Mourners make Prague’s Old Town Square into somber memorial for coronavirus victims

By Jiri Skacel

PRAGUE (Reuters) – Prague residents laying flowers, scribbling names or mourning quietly have turned the Czech capital’s medieval Old Town Square into an improvised memorial to the thousands of lives lost to the COVID-19 pandemic in the past year.

A civic group called “Million Moments for Democracy” sprayed 25,000 white crosses overnight on Monday on the cobble-stoned square, surrounded by gothic and baroque churches and Prague’s famed Astronomical Clock, to commemorate victims of the pandemic in the past year — and blame the government for missteps.

The plan was to wash the crosses off that day, but Prague’s city hall said it would let them stay until rain washes them off.

Then people spontaneously started chalking names, dates of deaths and notes to individual crosses, turning the original act into personal commemorations.

Anna Vojtechova brought a flower and a small bottle of the Czech herbal liqueur Becherovka for her brother, who died aged 75 on March 1, the same day he registered for vaccination.

“He was supposed to be vaccinated and did not live to see it. He was healthy, not obese, no illness. It chewed him up. People must be hugely careful,” she said while fighting tears.

Another mourner, Petr Popov, came to remember a friend from Prague’s Bulgarian community. “I want to write his name down with chalk to pay respects,” he said.

Others, who have not been personally hit, also visit.

Monika Mudranincova said she wanted to pay her respects.

“We feel so sorry and it would be amazing if we saw a light at the end of the tunnel, but it seems there is none yet,” she said.

During the first wave of the pandemic, a year ago, the Czech government quickly shut borders, schools and retail outlets, leading the country through with minimum losses. But it was also quick to relax restrictions after the first wave and slow to build up testing and tracing capacities over the summer.

The government reacted slowly to a new surge in infections in the autumn. Another relaxation before Christmas and the spread of the more infectious British variant of the virus packed hospitals again in January and then March.

Now the central European country of 10.7 million has become one of the world’s worst-hit in the pandemic, reporting over 1.5 million coronavirus infections and 25,639 deaths, and thousands more excess deaths above normal rates.

The death toll is the highest per capita in the world apart from San Marino, according to Our World in Data website.

(Reporting by Jiri Skacel, writing by Jan Lopatka, editing by Larry King)

Pfizer, BioNTech launch COVID-19 vaccine trial in kids under 12

By Michael Erman

(Reuters) – Pfizer Inc and German partner BioNTech SE began testing their COVID-19 vaccine in children under 12, with hopes of expanding vaccination to that age range by early 2022, the U.S. drugmaker said on Thursday.

The first volunteers in the early-stage trial were given their first injections on Wednesday, Pfizer spokesperson Sharon Castillo said.

The Pfizer/BioNTech vaccine was authorized by U.S. regulators in late December for people age 16 and older. Nearly 66 million doses of the vaccine had been administered in the United States as of Wednesday morning, according to data from the U.S. Centers for Disease Control and Prevention.

The pediatric trial, which will include children as young as 6 months, follows a similar one launched by Moderna Inc last week.

Only the Pfizer/BioNTech vaccine is being used in 16- and 17-year-olds in the United States. Moderna’s shot was cleared for those age 18 and older, and no COVID-19 vaccine has been authorized in younger kids yet.

Pfizer and BioNTech plan to initially test the safety of their two-shot vaccine at three different dosages – 10, 20 and 30 micrograms – in a 144-participant Phase I/II trial.

They plan to later expand to a 4,500-participant late-stage trial in which they will test the safety, tolerability and immune response generated by the vaccine, likely by measuring antibody levels in the young subjects.

Castillo said the companies hope to have data from the trial in the second half of 2021.

Meanwhile, Pfizer has been testing the vaccine in children from age 12 to 15. The company expects to have data from that trial in the coming weeks, Castillo said.

(Reporting by Michael Erman; Additional reporting by Julie Steenhuysen in Chicago; Editing by Bill Berkrot)

U.S. COVID-19 cases top 30 million as states race to vaccinate

By Anurag Maan

(Reuters) – The United States crossed 30 million coronavirus cases on Wednesday, according to a Reuters tally, as states accelerate the vaccination process by lowering age limits.

Health authorities are racing to vaccinate in the face of the first uptick in new cases on a weekly basis since January. Against the advice of health experts, several states have lifted mask mandates and more infectious variants have also spread across the nation.

Although cases are trending higher in 30 out of 50 states compared with the previous week, health officials hope the vaccinations will prevent a rise in deaths. The United States has lost a total of 544,000 lives to the virus.

New York on Monday joined Florida and a handful of other states that have made vaccines available to people who are at least 50 years old.

In the past two weeks, many states including Alaska, Arizona and Texas have lowered down their eligibility age for coronavirus vaccines.

