A state of emergency was declared by Missouri Governor Jay Nixon Wednesday night as a severe storm roared through northern and central Missouri. St. Louis had at least three confirmed tornadoes rip through the nation’s 19th largest metro area.

Many residents are without power and many homes have been significantly damaged.

“This was a strong system of storms that caused damage to communities in several areas of our state,” Gov. Nixon said in a statement obtained by Fox News. “We will continue to work closely with local officials to assess damages and provide any needed assistance.”

Four people were injured in north-central Arkansas when a tornado ripped through areas near Botkinburg.

The northern section of the storm dumped snow and ice across the upper midwest. The level of dangerous winds combined with the storm led Minnesota Governor Mark Dayton to send out the state’s National Guard to help residents.

Some parts of Minnesota received up to 14 inches of snow.

North and South Dakota are also being pounded by the storm that dumped almost two feet of snow across the states. Tens of thousands of residents are without power as a second wave of the storm is threatening to double that number.

Wisconsin is reporting flooding due to the amount of rain, ice and snow that has fallen in the state from the storm. A second wave is expected to hit Thursday increasing fears of flooding.