South Carolina reports two South African variant COVID-19 cases, first in U.S.

By Julie Steenhuysen

(Reuters) – State health officials in South Carolina on Thursday said they found two cases of COVID-19 linked to a more transmissible coronavirus variant first detected in South Africa, the first cases of the mutated virus discovered in the United Sates.

Viruses are constantly changing, but the presence of the South African variant in the United States is especially concerning because several laboratory studies have shown that it reduces vaccine effectiveness.

So far, vaccines made by Moderna Inc and Pfizer Inc/BioNTech still appear protective against this variant of the coronavirus, but the companies this week said they are considering making new versions of their shots just in case. Moderna also plans to test giving a third shot of its vaccine to bolster antibody levels.

The U.S. Centers for Disease Control and Prevention said in a statement that it is aware of the cases and noted that there is no evidence the variant causes more severe disease.

The arrival of the South African variant follows predictions by the CDC this month that a more-transmissible U.K. variant could become the dominant strain in the United States by March.

CDC has said the arrival of more transmissible coronavirus variants emphasizes the need for rapid rollout of the vaccine to limit the ability of the virus to continue mutating.

(Reporting by Peter Szekely and Julie Steenhuysen in Chicago; additional reporting by Manojna Maddipatla in Bangalore; Editing by Chizu Nomiyama and David Gregorio)

39.9 million doses of COVID-19 vaccines distributed, 19.1 million administered: U.S. CDC

(Reuters) – The U.S. Centers for Disease Control and Prevention said it had administered 19,107,959 doses of COVID-19 vaccines in the country as of Friday morning and distributed 39,892,400 doses.

The tally of vaccine doses are for both Moderna and Pfizer/BioNTech, vaccines as of 9:00 a.m. ET on Friday, the agency said.

According to the tally posted on Jan. 21, the agency had administered 17,546,374 doses of the vaccines, and distributed 37,960,000 doses.

The agency said 16,243,093 people had received one or more doses, while 2,756,953 people got the second dose as of Friday.

A total of 2,289,284 vaccine doses have been administered in long-term care facilities, the agency said.

(Reporting by Trisha Roy in Bengaluru)

Severe allergic reactions to Moderna vaccine appear rare: CDC report

By Vishwadha Chander

(Reuters) – Severe allergic reactions to Moderna Inc’s coronavirus vaccine appear to be quite rare, the U.S. Centers for Disease Control and Prevention (CDC) said on Friday, after over 4 million people had received their first dose.

Based on the data, the CDC said anaphylaxis, a life-threatening allergic reaction, occurred at a rate of 2.5 cases per 1 million shots administered.

The agency cautioned that the risk of anaphylaxis was difficult to compare to non–COVID-19 vaccines because it is still so early in the vaccination program.

As of Jan. 10, there were 10 cases of anaphylaxis reported among 4.04 million people who received their first doses of Moderna’s two-shot vaccine, according to the agency’s Morbidity and Mortality Weekly Report.

The CDC said the characteristics of severe allergic reactions to Moderna’s vaccine were similar to those reported with the COVID-19 vaccine from Pfizer Inc and partner BioNTech SE.

Earlier this month, the CDC reported severe allergic reactions to the Pfizer/BioNTech shot occurred at a rate of 11.1 per 1 million vaccinations.

For both vaccines, symptoms presented within minutes after vaccination and were more common among women. Many of those who suffered anaphylaxis after receiving either vaccine had a history of allergies or allergic reactions, and several had an anaphylaxis episode in the past, the CDC said.

The agency said locations administering COVID-19 vaccines should screen recipients, have necessary supplies and staff members to manage anaphylaxis, and immediately treat suspected cases with an epinephrine injection, the same drug in EpiPens.

(Reporting by Vishwadha Chander in Bengaluru and Julie Steenhuysen in Chicago; Editing by Caroline Humer and Bill Berkrot)

Travel group opposes mandatory quarantine sought by Biden for U.S. international passengers

By David Shepardson

WASHINGTON (Reuters) – A group representing the U.S. travel industry on Friday said it opposes making quarantines mandatory for international air passengers returning to the United States.

U.S. Travel said it believes the introduction of new mandatory negative COVID-19 testing requirements for all international air passengers aged two and older eliminates the need for quarantines for returning passengers.

The new international testing requirements start Tuesday.

The group said enforcing a “mandatory quarantine requirement for international travelers could be extremely difficult to enforce”.

The Centers for Disease Control and Prevention (CDC) recommends a seven-day quarantine for passengers arriving in the United States.

U.S. President Joe Biden on Thursday issued an executive order directing agencies to require international air travelers to quarantine upon U.S. arrival, and directed U.S. agencies to implement a federal mask mandate in interstate transportation.

Biden told reporters passengers will need to “quarantine when they arrive in America”.

The White House did not comment Friday on the travel group’s concerns.

Biden’s order directed agencies to make recommendations to “impose additional public health measures for domestic travel.” Officials say Biden could require COVID-19 testing before flying domestically, similar to the incoming international requirements.