Arizona lowered the eligibility age to 16 at state-run vaccination sites in three populous southern counties, effective Wednesday. Three other counties already have eligibility at 16, but most are at 55.

Earlier this month, Alaska became the first U.S. state to make vaccine available to everyone 16 and older and currently has one of the highest vaccination rates in the country, with 31.5% of its residents having received at least one dose, according to data from the Centers for Disease Control and Prevention.

Nearly one-fourth of Americans have received at least one dose while about 13% of the population is fully vaccinated.

(Reporting by Anurag Maan in Bengaluru; Editing by Lisa Shumaker)

U.S. says hopes WHO report on virus origins is ‘based on science’

By Stephanie Nebehay

GENEVA (Reuters) – The United States expects the World Health Organization (WHO) investigation into the origins of the novel coronavirus pandemic to require further study, perhaps including a return visit to China, a senior U.S. official said on Wednesday.

Marc Cassayre, charge d’affaires at the U.S. mission to the U.N. in Geneva, also voiced hope that the WHO-led mission to the central city of Wuhan in Jan.-Feb. had access to the raw data and to the people required to make an independent assessment.

The lengthy report by the team – composed of international experts and their Chinese counterparts – is expected to be issued this week, the WHO says.

“We are hopeful that it will be based on science and be a real step forward for the world understanding the origins of the virus so we can better prepare for future pandemics,” Cassayre told a news briefing.

U.S. officials expected further work would be needed to identify the source of the SARS-CoV-2 virus, he said. “That would probably require, as we would presume, further studies of the team, maybe travel to China or further discussions.”

The probe was plagued by delays, concern over access and bickering between Beijing and Washington, which under former U.S. President Donald Trump’s administration accused China of hiding the extent of the initial outbreak.

Some team members have said China was reluctant to share vital data that could show the virus was circulating months earlier than first recognized in late 2019.

Ben Embarek, a WHO official leading the mission, said at a press briefing marking the end of the visit that the virus probably originated in bats, although it was not certain how it reached humans. He also effectively ruled out a lab leak.

WHO director-general Tedros Adhanom Ghebreyesus later said that “all hypotheses remain open” and pledged full transparency.

(Reporting by Stephanie Nebehay; Editing by Hugh Lawson)

Jordan cemetery struggles amid COVID-19 surge

By Suleiman Al-Khalidi

AMMAN (Reuters) – Clerks at the largest cemetery in Jordan barely have a moment to themselves as people rush to pay for graves to bury relatives amid a record surge of deaths from COVID-19.

The cemetery on the outskirts of the capital saw at least 50 burials on Tuesday, a day after the health ministry announced 109 COVID-19 deaths, the kingdom’s highest daily tally.

“We have no time to scratch our heads,” said Ahmad Jaber as he completed a 50 dinar ($70) invoice for a plot at the Amman municipal cemetery while bereaved relatives waited in line.

The surge in the last two months, blamed on the fast spread of the variant first identified in Britain, has put Jordan’s infections and deaths above most of its neighbors and reverses months of success in containing the outbreak.

The government, which says there are 3,334 COVID-19 patients in hospital, is facing a crisis with some wards at capacity, especially in the capital and surrounding provinces where over 60% of the country’s 10 million population live.

“We hope the daily infections don’t continue this way, otherwise there will be a real problem in the availability of isolation rooms and intensive care units,” said Fawzi Hammouri, the head of Jordan’s private hospital association.

Coronavirus wards in 27 private hospitals are now at 90% occupancy and intensive care units are at 78% capacity in and around the capital.

Private hospitals are considering scrapping non-urgent procedures and outpatient clinics, steps taken by public hospitals earlier this month, to create more space.

Some officials have suggested the government should use sports stadiums, refurbish old hospitals or set up beds in schools.

“The infections are heading for more increases,” said Interior Minister and acting Health Minister Mazen al Faraya.

To spare the economy, Prime Minister Bisher al Khasawneh has so far avoided a two-week lockdown recommended by medics.

The government earlier this month extended a night curfew, ordered a full Friday lockdown and imposed stricter penalties on violators of social distancing rules.

EMERGENCY WARD OVERWHELMED

At Jordan University hospital, a 100-bed ward for COVID-19 patients has been full for the past week and medics struggle to keep those patients separate from others with serious ailments, said hospital director Islam Massad.

“I hope we can control this and numbers fall because the situation is getting very difficult,” said Ahmad Saafeen, head of emergency ward.

The situation is slightly better outside big towns, where intensive care unit capacity is at 30% to 50%, according to official data.

But trust in the public health service is at a record low with gross negligence exposed after nine people, mostly COVID-19 patients, died earlier this month when medics ignored depleted oxygen supplies.

The scandal means Khasawneh is facing his toughest challenge since being appointed last October, politicians say.

