 17,546,374 doses of COVID-19 vaccines in the country as of Thursday morning and distributed 37,960,000 doses.

The tally of vaccine doses are for both Moderna and Pfizer/BioNTech, vaccines as of 9:00 a.m. ET on Thursday, the agency said.

According to the tally posted on Jan. 20, the agency had administered 16,525,281 doses of the vaccines, and distributed 35,990,150 doses.

The agency said 15,053,257 people had received 1 or more doses while 2,394,961 people have got the second dose as of Thursday.

A total of 2,089,181 vaccine doses have been administered in long-term care facilities, the agency said.

(Reporting by Trisha Roy in Bengaluru)

Spain opens 200 criminal probes into care home pandemic failings

MADRID (Reuters) – Spain’s public prosecutor is investigating more than 200 cases of potential criminal mishandling of the coronavirus pandemic at nursing homes, where the virus spread almost unchecked during the devastating first wave.

Nearly 43,000 care home residents died of COVID-19 or suspected infection during the March-May first wave of contagion, according to official data.

At the time, staff reported shortages of basic protective equipment and army units deployed on disinfection missions discovered unattended bodies at several facilities.

The prosecutor’s office said nearly half of its investigations related to homicide through a neglect of duty of care, while it was looking into 21 cases of deficiencies in medical treatment.

With Spain reporting record infection numbers on an almost daily basis, it warned that risks still remained across the care home network, despite improvements made in recent months.

“The increase in general contagion is still a risk for residential environments,” it said in a statement on Thursday, adding that it would continue to closely monitor the situation.

Pre-existing weaknesses, including governance, funding, working conditions, a lack of coordination with primary health care, and a lack of isolation spaces, are still widespread, the report said.

Prosecutors shelved other cases, most of the time after charges were rolled into other cases or passed to courts, rather than because investigators found no evidence of wrongdoing.

Spain has about 5,500 nursing homes, housing some 400,000 people, according to the European Ageing Network, which represents both individual carers and businesses.

The heads of both Spain’s main care home associations said they needed more information on the investigations before commenting. In the past, the associations have blamed the government for failing to provide adequate supplies and the health service for refusing to admit residents with a positive diagnosis to hospitals.

(Reporting by Nathan Allen, Belén Carreño, Emma Pinedoñ; Editing by Ingrid Melander and Andrew Cawthorne)

U.S. labor market gradually healing; housing, manufacturing power ahead

By Lucia Mutikani

WASHINGTON (Reuters) – The number of Americans filing new applications for unemployment benefits decreased modestly last week as the COVID-19 pandemic tears through the nation, raising the risk that the economy shed jobs for a second straight month in January.

Despite the labor market woes, the economy remains anchored by strong manufacturing and housing sectors. Other data on Thursday showed homebuilding and permits for future residential construction surged in December to levels last seen in 2006. Factory activity in the mid-Atlantic region accelerated this month, with manufacturers reporting a boom in new orders.

The services sector has borne the brunt of the coronavirus crisis, disproportionately impacting lower-wage earners, who tend to be women and minorities. Addressing the so-called K-shaped recovery, where better-paid workers are doing well while lower-paid workers are losing out, is one of the major challenges confronting President Joe Biden and his new administration.

Initial claims for state unemployment fell 26,000 to a seasonally adjusted 900,000 for the week ended Jan. 16, the Labor Department said. Economists polled by Reuters had forecast 910,000 applications in the latest week.

Unadjusted claims dropped 151,303 to 960,668 last week. Economists prefer the unadjusted number because of earlier difficulties adjusting the claims data for seasonal fluctuations due to the economic shock caused by the pandemic. Including a government-funded program for the self-employed, gig workers and others who do not qualify for the regular state unemployment programs 1.4 million people filed claims last week.

Out-of-control coronavirus infections are disrupting operations at businesses like restaurants, gyms and other establishments where crowds tend to gather, reducing hours for many workers and pushing others out of employment.

Consumers are also hunkering down at home, leading to a weakening in demand. COVID-19 has infected more than 24 million people, with the death toll exceeding 400,000 since the pandemic started in the United States.

U.S. stocks opened higher as investors bet on more pandemic relief and speedy vaccine rollouts under the Biden administration. The dollar fell against a basket of currencies. U.S. Treasury prices were lower.