U.S. Travel Chief Executive Roger Dow said Friday the group does not think making testing mandatory before domestic travel “feasible or viable” and questions if the United States has the testing capacity.

Biden’s order says “to the extent feasible” air travelers must comply with applicable CDC guidelines concerning international travel “including recommended periods of self-quarantine”.

The Biden administration said this week it would reimpose entry bans on most non-U.S. citizens who have recently been in Brazil, the United Kingdom, Ireland and most of continental Europe after President Donald Trump issued an order on Monday lifting them from the same day the new testing rules take effect.

Biden has yet to issue a new order to reimpose those entry bans.

(Reporting by David Shepardson; Editing by Jan Harvey)

Nearly 38 million doses of COVID-19 vaccines distributed, 17.5 million administered: U.S. CDC

(Reuters) – The U.S. Centers for Disease Control and Prevention said it had administered 17,546,374 doses of COVID-19 vaccines in the country as of Thursday morning and distributed 37,960,000 doses.

The tally of vaccine doses are for both Moderna and Pfizer/BioNTech, vaccines as of 9:00 a.m. ET on Thursday, the agency said.

According to the tally posted on Jan. 20, the agency had administered 16,525,281 doses of the vaccines, and distributed 35,990,150 doses.

The agency said 15,053,257 people had received 1 or more doses while 2,394,961 people have got the second dose as of Thursday.

A total of 2,089,181 vaccine doses have been administered in long-term care facilities, the agency said.

(Reporting by Trisha Roy in Bengaluru)

35.9 million doses of COVID-19 vaccines distributed, 16.5 million administered: U.S. CDC

(Reuters) – The U.S. Centers for Disease Control and Prevention said it had administered 16,525,281 doses of COVID-19 vaccines in the country as of Wednesday morning and distributed 35,990,150 doses.

The tally of vaccine doses are for both Moderna and Pfizer/BioNTech, vaccines as of 6:00 a.m. ET on Wednesday, the agency said.

According to the tally posted on Jan. 19, the agency had administered 15,707,588 doses of the vaccines, and distributed 31,161,075 doses.

The agency said 14,270,441 people had received 1 or more doses while 2,161,419 people have got the second dose as of Wednesday.

A total of 1,908,256 vaccine doses have been administered in long-term care facilities, the agency said.

(Reporting by Mrinalika Roy in Bengaluru)

31.2 million doses of COVID-19 vaccines distributed, 12.3 million administered: U.S. CDC

(Reuters) – The U.S. Centers for Disease Control and Prevention said it had administered 12,279,180 doses of COVID-19 vaccines in the country as of Friday morning and distributed 31,161,075 doses.

The tally of vaccine doses are for both Moderna and Pfizer/BioNTech vaccines as of 6:00 a.m. ET on Friday, the agency said.

According to the tally posted on Jan. 14, the agency had administered 11,148,991 doses of the vaccines, and distributed 30,628,175 doses.

The agency said 10,595,866 people had received 1 or more doses while 1,610,524 people have got the second dose as of Friday.

A total of 1,384,963 vaccine doses have been administered in long-term care facilities, the agency said.

(Reporting by Mrinalika Roy in Bengaluru)

More transmissible UK coronavirus variant found in 10 U.S. states, CDC says

By Julie Steenhuysen

CHICAGO (Reuters) – A new, more transmissible variant of the coronavirus first discovered in Britain has been detected in 10 U.S. states, the U.S. Centers for Disease Control and Prevention said on Friday, warning that it could become the dominant circulating variant in the United States by March.

The variant, known as B.1.1.7, is believed to be twice as transmissible as the current version of the virus circulating in the United States.

Its rapid spread will increase the burden on health resources at a time when infections are surging, further sapping strained healthcare resources and increasing the need for better adherence to mitigation strategies, such as social-distancing and mask-wearing, the CDC said in its weekly report on death and disease.

It also increases the percentage of the population that needs to be vaccinated to achieve protective herd immunity to control the pandemic, the CDC said.

(Reporting by Julie Steenhuysen; Editing by Paul Simao)

U.S. tops 10 million COVID vaccinations as California expands eligibility for shots

By Peter Szekely and Dan Whitcomb

(Reuters) – More than 10 million Americans had received their first dose of a COVID-19 vaccine as of Wednesday, according to the U.S. Centers for Disease Control and Prevention, as the year-old pandemic roared on unchecked.

The United States reached 10.2 million inoculations one day after the CDC and Trump administration gave new guidance to U.S. states on who should receive the shots first. Strict rules putting healthcare workers first in line had slowed the rollout. Now states are urged to vaccinate anyone over 65 as well.

California moved on Wednesday to do just that, designating all individuals 65 and older eligible to begin receiving vaccines, adding 6.6 million people to the rolls of those qualified to be immunized, Governor Gavin Newsom said.

The move bumps senior citizens, regardless of whether they have underlying medical conditions, to the top of the priority list for vaccine recipients, just behind front-line healthcare workers and residents and staff of nursing homes.

California, like many states, has struggled to use up as much vaccine as it received in initial allotments from the federal government, administering only about a third of the nearly 2.5 million doses shipped to the state as of Monday.