Anger over the crisis, which has pushed unemployment to a record 24%, sent hundreds of demonstrators on to the streets earlier this month, defying the curfew and calling for Khasawneh’s removal.

(Additional reporting by Jehad Abu Shalbak and Muath Freij in Amman; Editing by Giles Elgood)

Polish hospitals under strain as coronavirus cases hit 2021 record

WARSAW (Reuters) – Poland reported a record number of new coronavirus cases on Wednesday just shy of 30,000, as the pandemic cripples hospitals in some parts of the country and the government mulls sending patients to different regions to help cope.

Poland has been hit very hard by a third wave of cases and a highly contagious variant of the virus first discovered in Britain. The regions of Silesia in the south and Mazowiecki, where the capital Warsaw is located, in particular have struggled.

The government has faced criticism for failing to support the healthcare system as cases rise, while it has called on the public to observe current restrictions more closely.

“Poland’s eyes are focused on Silesia,” Health Minister Adam Niedzielski said on Wednesday, adding that the government was considering moving patients from the south to the east, where more beds are available.

In Silesia, Tuesday data showed that of 305 available respirators, 257 were occupied, while 2,894 of 3,723 hospital beds were occupied.

Doctors said the whole country’s healthcare system was struggling, however.

“We are lacking beds everywhere, let’s not fool ourselves. This is an all-Poland situation,” immunologist Pawel Grzesiowski told Reuters.

On Wednesday the number of occupied beds rose to 26,511 from 26,075, while occupied ventilators rose edged up to 2,537. The ministry said it has 35,444 hospital beds available for COVID-19 patients and 3,366 ventilators.

Poland reported 29,978 new infections on Wednesday and 575 daily coronavirus-related deaths, a record in 2021.

The country has reported 2.12 million confirmed cases overall and 50,340 deaths.

The government ordered theatres, shopping malls, hotels and cinemas to close last week as cases rose.

More restrictions loom ahead of the Easter holidays, typically marked by packed church services and family gatherings in the deeply Catholic country.

“We have to suffocate the third wave. That’s why we will announce new restrictions…that will be enforced during the week before and the week after the (Easter) holidays,” Prime Minister Mateusz Morawiecki told a news conference on Wednesday.

Those restrictions are expected to be announced on Thursday.

(Reporting by Agnieszka Barteczko, Joanna Plucinska, Alicja Ptak and Pawel Florkiewicz; Editing by Andrew Heavens and Hugh Lawson)

Women in 40s, 50s who survive COVID more likely to suffer persistent problems: UK studies

By Kate Kelland

LONDON (Reuters) – Women in their 40s and 50s appear more at risk of long-term problems following discharge from hospital after COVID-19, with many suffering months of persistent symptoms such as fatigue, breathlessness and brain fog, two UK studies found on Wednesday.

One study found that five months after leaving hospital, COVID-19 patients who were also middle-aged, white, female, and had other health problems such as diabetes, lung or heart disease, tended to be more likely to report long-COVID symptoms.

“Our study finds that those who have the most severe prolonged symptoms tend to be white women aged approximately 40 to 60 who have at least two long term health conditions,” said Chris Brightling, a professor of respiratory medicine at Leicester University who co-led the study known as PHOSP-COVID.

A second study led by the International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) found that women under 50 had higher odds of worse long-term health outcomes than men and than older study participants, even if they had no underlying health conditions.

“It’s becoming increasingly clear that COVID-19 has profound consequences for those who survive the disease,” said Tom Drake, a clinical research fellow at Edinburgh University who co-led the ISARIC study.

“We found that younger women were most likely to have worse long-term outcomes.”

The ISARIC study, which covered 327 patients, found that women under 50 were twice as likely to report fatigue, seven times more likely to have breathlessness, and also more likely to have problems relating to memory, mobility and communication.

The PHOSP study analyzed 1,077 male and female patients who were discharged from hospitals in Britain between March and November 2020 after having COVID-19.

A majority of patients reported multiple persistent symptoms after 5 months, with common symptoms being muscle and joint pain, fatigue, weakness, breathlessness and brain fog.

More than a quarter had what doctors said were “clinically significant symptoms of anxiety and depression” at five months, and 12% had symptoms of post-traumatic stress disorder (PTSD).

Louise Wain, a professor and respiratory specialist at Leicester University who co-led PHOSP, said differences in male and female immune responses “may explain why post-COVID syndrome seems to be more prevalent” in women.

“We…know that autoimmunity, where the body has an immune response to its own healthy cells and organs, is more common in middle-aged women,” she said, but “further investigation is needed to fully understand” the processes involved.

(Reporting by Kate Kelland; Editing by Bernadette Baum)

Doctors in Hungary urge volunteers to join overwhelmed COVID-19 wards

BUDAPEST (Reuters) – An appeal went out on Monday for volunteers to join hospital staff treating coronavirus patients in northwestern Hungary, as doctors said COVID-19 wards were overwhelmed, with the pressure only set to mount during the next few weeks.