Some of the elevation in claims reflects people re-applying for benefits following the government’s recent renewal of a $300 unemployment supplement until March 14 as part of the nearly $900 billion in additional fiscal stimulus. Programs for the self-employed, gig workers as well as those who have exhausted their benefits were also extended.

Claims data is also difficult to adjust for seasonal fluctuations at the start of the year, a task that has been made even harder given the shock caused by the coronavirus.

MOMENTUM WANING

Nevertheless, recent data have shown the labor market recovery has stalled. The claims data covered the week during which the government surveyed establishments for the nonfarm payrolls component of January’s employment report. Claims were little changed between the December and January survey period.

The economy shed 140,000 jobs in December, the first job losses since April when authorities throughout the country enforced stay-at-home measures to slow the spread of the virus. Retail sales fell for a third straight month in December.

Though jobless claims have dropped from a record 6.867 million in March, they remain above their 665,000 peak during the 2007-09 Great Recession.

The claims report showed the number of people receiving benefits after an initial week of aid decreased 127,000 to 5.054 million during the week ending Jan. 9.

About 16 million people were on unemployment benefits under all programs at the start of the year. The economy has recovered 12.4 million of the 22.2 million jobs lost in March and April. Economists say it could take several years for the labor market to recover from the pandemic.

In a separate report on Thursday, the Commerce Department said housing starts jumped 5.8% to a seasonally adjusted annual rate of 1.669 million units last month, the highest level since September 2006. Economists had forecast starts would rise to a rate of 1.560 million units in December. Starts totaled 1.380 million in 2020, up 7.0% from 2019.

Permits for future homebuilding accelerated 4.5% to a rate of 1.709 million units in December, the highest since August 2006. Permits, which typically lead starts by one to two months, totaled 1.452 million last year, a 4.8% increase from 2019.

The housing market is being underpinned by cheaper mortgages and an exodus from city centers to suburbs and other low-density areas as companies allow employees to work from home and schools shift to online classes because of the pandemic. About 23.7% of the labor force is working from home.

A third report from the Philadelphia Federal Reserve showed its business conditions index soared to a reading of 26.5 this month from 9.1 in December. A measure of new orders at factories in the region that covers eastern Pennsylvania, southern New Jersey and Delaware, vaulted to a reading of 30.0 from 1.9 in December.

Factory employment measures also improved. While manufacturers reported paying more for raw materials, they were also able to increase prices for their goods. Manufacturers were upbeat about capital investment plans in the six months ahead.

(Reporting By Lucia Mutikani; Editing by Andrea Ricci)

Trapped China gold miners have to wait 15 days for rescue

By Emily Chow

QIXIA, China (Reuters) – Workers trapped in a gold mine in China since Jan. 10 may have to wait another 15 days before they can be rescued because of a blockage on their intended escape route, officials said on Thursday.

A total of 22 workers were trapped underground after an explosion at the Hushan mine in Qixia, a major gold-producing region under the administration of Yantai in Shandong province on the northeast coast.

One is confirmed to have died, while 11 are known to be alive. The remaining 10 are missing.

Rescuers were drilling new shafts on Thursday to reach 10 of the men in the middle section of the mine, more than 600 meters from the entrance, who have been sent food and medical supplies. Another survivor has been found in a different section.

The shafts include one 711-mm (28-inch) diameter shaft that rescuers hope to use to bring the survivors to safety.

However, at least another 15 days may be needed to clear obstacles, Gong Haitao, deputy head of Yantai’s propaganda department, told a news conference at the headquarters of the rescue operation.

A “severe blockage” 350 meters down was much worse than feared, officials said, adding that it was about 100 meters thick and weights some 70 tonnes.

Thick smog, reeking of chemicals, hung over the muddy road leading up to the mine site and a row of ambulances on standby in a carpark, reducing visibility to a few hundred meters.

Police have sealed off the road to the mine, cutting through muddy apple orchards and warehouses, to ensure rescue efforts are not hampered. Health workers in white protective gear took temperatures beside mounded earth and tents as part of COVID-19 precautions.

About 600 people are involved in the rescue, with as many as 25 ambulances waiting at the scene, as well as neurosurgeons, trauma specialists and psychologists.

A Reuters team saw fire trucks and cars coming and going through a checkpoint on an approach road.