Newsom has set a goal of inoculating 1 million more Californians by the end of this week with the first shot of the two-dose vaccine.

He also said the state would launch a new system next week for notifying people when they become eligible for the vaccine, and to register for notification by email or text.

The latest push to spur the most ambitious mass immunization campaign in U.S. history came as the nation set a new record for coronavirus deaths in one day, with 4,336 fatalities on Tuesday, according to a Reuters tally.

Health and Human Services Secretary Alex Azar on Tuesday said the administration was releasing its full stockpile of two vaccines approved for emergency use, including some that had been held in reserve to make sure that second doses could be given on schedule.

Nearly 30 million doses of the vaccines, manufactured by Moderna and Pfizer with its German partner BioNTech, have been released to U.S. states, which have used only about one-third of them.

Johnson & Johnson said on Wednesday that the pharmaceutical company was on track to roll out its single-shot vaccine in March.

In an interview with Reuters on Tuesday, Dr. Paul Stoffels also said J&J expected to meet its stated target of delivering 1 billion doses of its vaccine by the end of this year as the company ramps up production.

Political leaders and health officials nationwide have scrambled in recent days to push out more vaccines to their residents, many lowering the age requirement to 65. California and New York have both pledged to inoculate one million residents this month.

NEW YORK SEEKS MORE VACCINE

In New York City, Mayor Bill de Blasio, a Democrat, said on Wednesday that short supplies of the vaccine could hamper efforts to reach the city’s inoculation goals.

“We need the federal government, the state government and the manufacturers to step up and get us more supply immediately,” de Blasio told a news conference.

The nation’s most populous city is adding vaccination sites across its five boroughs, including its two Major League Baseball stadiums.

“I confirmed with our healthcare team yesterday that even with normal supplies that we expect to have delivered next week, we will run out of vaccine at some point next week, unless we get a major new resupply,” de Blasio said.

Public health officials say so far no U.S. state has used up its supply of the vaccines.

At the Javits Center in Manhattan, which was pressed into service as a temporary hospital in April, health officials said they were prepared to vaccinate 10,000 people in 12 hours, with the ability to ramp up to 25,000 in a 24-hour period.

New York has recorded nearly 40,000 coronavirus fatalities since the pandemic broke out there in March, more than any other U.S. state.

Nationwide more than 380,000 people have died of COVID-19. A total of 22.7 million have been infected during that time.

The number of COVID-19 patients requiring hospitalization may have leveled off at least temporarily, according to a Reuters tally, although public health officials warned that further spread may still be seen from holiday gatherings.

California, the nation’s most populous state, has seen new hospitalizations drop this week, according to health officials. More than 30,000 Californians have so far died of COVID-19 related illness.

The recent emergence of a more infectious variant of the virus first seen in the United Kingdom has made efforts to accelerate vaccinations all the more important. The so-called UK variant has so far been confirmed in at least 10 U.S. states.

(Reporting by Peter Szekely and Andrew Hofstetter in New York, Julie Steenhuysen in Chicago and Dan Whitcomb and Steve Gorman in Los Angeles; Editing by Cynthia Osterman, Alistair Bell and Catherine Evans)

U.S. to require negative COVID-19 tests for international air passengers: sources

By David Shepardson

WASHINGTON (Reuters) – The head of the U.S. Centers for Disease Control and Prevention (CDC) is expected to sign an order on Tuesday expanding coronavirus testing requirements for nearly all international air travelers, not just from Britain, sources briefed on the matter told Reuters.

The new rules are to take effect two weeks from the day they are signed by CDC Director Mark Redfield, which would be Jan. 26.

The CDC has been urgently pressing for an expansion of the requirements with the Trump administration for weeks. One remaining issue is how to address some countries that have limited testing capacity and how the CDC would address travel to those countries, the sources said.

The CDC on Dec. 28 began requiring almost all airline passengers arriving from Britain – including U.S. citizens – to test negative for COVID-19 within 72 hours of departure. Those under 2 and passengers connecting through the UK are exempt.

Canada imposed similar rules for nearly all international arrivals starting Jan. 7, as have many other countries.

At a White House meeting on Monday, Redfield again made an urgent case to adopt the testing requirements as new strains of COVID-19 are identified in different parts of the world. He raised concerns that vaccines could potentially not be effective against new strains, sources said.

U.S. officials do not plan to drop restrictions that were adopted starting in March that ban most non-U.S. citizens who have been in most of Europe, the United Kingdom and Brazil as soon as possible, the sources said. They added that public health officials are sympathetic to the push to lift the restrictions that apply only to a limited number of countries.

Earlier this month, major U.S. airlines backed the CDC’s push to implement a global testing program requiring negative tests for most international air passengers returning to the United States.

Airlines for America, a group that represents American Airlines, United Airlines, Delta Air Lines and other major carriers, also urged the Trump administration to lift European and Brazilian entry restrictions as part of the testing expansion.

(Reporting by David Shepardson; Editing by Chris Reese and Dan Grebler)