New infections are surging in Hungary, hard-hit by the third wave of the pandemic, despite vaccination rates at the top of European Union nations, as a proportion of population.

Hungary was the first nation in the bloc to buy and use Chinese or Russian vaccines, as it said shipments from Western suppliers lagged.

Monday’s call, posted on the Facebook page of the Hungarian Medical Chamber in the county of Gyor-Sopron, came just as the nation reported a record number of 11,276 patients in hospital, with 1,340 of them on ventilators.

“The COVID-19 departments in almost all the hospitals are hugely overburdened, there is a shortage of nurses and they are becoming increasingly exhausted,” Laszlo Szijjarto, the chairman of the county chamber, said in the request.

He called for motivated and reliable volunteers to enroll in a 3 hour to 4 hour training course to join hospital staff and assist in monitoring and caring for patients.

The spreading third wave presents a big challenge for nationalist Prime Minister Viktor Orban, who aims to get as many people immunized as quickly as possible to reopen the economy.

Hungary still had plenty of free beds to treat coronavirus patients, Orban said on Friday.

“We haven’t even reached half our capacity yet,” he said, referring to the tally of beds with ventilators, while adding that the number of those free, but without ventilators, exceeded 10,000.

“The question is always whether there are enough doctors and nurses to operate these,” Orban added, saying problems would be resolved.

With just over 1.589 million Hungarians inoculated, Orban said lockdown measures could start to ease once the figure reached 2.5 million, or a quarter of the population.

(Reporting by Krisztina Than; Editing by Clarence Fernandez)

Austria delays reopening restaurants as COVID-19 cases rise

VIENNA (Reuters) – Austria has postponed the reopening of café, restaurant and bar terraces planned for March 27 due to rising coronavirus cases and is preparing for regions to adapt restrictions locally, the government said on Monday.

Infections have been increasing steadily since Austria loosened its third lockdown on Feb. 8 by letting non-essential shops reopen despite stubbornly high COVID-19 cases. A night-time curfew replaced all-day restrictions on movement.

The number of new infections reported rose above 3,500 on Friday, the highest level since early December, when cases were falling during the second national lockdown.

The government met with the governors of its nine provinces on Monday to review its plan to let terraces reopen next weekend in all but one of them, after the small Alpine province of Vorarlberg got a head start earlier this month.

“The experts have advised us not to carry out any more loosening of restrictions here, unfortunately,” Chancellor Sebastian Kurz said of most provinces, adding three hard-hit eastern ones including Vienna would work on extra measures.

A government source said loosening of restrictions could happen in some regions after Easter if intensive-care figures are stable.

Last week the hardest-hit provinces were Vienna and the province surrounding it, Lower Austria, as well as Burgenland, which borders Hungary. The latest government data shows them in the top five in terms of infection rates and intensive care bed use, with Salzburg and Upper Austria.

(Reporting by Francois Murphy; Editing by Andrew Cawthorne and Janet Lawrence)

New U.S. COVID-19 cases show weekly uptick for first time since January

(Reuters) – New cases of COVID-19 in the United States rose 5% to more than 394,000 last week, the first increase after declining for nine straight weeks, according to a Reuters analysis of state, county and CDC data.

Thirty out of 50 states reported more new infections in the week ended March 21 compared with the previous seven days, up from 19 states in the prior week, according to the Reuters analysis.

Nationally, the weekly number of new cases had been on a downward trend since January, though health authorities have warned that infections could surge again if Americans relaxed social distancing restrictions too quickly. More infectious variants have also spread across the country.

“I am worried that if we don’t take the right actions now we will have another avoidable surge just as we are seeing in Europe right now and just as we are so aggressively scaling up vaccinations,” said Dr. Rochelle Walensky, director of the Centers for Disease Control and Prevention, on Monday.

The Northeast logged some of the highest rates of infection per capita, led by New Jersey, New York and Rhode Island.

Deaths from COVID fell 15% to 7,793 last week, or about 1,100 per day, according to the Reuters analysis. Health officials hope the country’s vaccination effort can prevent a rise in deaths even if cases surge again.

For a fourth week, daily average vaccinations set a record, with 2.5 million shots given per day last week. As of Sunday, 25% of the U.S. population has received at least one dose of a vaccine, up from 21% a week ago, according to the Centers for Disease Control and Prevention. About 13% has received two doses, up from 11%.

The average number of COVID-19 patients in U.S. hospitals fell 6% to 36,000, the lowest since October, according to a Reuters tally.

Hospitalizations have fallen for 10 weeks nationally, but they are rising in 18 states, up from four states the previous week.

(Graphic by Chris Canipe, writing by Lisa Shumaker, editing by Tiffany Wu)