China’s mines are among the world’s deadliest. It has recorded 573 mine-related deaths in 2020, according to the National Mine Safety Administration.

(Reporting by Emily Chow in Qixia; Writing by David Stanway, Gabriel Crossley and Michael Perry and Tom Daly; Editing by Robert Birsel and Gerry Doyle)

Spaniards becoming numb to coronavirus deaths, nurse warns

By Luis Felipe Castilleja

BARCELONA (Reuters) – The senior nurse in the intensive care unit of Barcelona’s Sant Pau Hospital is anxiously watching the wards fill up and fears that Spaniards are letting their guard down against the coronavirus, numbed by the daily litany of deaths.

Staff at the unit kept up a fast pace on Thursday. Wearing double masks, goggles and gowns, they fitted patients with tubes to assist their breathing or helped them into comfortable positions.

Spain has the world’s fourth-highest number of new daily infections in a seven-day average, with 2.4 million confirmed total cases, according to a Reuters tally. It reported 41,576 new cases on Wednesday, while deaths rose by 464 to a total of 54,637.

“In the news they keep saying 300, 400 (deaths each day) and it looks like if they were talking about nothing,” ICU supervisor Mar Vega told Reuters.

“I believe people are becoming numb to these figures. They hear them but it’s like nothing is happening. People are not truly conscious of what we are going through.”

Vega said the increase in hospitalizations reminded her of the pandemic’s start last March and that medical staff risked burning out.

“It’s been many months. We are very tired.”

About 120 patients are currently hospitalized in Sant Pau for coronavirus, with 35 in the ICU, out of about 500 available beds, its director of intensive medicine, Dr. Jordi Mancebo, said. These were the worst figures since after the first wave in the spring.

Catalonia region has the highest number of accumulated hospitalizations in Spain. New admissions have doubled in the past three weeks to 600, Mancebo said.

“It’s very frustrating that there are people who minimize the importance of the pandemic,” he said.

(Reporting by Luis Felipe Castilleja, additional reporting and writing by Joan Faus,; Editing by Ingrid Melander and Angus MacSwan)

South African virus variant may resist antibody drugs; Pfizer/BioNTech vaccine seems to work vs UK variant

By Nancy Lapid

(Reuters) – The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

South African variant may resist current antibody treatments

The variant of the new coronavirus identified in South Africa can resist, or “escape,” antibodies that neutralize earlier versions of the virus, scientists have found. It “exhibits complete escape” from three classes of monoclonal antibodies manufactured for treating COVID-19 patients, and it shows “substantial or complete” resistance to neutralizing antibodies in blood donated by COVID-19 survivors, the scientists reported on Tuesday on bioRxiv ahead of peer review. Similarities between the South Africa variant and another variant identified in Brazil suggest the Brazilian variant will show similar resistance, they added. Liam Smeeth of the London School of Hygiene and Tropical Medicine, who was not involved in the study, noted that these were laboratory tests, and it would be unwise to extrapolate the findings to humans at this point. “The data do raise the possibility that the protection gained from past infection with COVID-19 may be lower for re-infection with the South African variant,” he said. “The data also suggest that the existing vaccines could be less effective against the South African variant.” He called for large studies among populations where the variant is common.

Pfizer/BioNTech shot likely protects against UK variant

The COVID-19 vaccine from Pfizer Inc and BioNTech SE is likely to protect against the more infectious variant of the virus discovered in Britain and now spreading around the world, according to laboratory tests. Researchers took blood samples from 16 people who had received the vaccine and exposed the blood to a synthetic virus, or pseudovirus, that was engineered to have 10 mutations found in the UK variant. The antibodies that had developed in response to the vaccine effectively neutralized the pseudovirus, according to a report posted on Tuesday on bioRxiv ahead of peer review. “This makes it very unlikely that the UK variant will escape from the protection provided by the vaccine,” said Jonathan Stoye, a virus scientist at Britain’s Francis Crick Institute who was not involved in the research. Similar experiments are needed with the more concerning variant first found in South Africa, he suggested. AstraZeneca Plc, Moderna Inc and CureVac NV are also testing whether their respective vaccines will protect against the fast-spreading variants.

Immune system will remember how to make COVID-19 antibodies

People who have recovered from COVID-19 can likely mount a fast and effective response to the virus if they encounter it again because their immune system’s “B cells” will remember how to make the antibodies needed to fight it, a new study shows. Researchers tracked 87 COVID-19 survivors for six months and found that while levels of antibodies to the virus may decline over time, the number of memory B cells remains unchanged. The antibodies produced by these cells are more potent than the patients’ original antibodies and may be more resistant to mutations in the spike protein the virus uses to break into cells, they said. For example, they found, the antibodies could recognize and neutralize at least one of the mutations in the South African variant of the virus that has caused concern among health experts. Even if antibody levels fall, B cells will remember how to make them when necessary, according to study leader Michel Nussenzweig of Rockefeller University, whose findings were reported on Monday in Nature. If this is true at six months, as in this study, it is safe to assume it is probably still true for longer periods, he added. People who have recovered from COVID-19 “may become infected but the immune system will be prepped to fight off the infection,” Nussenzweig said.

Mortality higher when ICUs are packed with COVID-19 patients

The more full an intensive care unit (ICU) is with COVID-19 patients, the higher the mortality rate among those patients, new data suggest. When researchers tracked outcomes of 8,515 COVID-19 patients admitted to 88 U.S. Veterans Affairs hospitals in 2020, they found that survival rates improved between March and August. Throughout the study period, however, the risk of death was nearly double when at least 75% of ICU beds were filled with COVID-19 patients, compared to when they accounted for no more than 25% of ICU beds. COVID-19 mortality “increases during periods of peak demand,” said Dr. Dawn Bravata of the Richard L Roudebush VA Medical Center in Indianapolis who co-led the study published on Tuesday in JAMA Network Open. “The more the public can do to avoid infections, the better,” she added. In addition, Bravata said, “facilities within a healthcare system or within a geographic region should collaborate to triage critically ill patients with COVID-19 to sites with greater ICU capacity to reduce strain on any one facility.”

(Reporting by Nancy Lapid, Linda Carroll, Kate Kelland and Ludwig Burger; Editing by Bill Berkrot)

35.9 million doses of COVID-19 vaccines distributed, 16.5 million administered: U.S. CDC

(Reuters) – The U.S. Centers for Disease Control and Prevention said it had administered 16,525,281 doses of COVID-19 vaccines in the country as of Wednesday morning and distributed 35,990,150 doses.

The tally of vaccine doses are for both Moderna and Pfizer/BioNTech, vaccines as of 6:00 a.m. ET on Wednesday, the agency said.

According to the tally posted on Jan. 19, the agency had administered 15,707,588 doses of the vaccines, and distributed 31,161,075 doses.

The agency said 14,270,441 people had received 1 or more doses while 2,161,419 people have got the second dose as of Wednesday.

A total of 1,908,256 vaccine doses have been administered in long-term care facilities, the agency said.

(Reporting by Mrinalika Roy in Bengaluru)

Biden to hit reset on nation’s fight against COVID-19 on his first day as president

By Susan Heavey and Patricia Zengerle

WASHINGTON (Reuters) – President Joe Biden on Wednesday will immediately reset the nation’s response to the COVID-19 crisis when he heads to the Oval Office after being sworn in to lead a country reeling from its worst public health crisis in more than a century.

As part of a first sweep of executive actions, Biden will order that all federal employees wear masks and make face coverings mandatory on federal property. He will establish a new White House office to coordinate the coronavirus response and halt the withdrawal of the United States from the World Health Organization, a process initiated by former President Donald Trump.

Biden was also poised to nominate an acting U.S. surgeon general as soon as Wednesday, a person familiar with the decision told MSNBC, following the resignation of Trump appointee Jerome Adams.

Biden’s executive actions, particularly the mask mandate, are intended to set an example for state and local officials to rein in the virus, which has hobbled the U.S. economy. The United States has reported nearly 200,000 new COVID-19 cases and 3,000 deaths per day on a seven-day rolling average, according to Reuters data. More than 123,000 Americans were hospitalized with COVID-19 as of Wednesday.

Scientists and public health experts have said face masks can help prevent the spread of the highly contagious novel coronavirus, but the coverings have become a flashpoint in American life reflecting the nation’s larger political divide.

(Reporting by Susan Heavey, Patricia Zengerle and Trevor Hunnicutt in Washington, Anurag Maan in Bengaluru, Gabriella Borter in Florida; Editing by Lisa Shumaker)

New COVID-19 variant defeats plasma treatment, may reduce vaccine efficacy

JOHANNESBURG (Reuters) – The new COVID-19 variant identified in South Africa can evade the antibodies that attack it in treatments using blood plasma from previously recovered patients, and may reduce the efficacy of the current line of vaccines, scientists said on Wednesday.

Researchers are racing to establish whether the vaccines currently being rolled out across the globe are effective against the so-called 501Y.V2 variant, identified by South African genomics experts late last year in Nelson Mandela Bay.

“This lineage exhibits complete escape from three classes of therapeutically relevant monoclonal antibodies,” the team of scientists from three South African universities working with the National Institute for Communicable Diseases (NICD) wrote in a paper published in the bioRxiv journal.

“Furthermore, 501Y.V2 shows substantial or complete escape from neutralizing antibodies in COVID-19 convalescent plasma,” they wrote, adding that their conclusions “highlight the prospect of reinfection … and may foreshadow reduced efficacy of current spike-based vaccines.”

The 501Y.V2 variant is 50% more infectious than previous ones, South African researchers said this week. It has already spread to at least 20 countries since being reported to the World Health Organization in late December.

It is one of several new variants discovered in recent months, including others first found in England and Brazil.

The variant is the main driver of South Africa’s second wave of COVID-19 infections, which hit a new daily peak above 21,000 cases earlier this month, far above the first wave, before falling to about 12,000 a day.

Convalescent blood plasma from previous patients has not been shown to be effective when administered to severely ill patients requiring intensive care for COVID-19, but it is approved in several countries as an emergency measure.

British scientists and politicians have expressed concern that vaccines currently being deployed or in development could be less effective against the variant.

The paper said it remained to be seen how effective current vaccines were against 501Y.V2, which would only be determined by large-scale clinical trials. But results showed the need for new vaccines to be designed to tackle the evolving threat, it said.

(Reporting by Tim Cocks; Editing by Peter Graff)

Netherlands proposes first curfew since World War Two, flight bans

By Bart H. Meijer

AMSTERDAM (Reuters) – The Dutch government on Wednesday proposed the first nationwide curfew since World War Two and a ban on flights from South Africa and Britain in its toughest moves yet to limit the spread of coronavirus in the Netherlands.

Prime Minister Mark Rutte said the curfew, which is largely intended to target new, more infectious variants of the disease, must be approved by parliament, which is set to debate measures against the coronavirus on Thursday.

The flight ban, which Rutte said also will apply to all South American countries, will begin on Saturday. The curfew was expected to take effect this weekend, he said.

“This is a very tough measure, but we are at a crossroads,” Rutte said in a televised news conference. “The British variant doesn’t leave us with an alternative.”

The curfew would allow only people with pressing needs to leave their homes between 8:30 p.m. and 4:30 a.m. local time, Rutte said.

Exceptions include medical emergencies, people who need to be outdoors to carry out essential jobs and walking of pets on a leash. Violators can be fined 95 euros ($115).

The government said it will also require all international travelers arriving by airplane or boat to provide proof of a second negative COVID-19 rapid test, taken just before departure. It had already required a negative test taken within 72 hours of travel.

KLM, the Dutch subsidiary of Air France KLM, said that in response to the requirement it will halt 270 weekly long-haul flights and an undetermined number of European flights to the Netherlands from Friday.

“Based on the information we have this will also count for crew members,” said KLM spokeswoman Gerrie Brand. “We cannot take the risk that crew members get stuck abroad, so we have decided to halt all long-haul flights.”

Schools and non-essential shops have already been shut since mid-December, following the closure of bars and restaurants two months earlier. They will remain shut until at least Feb. 9.

Infections in the Netherlands have decreased steadily in the past three weeks, but health authorities say the new variants will lead to a new surge by next month if social distancing measures are not tightened.

The government currently has a caretaker status, as Rutte last Friday handed his resignation to King Willem-Alexander following a damning report on his cabinet’s handling of childcare subsidies.

Rutte has said he will remain to take decisions on COVID-19 policies until a new government is formed after the March 17 elections, seeking broad support for measures from both coalition and opposition parties.

($1 = 0.8264 euros)

(Reporting by Bart Meijer; Additional reporting by Toby Sterling; Writing by Anthony Deutsch; Editing by Giles Elgood, Angus MacSwan, William Maclean)